Pairwise Alignments

Query, 489 a.a., Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain from Variovorax sp. SCN45

Subject, 500 a.a., IMP dehydrogenase from Methanococcus maripaludis S2

 Score =  454 bits (1167), Expect = e-132
 Identities = 251/488 (51%), Positives = 337/488 (69%), Gaps = 15/488 (3%)

Query: 6   KALTFDDVLLVPAFSQVLPKDTSLATKLSRNITLNLPLISAAMDTVTEARLAIAIAQEGG 65
           +A TFDDVLLVP  S V PK T ++  ++  + LN+P+ISAAMDTV+E  LAIA+A+ GG
Sbjct: 15  RAYTFDDVLLVPNKSFVDPKTTDVSVDIA-GLKLNIPIISAAMDTVSEKDLAIALARRGG 73

Query: 66  MGIVHKNLTAQQQAAEVARVKRYESGVLRDPVVITPTHSVRQVMALSDQLGISGFPVVDA 125
           + ++H+N+T ++Q   V  VK  E+ V+RD V + P+ SV     +  +  +SG PVV  
Sbjct: 74  IAVIHRNMTVEEQLKHVKAVKMAENLVIRDVVTVEPSSSVLDAERIMYEYNVSGLPVVSE 133

Query: 126 GK-VVGIVTGRDLRFENRYDVPVSEIMTRREKLITVPDGTTLAEAKALLNKYKLERLLVI 184
            K +VGI+T RDL+F    +V V  +MT+  +++ V + T   E    L + K+ERL ++
Sbjct: 134 NKTLVGILTTRDLKFVPDKNVAVETVMTK--EVLHVHEDTPYEEILNRLYENKIERLPIL 191

Query: 185 NGDW-ELKGLITVKDITKQTSFPNAARDANGRLRVGAAVGVGDGTEERVEALVKAGVDAI 243
           + +  EL G++T++DI K+  +P+AARD++G+L V AA G  D   ER EALV AGVDA+
Sbjct: 192 DKNTKELLGMVTLRDILKRKKYPDAARDSDGKLVVAAACGPSDF--ERAEALVLAGVDAV 249

Query: 244 VVDTAHGHSAGVIERVRWVKK--NYPQVDVIGGNIATGDAARALADVGADAVKVGIGPGS 301
            +D AH H+  V+E V+ +K+     +  +  GNIATG+AA  L   GADA+KVGIGPGS
Sbjct: 250 AIDCAHAHNMQVVENVKKLKEILKGTKTKLFVGNIATGEAAEDLIKAGADALKVGIGPGS 309

Query: 302 ICTTRIVAGVGVPQIMAVDSVATALQGTGIPLISDGGVRYSGDIAKAIAAGASTVMMGSM 361
           ICTTR+VAGVGVPQ+ AV  VA   +  G+P+I+DGG++YSGDIAKAIAAGA+ VM+GS+
Sbjct: 310 ICTTRVVAGVGVPQLTAVAEVAEVAKKYGVPVIADGGIKYSGDIAKAIAAGANAVMVGSL 369

Query: 362 FAGTEEAPGEIVLYQGRSYKSYRGMGSIGAMQQGS---ADRYFQESTTGNPNTDKLVPEG 418
            AGTEEAPG ++   GR YK YRGMGS+GAM   S   ADRYFQ   +G+    KLVPEG
Sbjct: 370 LAGTEEAPGSLMTINGRKYKQYRGMGSLGAMCGSSGNVADRYFQ---SGHMKHSKLVPEG 426

Query: 419 IEGRVPYKGSIVSIVYQMAGGVRASMGYCGCATIADMQNKAEFVEITTAGIRESHVHDVQ 478
           IEG VPYKG    IVYQ+ GG+R+SMGYCG   +++M  KA FV IT +G +ESH HDV 
Sbjct: 427 IEGAVPYKGPTSDIVYQLIGGLRSSMGYCGAQNLSEMHEKARFVIITQSGQKESHPHDVL 486

Query: 479 ITKEAPNY 486
           IT EAPNY
Sbjct: 487 ITNEAPNY 494