Pairwise Alignments

Query, 527 a.a., signal transduction histidine-protein kinase/phosphatase UhpB from Vibrio cholerae E7946 ATCC 55056

Subject, 500 a.a., sensor histidine protein kinase phosphorylates UhpA (VIMSS) from Escherichia coli BW25113

 Score =  283 bits (725), Expect = 8e-81
 Identities = 184/516 (35%), Positives = 289/516 (56%), Gaps = 26/516 (5%)

Query: 2   AKLFPLIFAFVLYSISQFSLWNVSQYLSHNPLQAYLLFPTGLRLAVYLLARPTYVWVWLL 61
           ++L  +I  F ++S + F LW++S +L   P  A LLFP GLRL + L     Y  V L 
Sbjct: 6   SRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLG 65

Query: 62  SDMLLAGVILVLLPDQSSPLMLLMPWVVWL-AAVIARQHWPKLHLYWQKLLLIVALVLLH 120
           ++ LL   +   +     PL+++   +  L  A+I+R    +    W+ LLL  A +   
Sbjct: 66  AEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISRYRHQR---DWRTLLLQGAALTAA 122

Query: 121 TILVGITFTLLAKPLHMGAETLIAVSIASLTGGIVLTPFLYLVADYLSHQTWHPLSPQLI 180
            +L  + +      L  G E+  A+ + +LTGG+ L P   +   YL++ TW PL P L+
Sbjct: 123 ALLQSLPW------LWHGKESWNAL-LLTLTGGLTLAPICLVFWHYLANNTWLPLGPSLV 175

Query: 181 HHDVKLKPKMLMWSLLFFSLGLLAELTLLEQMKPFALLIILLPTIFLAYRYGWQGGVLAS 240
              +  + + L+W LL F + L  +L L +++  F    + LP I LA+ YGWQG ++A+
Sbjct: 176 SQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIAT 235

Query: 241 SLNCILLATARQFSGSFSSDQELLIFMSSQAFVGLGLGIAISRQHQLALLLQKMNTRLAK 300
            +N I L  ++ +        +LL+ +  Q+  GL LG  I R       L+++N  L K
Sbjct: 236 LMNAIALIASQTWR---DHPVDLLLSLLVQSLTGLLLGAGIQR-------LRELNQSLQK 285

Query: 301 ELREKQDLARQLVSVEEQIRKSVARELHDEIGQNITAIQIQSMLAERLAS-NDQAKQAAS 359
           EL   Q LA +L+  EE +R+ VARELHD+IGQ ITAI+ Q+ + +RLA+ N   KQ+  
Sbjct: 286 ELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNASVKQSGQ 345

Query: 360 SVQSLAMRIHQSTRQLLKQLRPHILDELGLEHAIRQLVQEMRFAEQGMTVRLNMGVNPQK 419
            ++ L++ ++ + R+LL +LRP  LD+L LE AIR L++EM    +G+   L   ++   
Sbjct: 346 LIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESA 405

Query: 420 LDDTTRVTLYRIVQELLNNICKHAKATRVHISLFPGSE-MVLEVKDDGIGLPTDWRVRGH 478
           L +  RVTL+R+ QE LNNI KHA A+ V +  +   E ++L ++DDG GLP     +G 
Sbjct: 406 LSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQQGF 465

Query: 479 GLKGLSERVSALGGQLKMTSSTFQTGTRIIVNLPTK 514
           GL G+ ERV+ALGG L ++      GTR+ V+LP +
Sbjct: 466 GLTGMRERVTALGGTLHISC---LHGTRVSVSLPQR 498