Pairwise Alignments

Query, 705 a.a., bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase from Vibrio cholerae E7946 ATCC 55056

Subject, 744 a.a., GTP pyrophosphohydrolase/synthetase, RelA/SpoT family from Agrobacterium fabrum C58

 Score =  445 bits (1144), Expect = e-129
 Identities = 253/695 (36%), Positives = 384/695 (55%), Gaps = 41/695 (5%)

Query: 7   LKDVAQEYLTEPQIEALRQSYVVARDAHEGQTRSSGEPYIIHPVAVARILAEMRLDLETL 66
           L +  Q+Y  +     L ++YV A   H  Q R++G+PYI HP+ VA IL EM LD  T+
Sbjct: 7   LVERVQKYKPDANEALLNKAYVYAMQKHGQQKRANGDPYISHPLEVAAILTEMHLDESTI 66

Query: 67  QAALLHDVIEDCDVTKEDLDAHFGSSVAELVDGVSKLDKLKFRDRKEAQAENFRKMVLAM 126
             ALLHD IED   T+ ++D  FG  +  LV+G++KL KL    RK  QAEN RK++LA+
Sbjct: 67  AVALLHDTIEDTTATRAEIDELFGEDIGRLVEGLTKLKKLDLVTRKAKQAENLRKLLLAI 126

Query: 127 VQDIRVILIKLADRTHNMRTLGALRPDKKRRIARETLEIYAPLAHRLGIHNIKTELEELG 186
             D+RV+L+KLADR HNMRT+  +  DK+ RI+ ET+EIYAPLA R+G+ +++ ELE+L 
Sbjct: 127 SDDVRVLLVKLADRLHNMRTMEYMPADKRSRISEETMEIYAPLAGRMGMQDMRDELEDLS 186

Query: 187 FEALYPNRYRVLKEVVKAARGNRKEMIQRIHSEIEGRLQEVG-LPARVVGREKNLFSIYN 245
           F  L P  Y  +   +       + +I++I  E+   L   G L   V GR+K  +S++ 
Sbjct: 187 FRYLNPEAYETVTNRLLELETRNEGLIKKIEDELRELLVANGLLGTHVKGRQKKPYSVFR 246

Query: 246 KMKTKEQRFHTIMDIYAFRIVVDTADTCYRVLGQVHSLYKPRPARMKDYIAVPKANGYQS 305
           KM++K   F  + D+Y FRI+VD    CYR LG VH+ ++  P R KDYI+ PK N Y+S
Sbjct: 247 KMQSKSLSFEQLSDVYGFRILVDDIPGCYRALGIVHTRWRVVPGRFKDYISTPKQNDYRS 306

Query: 306 LHTSMVGPHGVPVEVQIRTEDMDQMADKGVAAHWSYK--ANSERGGTTAQIKAQRWMQSL 363
           +HT++VGP    +E+QIRT+ M ++A+ G+AAH  YK   N E    + +  A  W++  
Sbjct: 307 IHTTIVGPSRQRIELQIRTKRMHEIAEFGIAAHALYKDGENGEGDLLSKESNAYSWLRHT 366

Query: 364 LELQQSAGNSFEFIENVKSDLFPDEIYVFTPKGRIVELPMGATAVDFAYAVHTDIGNTCV 423
           +E      +  EF+E+ K +LF D+++ FTPKG+++ LP GAT +DFAYAVHT+IG+T V
Sbjct: 367 IESLAEGDSPEEFLEHTKLELFQDQVFCFTPKGKLIALPRGATPIDFAYAVHTNIGDTTV 426

Query: 424 GARVDRTPYPLSQSLKSGQTVEIISAPGARPNAAWLNYVVTSRARTKIRQVLKTMRREDS 483
           GA+++    PL   L +G  VEII +    P AAW   VVT +AR+ IR+  +   R+  
Sbjct: 427 GAKINGRIMPLVTRLNNGDEVEIIRSGVQVPPAAWEEVVVTGKARSAIRRATRMAIRKQY 486

Query: 484 ITLGRRLLNHALGEHSVNEIAPENISKVLSDLKIASMDDLLAAIGLGELMSIVIAR---- 539
             LG R+L     E +    + E +  VL  L    ++D +AA+G GE+ S+ + R    
Sbjct: 487 SGLGYRILERTF-ERAGKAFSREALKPVLHRLAQKDVEDAIAAVGRGEVSSLDVLRAVFP 545

Query: 540 ---------RLLGNADELTEPSKSG----------------------GNKNKLPIRGAEG 568
                    ++ G+       S SG                         + LPIRG  G
Sbjct: 546 DYQDERVTVKMTGDDGWFNMRSASGMVFKIPGKSRSVLEDDGAAEMLDGPDPLPIRGLSG 605

Query: 569 ILLTFANCCHPIPDDHIIAHVSPGRGLVVHRETCPNVRGYQKEPDKYMAVEWTKD--YDQ 626
            +    +    +P D I+  +  G+G+ ++    P ++ +  EP++++ V W  D     
Sbjct: 606 NVDVHFSAAGAVPGDRIVGIMEKGKGITIYPIQAPALQRFDDEPERWIDVRWDLDEANKS 665

Query: 627 EFITELKVDMHNRQGALAELTNVISKTGSNIHGLS 661
            F+  + ++  N  G LA +   I+    NI GL+
Sbjct: 666 RFMARVMINALNEPGTLASVAQSIATLDVNIRGLN 700