Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 702 a.a., bifunctional (p)ppGpp synthase/hydrolase from Pseudomonas putida KT2440

 Score =  764 bits (1973), Expect = 0.0
 Identities = 368/703 (52%), Positives = 511/703 (72%), Gaps = 9/703 (1%)

Query: 5   DSLKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLE 64
           ++L +    YL   Q+  +R++Y  A  AH+GQ R SGEPY+ HP+AVA ILA+M +D +
Sbjct: 5   EALAERLSTYLGPEQVNLVRRAYFYAEQAHDGQRRRSGEPYVTHPLAVASILADMHMDHQ 64

Query: 65  TLQAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVL 124
           +L AA+LHDVIED  + KE L   FG +VAELVDGVSKL ++ F  + EAQAENF+KM +
Sbjct: 65  SLMAAMLHDVIEDTGIAKEALSQQFGETVAELVDGVSKLTQMNFETKAEAQAENFQKMAM 124

Query: 125 AMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEE 184
           AM +DIRVIL+KLADR HNMRTL  L  +K+RRIA+ETLEIYAP+A+RLG+H ++ E E+
Sbjct: 125 AMARDIRVILVKLADRLHNMRTLEVLSGEKRRRIAKETLEIYAPIANRLGMHTVRVEFED 184

Query: 185 LGFEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVGLPARVVGREKNLFSIY 244
           LGF+A++P R  ++   VK+ARGNRKE++ +I   +   L   G+   V GR+K+L+ IY
Sbjct: 185 LGFKAMHPMRSSLIHRAVKSARGNRKEIVAKIEHSLANCLAADGIEGEVSGRQKHLYGIY 244

Query: 245 NKMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQ 304
            KM+ K + F+ IMD+YAFRI+VD  DTCYRVLG VH+LYKP P R KDYIA+PKANGYQ
Sbjct: 245 KKMRGKRRAFNEIMDVYAFRIIVDKVDTCYRVLGAVHNLYKPLPGRFKDYIAIPKANGYQ 304

Query: 305 SLHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYKANSERGGTTAQIKAQRWMQSLL 364
           SLHT++ G HGVP+E+QIRT +M++MA+ G+AAHW YK+N +     +  +A++W++ +L
Sbjct: 305 SLHTTLFGMHGVPIEIQIRTREMEEMANNGIAAHWLYKSNDDEQPKGSHARARQWVKGIL 364

Query: 365 ELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTCVG 424
           ELQQ AGNS EFIE+VK DLFPDE+YVFTPKGRI+ELP G+TAVDFAYAVHTD+GN+C+ 
Sbjct: 365 ELQQRAGNSLEFIESVKIDLFPDEVYVFTPKGRIMELPKGSTAVDFAYAVHTDVGNSCIA 424

Query: 425 ARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREDSI 484
            R++R   PLS+ L+SG TVEI+SAPGARPN AWLN+VV+ +ART IR  LK  RR +SI
Sbjct: 425 CRINRRLAPLSEPLQSGSTVEIVSAPGARPNPAWLNFVVSGKARTNIRHALKQQRRSESI 484

Query: 485 TLGRRLLNHALG--EHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIARRLL 542
           +LG RLLN  L   + S+ +I  E I  +L++ ++  ++DLL  IGLG  M+ V+ARRLL
Sbjct: 485 SLGERLLNKVLTGFDSSLEKIPQERIQSILAEYRLELIEDLLEDIGLGNRMAYVVARRLL 544

Query: 543 -GNADELTEPSKSGGNKNKLPIRGAEGILLTFANCCHPIPDDHIIAHVSPGRGLVVHRET 601
               ++L  P      +  L IRG EG++L++A CC PIP D I+ H+S G+G+VVH E 
Sbjct: 545 SAEGEQLPAP------EGPLAIRGTEGLVLSYAKCCTPIPGDPIVGHLSAGKGMVVHLEN 598

Query: 602 CPNVRGYQKEPDKYMAVEWTKDYDQEFITELKVDMHNRQGALAELTNVISKTGSNIHGLS 661
           C N+   +  P+K + + W KD   EF  EL+V++ +++G +A L + ++    NI  +S
Sbjct: 599 CRNISEIRHNPEKCVQLSWAKDITGEFNVELRVELEHQRGLIALLASSVNAADGNIEKIS 658

Query: 662 TEERDGRLYTVTVLLTTKDRVHLAGIMRKIRTMPHALKVRRRK 704
            +ERDGR+  V ++++  DRVHLA +++K+RT+   +++ R +
Sbjct: 659 MDERDGRISVVQLVVSVHDRVHLARVIKKLRTLTGVVRITRMR 701