Pairwise Alignments

Query, 803 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Vibrio cholerae E7946 ATCC 55056

Subject, 820 a.a., bifunctional aspartate kinase/homoserine dehydrogenase I from Escherichia coli ECRC62

 Score =  353 bits (907), Expect = e-101
 Identities = 254/826 (30%), Positives = 427/826 (51%), Gaps = 58/826 (7%)

Query: 9   KFGGSSLADPECYQRVAKILKSYSKSDDLV-VVSAAGKTTNRLISFVEALSKDGRVAHET 67
           KFGG+S+A+ E + RVA IL+S ++   +  V+SA  K TN L++ +E  +  G+ A   
Sbjct: 5   KFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEK-TISGQDALPN 63

Query: 68  LHALRQYQSELITKLLSNEAAEPL-------------LSQLQQEISVLGELTAPLSNAQY 114
           +    +  +EL+T L + +   PL             +  +   IS+LG+    ++ A  
Sbjct: 64  ISDAERIFAELLTGLTAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAA-- 121

Query: 115 AWVLGHGELWSARLLAALLNQQDLPAVAQD-ARTFLRAEAGTQPEVDRARSYPLLKA--V 171
             ++  GE  S  ++A +L  +       D     L      +  VD A S   + A  +
Sbjct: 122 --LICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRI 179

Query: 172 LAQHTQRRVVITGFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSAD 231
            A H    V++ GF A NE+G+ V+LGRNGSDYSA V+ A        IW+DV GVY+ D
Sbjct: 180 PADHM---VLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCD 236

Query: 232 PRIVSDACLLPLLRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPES-----G 286
           PR V DA LL  +   EA EL+   A VLH RT+ P+AQ  +   ++ +  P++     G
Sbjct: 237 PRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIG 296

Query: 287 STRIERVLASGRGAKIITSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQ 346
           ++R E  L      K I++L+++ +  +S         +   V   + R ++  +     
Sbjct: 297 ASRDEDELP----VKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQS 352

Query: 347 PDQYRLRLAYTAEIAPGAFAALQDAAFEAEIKLKEGY----------DLIAAVGAGVTKN 396
             +Y +           A  A+Q+   E  ++LKEG            +I+ VG G+   
Sbjct: 353 SSEYSISFCVPQSDCVRAERAMQE---EFYLELKEGLLEPLAVTERLAIISVVGDGMRTL 409

Query: 397 PNHCYGFYQQLNALPVEFISASESSL--SLVAVLRQTPIHSLVNAIHKQLFQAQKHVAIA 454
                 F+  L    +  ++ ++ S   S+  V+      + V   H+ LF   + + + 
Sbjct: 410 RGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVF 469

Query: 455 LCGKGNIGSSWLKLFAEQKEKLEQRHGMNFELVAVVDSQTYWFNEQGINPNQVATHFQDE 514
           + G G +G + L+    Q+  L+ +H ++  +  V +S+    N  G+N      ++Q+E
Sbjct: 470 VIGVGGVGGALLEQLKRQQSWLKNKH-IDLRVCGVANSKALLTNVHGLN----LENWQEE 524

Query: 515 ALPNQEQSWLKKLGAL-EGYD--EAVVIDVTASEELAEQYLDIAEHGLHLISANKVAGSA 571
               +E   L +L  L + Y     V++D T+S+ +A+QY D    G H+++ NK A ++
Sbjct: 525 LAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTS 584

Query: 572 AGNYYYQVKDAFHKIGRHWLYNATVGAGLPINHTVRDLRESGDDIMALSGIFSGTLSWLF 631
           + +YY+ ++ A  K  R +LY+  VGAGLP+   +++L  +GD++M  SGI SG+LS++F
Sbjct: 585 SMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIF 644

Query: 632 QQYDGSLPFSELVDLAWQQGLTEPDPRCDLDGSDVMRKLVILARESGLEIEPQNVKVESL 691
            + D  + FSE   LA + G TEPDPR DL G DV RKL+ILARE+G E+E  ++++E +
Sbjct: 645 GKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPV 704

Query: 692 VPAELRSV-SLDDFLDNSKLLNEQLAERLARAQKQGKVLRYVARLEKNGKASVGVEALEQ 750
           +PAE  +   +  F+ N   L++  A R+A+A+ +GKVLRYV  ++++G   V +  ++ 
Sbjct: 705 LPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEGKVLRYVGNIDEDGACRVKIAEVDG 764

Query: 751 DHPLANLLPCDNIFAIESKWYRDNPLVIRGPGAGREVTAGAIQSDL 796
           + PL  +   +N  A  S +Y+  PLV+RG GAG +VTA  + +DL
Sbjct: 765 NDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAGNDVTAAGVFADL 810