Pairwise Alignments
Query, 1947 a.a., Excinuclease ABC subunit A, dimeric form from Variovorax sp. SCN45
Subject, 940 a.a., UvrABC system protein A from Vibrio cholerae E7946 ATCC 55056
Score = 543 bits (1398), Expect = e-158
Identities = 375/1033 (36%), Positives = 529/1033 (51%), Gaps = 131/1033 (12%)
Query: 6 IRIRGARQHNLQNLDLDIRTGEMTVVTGPSGSGKSSLVFDTLYAEGQRRYVETFSAYARQ 65
I +RGAR HNL+N++L I ++ V+TG SGSGKSSL FDTLYAEGQRRYVE+ SAYARQ
Sbjct: 4 IEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQ 63
Query: 66 FLDRMDKPAVDKVEGVPPAIAIDQTNPVRSSRSTVGTMTELNDHLKLLFARAADLFDRET 125
FL M+KP VD +EG+ PAI+I+Q + + RSTVGT+TE+ D+L+LL+AR + E
Sbjct: 64 FLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEH 123
Query: 126 ALPVRHDSPDSIYAQIAERAAAAGDPRLVVTFPVELPASTTAEEVTQWLSASGFTRVQSE 185
+P++ + + ++ E + ++++ + + + L+A GF R + +
Sbjct: 124 QVPLKAQTISQMVDKVLELPEGS---KMMLLATIVKERKGEHVKTLENLAAQGFIRARID 180
Query: 186 REVATPTGPRKV-------LDVVADRFRASSAERSRVVEAIEVALKRGSGRVTVHATGAE 238
E T P K+ ++V+ DRF+ S + R+ E+ E AL+ G V V A
Sbjct: 181 GETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVV----AP 236
Query: 239 ENAPTDVWKFSTGLHCPESDIRYADPIPSMFSFNSAVGACDTCRGFGRVIGVDLGLVIPN 298
+ FS CP + P +FSFN+ GAC TC G G D VI +
Sbjct: 237 MEGDGEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQD 296
Query: 299 DKLTLRAGAIKTIQTPAWKEAQ----DDLMRHAETAGIPRDTPWNKLTDEQKHWVIEGTP 354
L+L GAI+ W + L AE TP+NKL+ + + ++ G+
Sbjct: 297 ANLSLAQGAIR-----GWDQKNFYYFQMLTALAEHYDFDVHTPFNKLSKKIQEIILHGSG 351
Query: 355 ---------------NYKEGNWNKQWYGVRRFFAYLESKAYKMHIRVLLSKYRSYTQCPT 399
K+ + + + R + ES + +R L+KY S C +
Sbjct: 352 RTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNS----VREELAKYISNKPCSS 407
Query: 400 CSGARLKLDSLIWRIGSKEDADAVLPP--EKRFMPTGAKWTRAQLEALPGLCLHDLMLLP 457
C G RLK+++ I D LP E + +LE +M
Sbjct: 408 CDGTRLKIEARNVFIN-----DTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEI 462
Query: 458 IERLRKFFDRMGQGMAPSLAGGGQAALASPAASNEAESPHPNLPPAGEGARQGEAQALKL 517
+RL +F +G + NL + E GEAQ ++L
Sbjct: 463 NDRL-QFLVNVGLN-------------------------YLNLSRSAETLSGGEAQRIRL 496
Query: 518 LFEEITTRLRYLHDVGIGYLTLDRQSRTLSGGEVQRINLTTALGTSLVNTLFVLDEPSIG 577
+I L VG+ Y+ LD S L + +R+ T +L NT+ V
Sbjct: 497 A-SQIGAGL-----VGVMYV-LDEPSIGLHQRDNERLLQTLTHLRNLGNTVLV------- 542
Query: 578 LHPRDMNRITEAMLRLRDAGNTLVVVEHDPAVMLAADRVIDMGPGPGARGGQIVFDGTTD 637
VEHD + AD VID+GPG G GG +V +G +
Sbjct: 543 -------------------------VEHDEDAIRMADHVIDIGPGAGVHGGMVVAEGNVE 577
Query: 638 Q-LRDADTLTGQYLGGRKKIGMGFKRLVSENTHRLILEGVREHNLKNITVDFPLARLVCV 696
