Pairwise Alignments

Query, 468 a.a., ClC family H(+)/Cl(-) exchange transporter from Vibrio cholerae E7946 ATCC 55056

Subject, 418 a.a., voltage-gated ClC-type chloride channel ClcB from Escherichia coli ECRC62

 Score =  134 bits (337), Expect = 6e-36
 Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 9/319 (2%)

Query: 128 VKFFGGMGALGSGMVLGREGPTVQMGGAVGRMISDIFRVKNEDTRHSLLAAGAAGGLAAA 187
           VK    +  + SG  +GREG  + +        +  F  + E      +A GAA G+AAA
Sbjct: 102 VKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQE--WKLWIACGAAAGMAAA 159

Query: 188 FNAPLAGIMFVIEEMRPQFRYTLISVRAVIISAVAANIVFRVINGQDAVITMPQYDAP-E 246
           + APLAG +F+ E +       L S+  VIISAV A +V  +IN  DA++   Q     +
Sbjct: 160 YRAPLAGSLFIAEVLFGTMM--LASLGPVIISAVVALLVSNLINHSDALLYNVQLSVTVQ 217

Query: 247 LSTLGLFLLLGALFGVFGVLFNYLITLAQDLFVKFHRNDRKRYLLTGSMIGGCFGLLLLY 306
                L +  G L G+ G L   L+      FV        +  L G +I    GLL L+
Sbjct: 218 ARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLAL-GELI---VGLLSLF 273

Query: 307 VPELTGGGISLIPTITNGGYGAGILLLLFVGRIFTTLLCFGSGAPGGIFAPMLALGTLFG 366
            P + G G S + +         I+  +F+ ++   L   GSGAPGG+F P L +G   G
Sbjct: 274 TPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIG 333

Query: 367 YAFGLIAKMWFPELNIEPGMFAIAGMGALFAATVRAPITGILLVIEMTNNYHLILPLIIT 426
             +G    +WF +      +  + GM  L AAT  API   L++ EMT  Y L+  L+I 
Sbjct: 334 MLYGRSLGLWFTDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIA 393

Query: 427 SLGAVIFAQLLGGQPIYSQ 445
            + A + ++ L    IY Q
Sbjct: 394 CVIASVISRTLHRDSIYRQ 412