Pairwise Alignments

Query, 497 a.a., sensor histidine kinase KdpD from Vibrio cholerae E7946 ATCC 55056

Subject, 894 a.a., fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) from Escherichia coli BW25113

 Score =  172 bits (436), Expect = 4e-47
 Identities = 149/507 (29%), Positives = 235/507 (46%), Gaps = 42/507 (8%)

Query: 12  LILVALYAMVTVVGVMYRKDMIETDVAMLFLLLNILSASVLKPRNAYVMMGLSIIDYHYF 71
           ++  AL A++T++ + +       ++ ML+LL  ++ A       + V   ++++ +  F
Sbjct: 403 VVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVVATVINVVSFDLF 462

Query: 72  LLPDYQSFRFENAQYVITYAVLAFSGIFAVNITQAQRKQIEKNKRLQQQHKKYYELACHL 131
            +    +    + QY++T+AV+   G+   N+T   R Q    +  +Q+ +  YE++  L
Sbjct: 463 FIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYREQRTRHLYEMSKAL 522

Query: 132 SALSTSEDIAQATVKFLSKEKGIVSAIALYQPQWQWVAQHADFPVAAIELPQPPLTDNTS 191
           +   + +DIA  + +F++      S + L  P      Q    P         P  D  +
Sbjct: 523 AVGRSPQDIAATSEQFIASTFHARSQVLL--PDDNGKLQPLTHPQG-----MTPWDDAIA 575

Query: 192 TLVQDEQINAFTLVDRGTILGVIYF---LRYPHERFA----SPEALRRESKIAPWVRSLL 244
               D+ + A    D  T+ GV Y    L+   + +      P  LR +  I    R L 
Sbjct: 576 QWSFDKGLPAGAGTD--TLPGVPYQILPLKSGEKTYGLVVVEPGNLR-QLMIPEQQRLLE 632

Query: 245 TLSLARAHAHRTLAHVEAEKQL------ESTRTTLLASVSHDLKTPLGAIIGSATTLT-- 296
           T +L  A+A   L    +E+Q       E  R  LLA++SHDL+TPL  + G A  LT  
Sbjct: 633 TFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVLFGQAEILTLD 692

Query: 297 -----DPSLHLSTETQQELLTSIAEQGERLNRSLTKLLDITRYTASALVPKLDWVEPEEL 351
                 P    ++E +Q +L +         R +  LLD+ R  +     K +W+  EE+
Sbjct: 693 LASEGSPHARQASEIRQHVLNT--------TRLVNNLLDMARIQSGGFNLKKEWLTLEEV 744

Query: 352 IGTVLSRLAPRLTHHKVQIESQPM-LVELDSLLIEQVLINLVENAAKYTPRGSEIEIACA 410
           +G+ L  L P L+        +P+ L+ +D  L E+VLINL+ENA KY    +EI I   
Sbjct: 745 VGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAH 804

Query: 411 YQEQQFTLAVMDNGAGIPDEALPRIFDRFYRVEGNHA-DGTGLGLAICQVIVAAHQGSIR 469
            + +   L V DNG G+P      IFD+F R     A  G GLGLAIC+ IV  H G+I 
Sbjct: 805 VEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIVDVHGGTIT 864

Query: 470 VHNRESGGACFTVTIPCRQYNLKELYE 496
             NR  GGACF VT+P  Q    EL E
Sbjct: 865 AFNRPEGGACFRVTLP--QQTAPELEE 889