+ + + ++LTGQYL G KKI + +R + + L+G +NLKN+ + P+ CV
Sbjct: 578 EIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCV 637
Query: 697 TGVSGSGKSTLIQDVLAP-ALMRHFGKATETPGAHDRMLGADHLGDVVFVDQSPIGKTAR 755
TGVSGSGKSTLI D A G T TP + + G +H V+ +DQSPIG+T R
Sbjct: 638 TGVSGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPR 697
Query: 756 SNPASYVGAWDAIREIFATAALSRQRGYTASKFSFNSGDGRCPTCGGSGFEHVEMQFLSD 815
SNPA+Y G + IRE+FA SR RGY +FSFN GRC C G G VEM FL D
Sbjct: 698 SNPATYTGIFTPIRELFAGTQESRSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPD 757
Query: 816 VYLRCPDCDGKRYRPEILEVRVERKGKSYNVADVLDLTVAEAAAVFEADRDVLRVLQPIS 875
VY+ C C GKRY E LEVR KGK+ + +VLD+TV +A F+ + R LQ +
Sbjct: 758 VYVPCDVCKGKRYNRETLEVRY--KGKT--IDEVLDMTVEDAREFFDPVPVIARKLQTLM 813
Query: 876 DVGLDYVKLGQPVPTLSGGEAQRLKLAGFLAEAAKGATASKQSVARKGTLFLFDEPTTGL 935
DVGL Y++LGQ TLSGGEAQR+KLA L++ G TL++ DEPTTGL
Sbjct: 814 DVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGK-----------TLYILDEPTTGL 862
Query: 936 HFDDIARLMRALRKLLEAGHSLIVIEHNLDVIRASDWLIDLGPEGGEGGGQVVAEGTPEQ 995
HF DI +L+ L +L + G++++VIEHNLDVI+ +DW+IDLGPEGG+GGG ++AEGTPE
Sbjct: 863 HFHDIQQLLSVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPED 922
Query: 996 LRENRASLTGAAL 1008
+ + AS T L
Sbjct: 923 VAQIEASHTARFL 935
Score = 503 bits (1296), Expect = e-146
Identities = 277/576 (48%), Positives = 365/576 (63%), Gaps = 37/576 (6%)
Query: 1371 LADVACPTCEGTRLNATARAVSFGASLANGSGGIGITELARMSVTEVRQWFEGLALTGRE 1430
+++ C +C+GTRL AR V + + + +S+ + +F+ L L G+
Sbjct: 400 ISNKPCSSCDGTRLKIEARNVFINDT--------ALPTIVELSIADALTFFQELKLEGQR 451
Query: 1431 AEIARDLVPEIKSRLEFLEEVGLGYLTLDRGAPTLSGGEAQRIRLAAQLGSNLQGVCYVL 1490
A+IA ++ EI RL+FL VGL YL L R A TLSGGEAQRIRLA+Q+G+ L GV YVL
Sbjct: 452 AQIAEKVMKEINDRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVL 511
Query: 1491 DEPTIGLHARDNQILLNALHKLGEKGNTLVVVEHDEDTIRRADHIIDIGPSAGKRGGRLV 1550
DEP+IGLH RDN+ LL L L GNT++VVEHDED IR ADH+IDIGP AG GG +V
Sbjct: 512 DEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIGPGAGVHGGMVV 571
Query: 1551 AEGTVADIQNAGDSQTGRYLRDAIRHPLQARRSIPSPDPQAEDNGEWLTVHGADLHNLQD 1610
AEG V +I +S TG+YL + + +R+ +D + + + GA +NL++
Sbjct: 572 AEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRT-------PKDAKKTVELKGAVGNNLKN 624
Query: 1611 LTATLPLHRLVVVTGVSGSGKSTLARDVLLASVQGIVVQRMTKAGRDADAAGKRPAWAGC 1670
+ ++P+ VTGVSGSGKSTL D K A A
Sbjct: 625 VDLSIPVGLFTCVTGVSGSGKSTLINDTFF------------KIAHTALNGATTATPAPY 672
Query: 1671 RKVDGYETIDRVLEVDQTPIGKTPRSCPATYIGFWDTIRKLFADTLEAKARGYGPARFSF 1730
