Pairwise Alignments

Query, 1039 a.a., bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA from Vibrio cholerae E7946 ATCC 55056

Subject, 482 a.a., succinate-semialdehyde dehydrogenase I, NADP-dependent from Escherichia coli BL21

 Score =  189 bits (479), Expect = 5e-52
 Identities = 141/452 (31%), Positives = 220/452 (48%), Gaps = 18/452 (3%)

Query: 593  QIGQVFHANLDHVSAAIDSAQQAFATWNALDAKERASKLDALADLLELHMPELVALCHQE 652
            ++G V     D   AAID+A +A   W AL AKERA+ L    +LL  H  +L  L   E
Sbjct: 38   KLGSVPKMGADETRAAIDAANRALPAWRALTAKERANILRNWFNLLMEHQDDLARLMTLE 97

Query: 653  AGKTIHDSIDEVREAVDFCRYYGKQVDVLGEFSVESFDGSTRR-VSRQGRGVFVCISPWN 711
             GK + ++  E+  A  F  ++ ++   +   ++       R  V +Q  GV   I+PWN
Sbjct: 98   QGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWN 157

Query: 712  FPLAIFLGQISAALVAGNTVIAKPAEQTSLIAYRAVELMQEAGFPAGTIQLLPGRGADIG 771
            FP A+   +   AL AG T++ KPA QT   A    EL   AG PAG   ++ G    +G
Sbjct: 158  FPAAMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVG 217

Query: 772  SALTSHPAIAGVAFTGSTATAQRINQTLAQREAAPVPFIA-ETGGQNAMIVDSTALPEQV 830
            + LTS+P +  ++FTGST     I + L ++ A  +  ++ E GG    IV   A  ++ 
Sbjct: 218  NELTSNPLVRKLSFTGST----EIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKA 273

Query: 831  VRDVLRSAFASAGQRCSALRVLFVQQDIADRVITLIQGAMQELKVSVPHLHQTDVGPVID 890
            V   L S F +AGQ C     L+VQ  + DR    +Q A+ +L +         +GP+ID
Sbjct: 274  VEGALSSKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLEKGVTIGPLID 333

Query: 891  EKAKQKLLAHIEHMSQTQKKIAQLTLDDACQH--GDFVAPTAF-EIDDIAALS-EEQFGP 946
            EKA  K+    EH++   +K A++          G+F  PT   ++   A +S EE FGP
Sbjct: 334  EKAVAKV---EEHIADALEKGARVVCGGKADERGGNFFQPTILVDVPANAKVSKEETFGP 390

Query: 947  ILHIVRFKARELAQIVDKINQTGFGLTMGIHSRNETTYRWIEKHARVGNCYINRDQVGAV 1006
            +  + RFK  + A ++ + N T FGL    ++R+ +    + +    G   IN   +   
Sbjct: 391  LAPLFRFK--DEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNE 448

Query: 1007 VGVQPFGGQGLSGTGPKAGGPHYLYRFTQVQY 1038
            V   PFGG   SG G + G  + +  + +++Y
Sbjct: 449  VA--PFGGIKASGLG-REGSKYGIEDYLEIKY 477