Pairwise Alignments

Query, 468 a.a., ClC family H(+)/Cl(-) exchange transporter from Vibrio cholerae E7946 ATCC 55056

Subject, 473 a.a., chloride channel protein (NCBI) from Escherichia coli BW25113

 Score =  504 bits (1297), Expect = e-147
 Identities = 247/442 (55%), Positives = 323/442 (73%)

Query: 17  KDVINQFLSKDKTPFSVLFLSLLVGILAGLVGTYFEQAVHLVSETRTDWLKSEIGSFLPL 76
           + +I Q L +DKTP ++LF++ +VG L GL    F++ V  +   R   L     ++  L
Sbjct: 19  RQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLL 78

Query: 77  WLAAFLISAFLAFIGYFLVHRFAPEAAGSGIPEIEGAMDGMRPVRWWRVLPVKFFGGMGA 136
              AFL SA LA  GYFLV ++APEA GSGIPEIEGA++  RPVRWWRVLPVKFFGG+G 
Sbjct: 79  LTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGT 138

Query: 137 LGSGMVLGREGPTVQMGGAVGRMISDIFRVKNEDTRHSLLAAGAAGGLAAAFNAPLAGIM 196
           LG GMVLGREGPTVQ+GG +GRM+ DIFR+K ++ RH+LLA GAA GLAAAFNAPLAGI+
Sbjct: 139 LGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGIL 198

Query: 197 FVIEEMRPQFRYTLISVRAVIISAVAANIVFRVINGQDAVITMPQYDAPELSTLGLFLLL 256
           F+IEEMRPQFRYTLIS++AV I  + + I++R+ N + A+I + +     L+TL L+L+L
Sbjct: 199 FIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLIL 258

Query: 257 GALFGVFGVLFNYLITLAQDLFVKFHRNDRKRYLLTGSMIGGCFGLLLLYVPELTGGGIS 316
           G +FG+FG +FN  +   QDL  + H  +  +++L G  IGG  GLL    P  +GGG +
Sbjct: 259 GIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFN 318

Query: 317 LIPTITNGGYGAGILLLLFVGRIFTTLLCFGSGAPGGIFAPMLALGTLFGYAFGLIAKMW 376
           LIP  T G +  G+L+ +FV R+ TTLLCF SGAPGGIFAPMLALGT+ G AFG++A   
Sbjct: 319 LIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVEL 378

Query: 377 FPELNIEPGMFAIAGMGALFAATVRAPITGILLVIEMTNNYHLILPLIITSLGAVIFAQL 436
           FP+ ++E G FAIAGMGAL AA++RAP+TGI+LV+EMT+NY LILP+IIT LGA + AQ 
Sbjct: 379 FPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQF 438

Query: 437 LGGQPIYSQLLHRTLKNQKLQQ 458
            GG+P+YS +L RTL  Q+ +Q
Sbjct: 439 TGGKPLYSAILARTLAKQEAEQ 460