R + G E D+V+++DQ+PIG+TPRS PATY G + IR+LFA T E+++RGY P RFSF
Sbjct: 673 RSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQESRSRGYQPGRFSF 732
Query: 1731 NTGEGRCPGCEGAGVRTIEMSFLPDVKVPCEVCHGARFNPETLAVSWRGKSIGDVLKMEV 1790
N GRC C+G GV +EM FLPDV VPC+VC G R+N ETL V ++GK+I +VL M V
Sbjct: 733 NVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTV 792
Query: 1791 DEAVEFFASMPNIAHPLQLLKDVGLGYLTLGQPSPTLSGGEAQRIKLVTELSKVRDDITR 1850
++A EFF +P IA LQ L DVGL Y+ LGQ + TLSGGEAQR+KL ELSK
Sbjct: 793 EDAREFFDPVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSK------- 845
Query: 1851 RGQKAPHTLYVLDEPTVGLHMADVEKLIHVLHRLVNGGHSVVVIEHDLDLIAEADWIIDL 1910
+ TLY+LDEPT GLH D+++L+ VLHRL + G++VVVIEH+LD+I ADWIIDL
Sbjct: 846 --RDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDHGNTVVVIEHNLDVIKTADWIIDL 903
Query: 1911 GPEGGNAGGRIVAAAPPEEVVRL-GTHTGVALAPVL 1945
GPEGG GG I+A PE+V ++ +HT L P+L
Sbjct: 904 GPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLL 939
Score = 218 bits (555), Expect = 3e-60
Identities = 120/310 (38%), Positives = 177/310 (57%), Gaps = 14/310 (4%)
Query: 1041 DAVQIVNAREHNLKNLSVDIPRGKFSVVTGVSGSGKSTLAFDILFNEGQRRYLESLNAYA 1100
D +++ AR HNLKN+++ IPR K V+TG+SGSGKS+LAFD L+ EGQRRY+ESL+AYA
Sbjct: 2 DKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYA 61
Query: 1101 RSIVQPAGRPEVDAVYGIPPTVAIEQRLSRGGRKSTVGTTTEVWHFLRLLYVKLGIQHCI 1160
R + +P+VD + G+ P ++IEQ+ + +STVGT TEV+ +LRLLY ++G C
Sbjct: 62 RQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCP 121
Query: 1161 HDGAAVQPQTPDSIAAQLMRNFKGQHIGLLAPLVSNRKGVYTELADWARPRGFTHLRVDG 1220
++ QT + +++ +G + LLA +V RKG + + + +GF R+DG
Sbjct: 122 EHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKGEHVKTLENLAAQGFIRARIDG 181
Query: 1221 DFLPTTGFPRIDRFKEHSIELPVASLDVLPSKETELREALTKALEHGKGVVHVLSELDGL 1280
+ T P+++ K+H+IE+ V V + L E+ ALE G+V V
Sbjct: 182 ETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVV------- 234
Query: 1281 RAAMMAGVSAAGIGRVHVFSTLRACPVCSTSYAELDPRLFSYNSKHGWCPDCVGTGVKLS 1340
G G +FS ACP C S EL+PRLFS+N+ G CP C G GV+
Sbjct: 235 -------APMEGDGEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQY 287
Query: 1341 KDQRKVFDDS 1350
D +V D+
Sbjct: 288 FDPDRVIQDA 297
Score = 146 bits (369), Expect = 1e-38
Identities = 101/280 (36%), Positives = 149/280 (53%), Gaps = 44/280 (15%)
Query: 820 CPDCDGKRYRPEILEVRVERKGKSYNVADVLDLTVAEAAAVF-----EADRDVL--RVLQ 872
C CDG R + E V + + +++L++A+A F E R + +V++
Sbjct: 405 CSSCDGTRLKIEARNVFINDTA----LPTIVELSIADALTFFQELKLEGQRAQIAEKVMK 460
