Pairwise Alignments

Query, 361 a.a., D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) from Variovorax sp. SCN45

Subject, 363 a.a., 3-isopropylmalate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

 Score =  185 bits (470), Expect = 1e-51
 Identities = 134/364 (36%), Positives = 195/364 (53%), Gaps = 21/364 (5%)

Query: 5   RIAVIAGDGIGKETMPEGLRVLEAAATRFGIDLKFDHFDFSSWDYYEKHGQMLPDNWKDQ 64
           +IAV+ GDGIG E M +  +VL+A   + GI    +  D       + HG  LP++    
Sbjct: 7   KIAVLPGDGIGPEVMAQAHKVLDAIEQKHGIRFSREEHDVGGIAI-DNHGCPLPESTLRA 65

Query: 65  IGGHDAIFFGAVG---WPEKIPDHVSLWGSLLMFRREFDQYINLRPARLMPGIIA-PVVR 120
               DA+ FG+VG   W    P+     G+LL  R+ F  + NLRPA++  G+ A   +R
Sbjct: 66  CEEADAVLFGSVGGPKWEHLPPNEQPERGALLPLRKHFQLFCNLRPAQIHQGLEAFSPLR 125

Query: 121 RDGTPREPGEIDMYIVRENTEGEY-SSIGGRMYQGTPREIVVQETVMSRVGVDRVLKFAF 179
            D + R     D+ +VRE T G Y     GR  +G   E      V  R  ++R+ + AF
Sbjct: 126 ADISARG---FDIVVVRELTGGIYFGQPKGREGEGA-HEKAFDTEVYHRFEIERIARIAF 181

Query: 180 ELAQSRPKKHLTSATKSNGISITMPYWDERVAEMGKSYPGITLDKFHIDILTAHFVQRPD 239
           E A+ R KK + S  K+N +  ++  W E V+E+ K YP ++L   +ID  T   ++ P 
Sbjct: 182 ESARLRRKK-VCSIDKANVLQSSI-LWREVVSEIAKEYPDVSLSHMYIDNATMQLIKDPA 239

Query: 240 FFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTTPSLFEPVHGSAPDIAGKGIA 299
            FDV++ SN+FGDILSD     TG++G+ PSA++N  +    L+EP  GSAPDIAGK IA
Sbjct: 240 QFDVMLCSNIFGDILSDECAMITGSMGMLPSASMNESKF--GLYEPAGGSAPDIAGKNIA 297

Query: 300 NPIGQIWCGAMMLEF-LGHKQAHDAILSTIEKVLAPQSGAPRTPDIGGK---ASTSDLGK 355
           NP+ QI   A+ML + LG + A   I + + + LA       T D+ G     STS +G 
Sbjct: 298 NPVAQILSAALMLRYSLGEEAAARDIENAVSQALA---AGELTADLAGSKPALSTSAMGD 354

Query: 356 AIAA 359
            IA+
Sbjct: 355 KIAS 358