Pairwise Alignments

Query, 784 a.a., ligand-gated channel from Vibrio cholerae E7946 ATCC 55056

Subject, 660 a.a., TonB-dependent heme/hemoglobin receptor ChuA/ShuA from Escherichia coli ECRC101

 Score = 53.5 bits (127), Expect = 4e-11
 Identities = 113/510 (22%), Positives = 184/510 (36%), Gaps = 117/510 (22%)

Query: 114 DIGIRGVQGEGRVPIFIDGSLQSTHTSRGYQGVSDRTYIDTDLLSSLTVNKGATIESSPY 173
           D+ +RG    G V + +DG  Q T T     G  + T++D  L+  + + +G +  +  Y
Sbjct: 88  DVNMRGYDHRG-VLVLVDGVRQGTDT-----GHLNGTFLDPALIKRVEIVRGPS--ALLY 139

Query: 174 ASGAVGGVVNATTLGIKDIIKDDQAFGVVLKARANNHNRTPDVSGDYSEQGQYALDERGE 233
            SGA+GGV++  T+  KD++++ Q+ G  +                      +     G+
Sbjct: 140 GSGALGGVISYDTVDAKDLLQEGQSSGFRV----------------------FGTGGTGD 177

Query: 234 HSAFKHGSLMLGLGYQA----ESFNTVLAYSKRSKGNHFAGKKGYEEYQEPVVGQGQEVV 289
           HS        LGLG  A    E+ + ++A+S R +G+                    E +
Sbjct: 178 HS--------LGLGASAFGRTENLDGIVAWSSRDRGD--------LRQSNGETAPNDESI 221

Query: 290 NTSFESDSWLFKLASDTGTAHNADFNYRHHAQKAGEVLMAYWYKSSEDWEGNPYPDGKDR 349
           N      +W         +A +     R++   A E       ++SE    NP  D    
Sbjct: 222 NNMLAKGTW------QIDSAQSLSGLVRYYNNDAREPKNPQTVEASE--SSNPMVD---- 269

Query: 350 MPQWGLGTAKVNTYSANYYYQPDHPWLNLNANFWYTEADL-AQYNGLWALGTNAEQYFHA 408
                  T + +   +       + WLN +A  +++E  + AQ  G  + G   EQ    
Sbjct: 270 -----RSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTG--SSGEYREQI--- 319

Query: 409 YHNDRSGLSLTNETLLTQWPVR---LNYGLAQQNERLSPEEDGQTRFTKTVTSRHGKRTA 465
                 G  L N + L         L YG     +   P                G  T 
Sbjct: 320 ----TKGARLENRSTLFADSFASHLLTYGGEYYRQEQHP---------------GGATTG 360

Query: 466 QNLFANADIDYSPLRVQLGLNLHNAKST-------DYQTKQQLDYK----EKLDLLSEFT 514
              F  A ID+S   +Q  + L +   T       D        YK    +K    +  T
Sbjct: 361 ---FPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMT 417

Query: 515 YALTPSTQLFLKSSRTYRMPSLYETTLSNEVFS----YNPY---NP-IKPEQAWNNEVGV 566
              T    LF   ++ +R P++ E    ++ FS    Y  Y   NP ++PE     E G 
Sbjct: 418 INPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGF 477

Query: 567 QFMASNSVLQDDRLNLSVSYFRNSIKDFIS 596
                + +L +D L    SYF    KD+IS
Sbjct: 478 GLRFDDLMLSNDALEFKASYFDTKAKDYIS 507