Pairwise Alignments

Query, 803 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Vibrio cholerae E7946 ATCC 55056

Subject, 810 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Escherichia coli ECRC62

 Score =  939 bits (2428), Expect = 0.0
 Identities = 478/803 (59%), Positives = 600/803 (74%), Gaps = 8/803 (0%)

Query: 5   RQLHKFGGSSLADPECYQRVAKILKSYSKSDDLVVVSAAGKTTNRLISFVEALSKDGRVA 64
           RQLHKFGGSSLAD +CY RVA I+  YS+ DD++VVSAAG TTN+LI++++    D   A
Sbjct: 12  RQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLINWLKLSQTDRLSA 71

Query: 65  HETLHALRQYQSELITKLLSNEAAEPLLSQLQQEISVLGELT-APLSNAQYAWVLGHGEL 123
           H+    LR+YQ +LI+ LL  E A+ L+S    ++  L  L  + +++A YA V+GHGE+
Sbjct: 72  HQVQQTLRRYQCDLISGLLPAEEADSLISAFVSDLERLAALLDSGINDAVYAEVVGHGEV 131

Query: 124 WSARLLAALLNQQDLPAVAQDARTFLRAEAGTQPEVDRARSYPLLKAVLAQHTQRRVVIT 183
           WSARL++A+LNQQ LPA   DAR FLRAE   QP+VD   SYPLL+ +L QH  +R+V+T
Sbjct: 132 WSARLMSAVLNQQGLPAAWLDAREFLRAERAAQPQVDEGLSYPLLQQLLVQHPGKRLVVT 191

Query: 184 GFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSADPRIVSDACLLPL 243
           GF+++N  G+TVLLGRNGSDYSAT IGALA VSRVTIWSDVAGVYSADPR V DACLLPL
Sbjct: 192 GFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADPRKVKDACLLPL 251

Query: 244 LRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPESGSTRIERVLASGRGAKII 303
           LRLDEA+ELARLAAPVLH+RTLQPV+ S ++L LRCS+ P+ GSTRIERVLASG GA+I+
Sbjct: 252 LRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIV 311

Query: 304 TSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQPDQYRLRLAYTAEIAPG 363
           TS DDV LIE       DF+   +++ Q L+R Q++PL      D+  L+  YT+E+A  
Sbjct: 312 TSHDDVCLIEFQVPASQDFKLAHKEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADS 371

Query: 364 AFAALQDAAFEAEIKLKEGYDLIAAVGAGVTKNPNHCYGFYQQLNALPVEFISASESSLS 423
           A   L +A    E++L++G  L+A VGAGVT+NP HC+ F+QQL   PVEF   S+  +S
Sbjct: 372 ALKILDEAGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGIS 431

Query: 424 LVAVLRQTPIHSLVNAIHKQLFQAQKHVAIALCGKGNIGSSWLKLFAEQKEKLEQRHGMN 483
           LVAVLR  P  SL+  +H+ +F+A+K + + L GKGNIGS WL+LFA ++  L  R G  
Sbjct: 432 LVAVLRTGPTESLIQGLHQSVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFE 491

Query: 484 FELVAVVDSQTYWFNEQGINPNQVATHFQDEALPNQEQS---WLKKLGALEGYDEAVVID 540
           F L  VVDS+    +  G++ ++    F DEA+   E+S   W++       YD+ VV+D
Sbjct: 492 FVLAGVVDSRRSLLSYDGLDASRALAFFNDEAVEQDEESLFLWMR----AHPYDDLVVLD 547

Query: 541 VTASEELAEQYLDIAEHGLHLISANKVAGSAAGNYYYQVKDAFHKIGRHWLYNATVGAGL 600
           VTAS++LA+QYLD A HG H+ISANK+AG++  N Y Q+ DAF K GRHWLYNATVGAGL
Sbjct: 548 VTASQQLADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGL 607

Query: 601 PINHTVRDLRESGDDIMALSGIFSGTLSWLFQQYDGSLPFSELVDLAWQQGLTEPDPRCD 660
           PINHTVRDL +SGD I+++SGIFSGTLSWLF Q+DGS+PF+ELVD AWQQGLTEPDPR D
Sbjct: 608 PINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDD 667

Query: 661 LDGSDVMRKLVILARESGLEIEPQNVKVESLVPAELRSVSLDDFLDNSKLLNEQLAERLA 720
           L G DVMRKLVILARE+G  IEP  V+VESLVPA     S+D F +N   LNEQ+ +RL 
Sbjct: 668 LSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLE 727

Query: 721 RAQKQGKVLRYVARLEKNGKASVGVEALEQDHPLANLLPCDNIFAIESKWYRDNPLVIRG 780
            A++ G VLRYVAR + NGKA VGVEA+ +DHPLA+LLPCDN+FAIES+WYRDNPLVIRG
Sbjct: 728 AAREMGLVLRYVARFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRG 787

Query: 781 PGAGREVTAGAIQSDLNLLASLL 803
           PGAGR+VTAGAIQSD+N LA LL
Sbjct: 788 PGAGRDVTAGAIQSDINRLAQLL 810