Pairwise Alignments

Query, 640 a.a., Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) from Variovorax sp. SCN45

Subject, 563 a.a., AMP-dependent synthetase from Vibrio cholerae E7946 ATCC 55056

 Score =  181 bits (458), Expect = 1e-49
 Identities = 158/600 (26%), Positives = 262/600 (43%), Gaps = 85/600 (14%)

Query: 1   MLAHAEARPESPAVREKDLGIWQTWTWNAVAQEVREMACGLASLGFKAFDNLAIVGANRP 60
           +L  A+ RP    +++     +  +T+  VA +   +   L +LG    D +A++  N  
Sbjct: 23  LLRWAKERPNEVYLKQIINRQFVEFTYAEVADKALRLVSALRALGADPGDKVALISKNCA 82

Query: 61  HLYMAVIAAQSLRGVPVPLYQDAVAGEMVFMLQDAGIEFVIVEDQEQVDKLLECRDIQQG 120
             ++  +A      + VP++  A +  + + L+ +  + +IV                 G
Sbjct: 83  EWFICDLAMMLGDYISVPIFPTAGSETIDYCLEHSESKILIV-----------------G 125

Query: 121 KLP---AIRHVIYDDPKGLR---HYDQPGLMSYE-QLRALGREFDKANPGYYDRAVASGE 173
           KL    A  HV+ + P  +     Y       YE Q      +  +  P ++D  + S  
Sbjct: 126 KLDDNKATAHVLAERPNLISISLPYPSAAKCQYEFQTLIKQHQPSEERPTHFDEKLMS-- 183

Query: 174 ATDVGVILYTSGTTGRPKGVCQTHASFIAAGRGGVETDRLGPGDNIMSYLPMAWVGDHLF 233
                 I+YTSGT+G+PKG   T+ +F  + +  +    +   D + SYLP+A + + ++
Sbjct: 184 ------IVYTSGTSGQPKGAMLTYGAFTWSAQQLINHIGIEENDRLFSYLPLAHITERVY 237

Query: 234 SVAQWLVGGFTLNCPESSETVMNDMREIGPSYYFGPPRTFEGLLTAVSIRMEDAAAPKRW 293
                ++GG     PES +T + D++   P+ +   PR    L T    R++D    K+ 
Sbjct: 238 IFGSSIIGGVLTAFPESLDTFIEDVKMHRPTLFISVPR----LWTLFQQRIQDKLPQKK- 292

Query: 294 LYAKFMALARRVGADILNGAPVGMGDRALYALGNLLIYGPLRNVLGMSRIRVAYTAGAAI 353
                         +IL   P            N LI   L + LG+ + RV     A +
Sbjct: 293 -------------LNILLKIP----------FVNSLIKRKLADGLGLDQARVLGCGSAPV 329

Query: 354 GPDLFRFYRSIGVNLKQFYGQTETCAYVCLQQDGKV-KLQTVGTAAPGIELKIAADGEVL 412
            P L  +YRS+G+N+ + +G TE+ AY  L    +  K+ TVG A PGIELKIA D E+L
Sbjct: 330 SPALLEWYRSVGLNITEAWGMTESFAYSTLNYPFRADKIGTVGNAGPGIELKIAEDEEIL 389

Query: 413 VRGVSVLKEYYKRPDATAEVLDANGYFHTGDAGVLDSEGHLRIIDRAKDVGRLVGGAIFA 472
           VR   +   YYK   ATAE  + +G+ HTGD G LDSEG+L I  R KD  +   G   A
Sbjct: 390 VRSKGLFAGYYKNDTATAESFNDDGWLHTGDIGSLDSEGYLTIQGRKKDTFKTAKGKFVA 449

Query: 473 PNYIENKLKFFPQIKEAVCFGNARD-EVCAAINIDFEAVGNWAERRGLAYGGYVDLAGKP 531
           P  IE KL  + +++     G+     +  A+  +F         R              
Sbjct: 450 PVPIEKKLFEYSRVEMMCLIGSGLPAPILLAVPHNFPHFDRARYER-------------- 495

Query: 532 DVLALVAECIGKVNADLATEDGMGETQIARFLVLHKELDPDDDELTRTRKVRRGFIAEKY 591
                  + I ++N++L + +     QI   L++      D+  LT T K++R  + +KY
Sbjct: 496 ----TTQKVIARINSELESHE-----QIKGVLMIKDPWSIDNGILTPTLKIKRHVLEKKY 546