Query: 873 PISD-------VGLDYVKLGQPVPTLSGGEAQRLKLAGFLAEAAKGATASKQSVARKGTL 925
I+D VGL+Y+ L + TLSGGEAQR++LA S+ G +
Sbjct: 461 EINDRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLA------------SQIGAGLVGVM 508
Query: 926 FLFDEPTTGLHFDDIARLMRALRKLLEAGHSLIVIEHNLDVIRASDWLIDLGPEGGEGGG 985
++ DEP+ GLH D RL++ L L G++++V+EH+ D IR +D +ID+GP G GG
Sbjct: 509 YVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIGPGAGVHGG 568
Query: 986 QVVAEGTPEQLRENRASLTGAALADYELAIGPDAYKVAERAARRYIANAKKAPGSDAVQI 1045
VVAEG E++ N SLTG L+ + P+ +R +AKK V++
Sbjct: 569 MVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPE---------QRTPKDAKK-----TVEL 614
Query: 1046 VNAREHNLKNLSVDIPRGKFSVVTGVSGSGKSTLAFDILF 1085
A +NLKN+ + IP G F+ VTGVSGSGKSTL D F
Sbjct: 615 KGAVGNNLKNVDLSIPVGLFTCVTGVSGSGKSTLINDTFF 654
Score = 67.8 bits (164), Expect = 7e-15
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 23/141 (16%)
Query: 1598 LTVHGADLHNLQDLTATLPLHRLVVVTGVSGSGKSTLARDVLLASVQGIVVQRMTKAGRD 1657
+ V GA HNL+++ T+P +L+V+TG+SGSGKS+LA D L A Q V+ ++ R
Sbjct: 4 IEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQ 63
Query: 1658 ADAAGKRPAWAGCRKVDGYETIDRVLEVDQTPIGKTPRSCPATYIGFWDTIRKLFADTLE 1717
+ ++P VD E + + ++Q PRS T +D +R L+A
Sbjct: 64 FLSLMEKP------DVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYA---- 113
Query: 1718 AKARGYGPARFSFNTGEGRCP 1738
GE RCP
Sbjct: 114 -------------RVGEPRCP 121
Score = 53.5 bits (127), Expect = 1e-10
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 5 SIRIRGARQHNLQNLDLDIRTGEMTVVTGPSGSGKSSLVFDTLYAEGQRRYVETFSAYAR 64
++ ++GA +NL+N+DL I G T VTG SGSGKS+L+ DT + +A
Sbjct: 611 TVELKGAVGNNLKNVDLSIPVGLFTCVTGVSGSGKSTLINDTFFKIAHTALNGATTATPA 670
Query: 65 QFLDRMDKPAVDKVEGVPPAIAIDQTNPVRSSRSTVGTMTELNDHLKLLFA 115
+ DKV I IDQ+ R+ RS T T + ++ LFA
Sbjct: 671 PYRSIQGLEHFDKV------IDIDQSPIGRTPRSNPATYTGIFTPIRELFA 715
Score = 52.4 bits (124), Expect = 3e-10
Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 13/114 (11%)
Query: 670 RLILEGVREHNLKNITVDFPLARLVCVTGVSGSGKSTLIQDVLAPALMRHFGKATETPGA 729
++ + G R HNLKNI + P +L+ +TG+SGSGKS+L D L R + E+ A
Sbjct: 3 KIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRY---VESLSA 59
Query: 730 HDRML-------GADH---LGDVVFVDQSPIGKTARSNPASYVGAWDAIREIFA 773
+ R DH L + ++Q RS + +D +R ++A
Sbjct: 60 YARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYA 113
Score = 31.2 bits (69), Expect = 7e-04
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 1725 PARFSFNTGEGRCPGCEGAGVR 1746
P FSFN G CP C+G GV+
Sbjct: 264 PRLFSFNNPAGACPTCDGLGVQ 285