Pairwise Alignments

Query, 512 a.a., 2-isopropylmalate synthase (EC 2.3.3.13) from Variovorax sp. SCN45

Subject, 386 a.a., homocitrate synthase family protein from Methanococcus maripaludis S2

 Score =  237 bits (604), Expect = 6e-67
 Identities = 148/370 (40%), Positives = 211/370 (57%), Gaps = 15/370 (4%)

Query: 7   IFDTTLRDGEQSPGASMTRDEKMRIAKLLERLKVDVIEAGFPASSNGDFEAVKAIANAIK 66
           ++DTTLRDGEQ+PG     D+K+ IAK L+ LK+  IEAGFP  S  + +A+K+I     
Sbjct: 20  LYDTTLRDGEQTPGVCFAGDQKLEIAKKLDELKIKQIEAGFPIVSENERKAIKSITGEGL 79

Query: 67  DSTVCGLSRANDRDIARAAEA-LKGAARGRIHTFIATSPLHMEKKLRMTPDEVHEQARLA 125
           ++ +  LSR    DI +A E  + G     I TFIATSP+H++ KL    DEV E    A
Sbjct: 80  NAQILALSRVLKEDIDKAIECDVDG-----IITFIATSPMHLKYKLHKNLDEVEEMGMKA 134

Query: 126 VRFARNQIGDVEFSPEDGYRSDPDFLCRVLETVIAEGATTINVPDTVGYAIPELYGNFIK 185
           V +A++    V FS ED  R+  + + R+ +     GA  +++ DT+G A P+   +   
Sbjct: 135 VEYAKDHGLFVAFSAEDATRTPLEDIIRIHKNAEEHGADRVHIADTLGCATPQAMYHICS 194

Query: 186 MLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNCSLEEV 245
            L + +    KA   VHCHND G AV NS+ G+ IGGA+ V  T+NG+GERAGN ++EE+
Sbjct: 195 ELSKHL---KKAHIGVHCHNDFGFAVINSIYGL-IGGAKAVSTTVNGIGERAGNAAIEEI 250

Query: 246 VMAVKTRKDYFGLDLRIDTQHIVAASRMVSQTTGFVVQPNKAVVGANAFAHASGIHQDGV 305
            MA+K   D+   D+ ++T+ +   S++V   +   +  NK +VG   F H SGIH D V
Sbjct: 251 AMALKVLYDH---DMGLNTEILTEISKLVENYSKIKIPENKPLVGEMVFYHESGIHVDAV 307

Query: 306 LKARDTYEIMRAEDVGWAANKIVLGKLSGRNAFKQRLQELGVAMDSEGEINAAFLRFKEL 365
           L+   TYE    E +G    KI+LGK SG  A   RLQELG+   S  E+     + KE 
Sbjct: 308 LENPLTYEPFLPEKIG-QKRKIILGKHSGCRAVAHRLQELGLEA-SRDELWEIVKKTKET 365

Query: 366 ADRKSEIFDE 375
            +  +EI DE
Sbjct: 366 REDGTEISDE 375