Pairwise Alignments

Query, 407 a.a., Phosphopantothenoylcysteine decarboxylase (EC 4.1.1.36) / Phosphopantothenoylcysteine synthetase (EC 6.3.2.5) from Variovorax sp. SCN45

Subject, 396 a.a., bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC from Methanococcus maripaludis S2

 Score =  117 bits (293), Expect = 6e-31
 Identities = 94/380 (24%), Positives = 191/380 (50%), Gaps = 27/380 (7%)

Query: 4   LAGKHIVLGLTGGIACYKSAELCRLFVKAGATVQVVMTEAAEQFITPVTMQALSGRTVYT 63
           L GK +V+ +T  IA  ++  L R  ++ GA V  +MTE  +  +   +++   G  V  
Sbjct: 15  LDGKKLVVAVTSSIAAIEAPRLMRELIRHGAEVYCIMTEETKDIVGKYSLEFGCGNEVMD 74

Query: 64  SQWDTREPNNMPHINLSREADAIVLAPCSADFIARLVQGRSDDLLSLMCLARPMDRIPLL 123
                +    + H++L  + D +++ P +A+ I+++    +D++++   +   +++ P++
Sbjct: 75  -----KITGKIEHVDLYNKCDGMIVFPATANIISKISLNIADNIVNTTAMMF-LEKKPII 128

Query: 124 IAPAMNREMWGHPATQRNLMQVAADGATVLGVGNGWQACGETGDGRML-EPAQLLEDITA 182
           IAP+M++ M     T R+ ++  ++   V  +G+  +   E      + E ++L  D+  
Sbjct: 129 IAPSMHQNMLD---TVRDHIKNLSEKNNVFVMGSKMEE--EKAKAISIDEVSKLAIDV-- 181

Query: 183 FFSPKLLAGQKVLVTAGPTFESLDPIRGITNHSSGKMGFAIARAAREAGAEVTLVAGPVH 242
            FS +    +KVL+ +G T E +D +R ITN SSGK G ++A        +V ++ G + 
Sbjct: 182 -FSDRKEERKKVLILSGGTAEPIDKVRVITNLSSGKTGVSLAEEFCRQNYDVDVIKG-LG 239

Query: 243 LPTPRGVTRVDVLSAQDMLEATTRAAEFASIFVATAAVADWRPATQSDQKIKKDGSGKTP 302
              P  +   +V+++Q+ML+      E A I ++ AA++D+ P T  + K+  D   KT 
Sbjct: 240 KDVPYYINSENVITSQEMLKKALELGESADIIISCAAISDYAPETNFEGKLSSD--IKTQ 297

Query: 303 VLEFVENADILLTVARSERAQSKKLFCVGFAAE----SENLAAHAKAKRERKGIPLLVGN 358
           V++  +   +L       R +  K   VG+ AE     + L   A ++ E+  + +++ N
Sbjct: 298 VIKLKQTPKVL----EELRKKFPKKIIVGYKAEYGINLDELKEKAISRLEKYNLDVIIAN 353

Query: 359 -IGPLTFGQDDNALLLVDAD 377
            +    FG D N +L++D +
Sbjct: 354 DLSKHYFGDDLNEVLIIDKE 373