Pairwise Alignments

Query, 803 a.a., bifunctional aspartate kinase/homoserine dehydrogenase II from Vibrio cholerae E7946 ATCC 55056

Subject, 821 a.a., Aspartokinase I/homoserine dehydrogenase I from Alteromonas macleodii MIT1002

 Score =  332 bits (852), Expect = 4e-95
 Identities = 242/819 (29%), Positives = 396/819 (48%), Gaps = 44/819 (5%)

Query: 9   KFGGSSLADPECYQRVAKILKSYSKSDDLVVVSAAGKTTNRLISFVEALSKDGRVAHETL 68
           KFGGSSLAD   Y RV +I  +  ++D   VV +A K     +S    L  +   A E  
Sbjct: 5   KFGGSSLADAPRYMRVMEISTATHQTDGAAVVLSAPKGVTNALS----LLCEQAAAGEDF 60

Query: 69  HALRQYQSELITKLLSN--------------EAAEPLLSQLQQEISVLGELTAPLSNAQY 114
             L    ++ +T + +N              E     LS L+Q +  +  L     N   
Sbjct: 61  QPLFNKLNDTVTGIANNLNEELDGFAHASVVEFINSHLSVLKQHLEGIKLLGVAPDNVA- 119

Query: 115 AWVLGHGELWSARLLAALLNQQDLPAVAQDARTFLRAEAGTQPEVDRARSYPLLKAVLAQ 174
           A +L  GE  S  L +A+L+ + +     D   ++ AE      +D      L KA  + 
Sbjct: 120 AGILSIGEYISVTLFSAMLSAKGIANRVIDPVKYVLAEGDY---LDSIADVSLSKARFSD 176

Query: 175 ---HTQRRVVITGFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSAD 231
                   +V+ GF+A NE G+ V LGRNGSDYSA ++ A  + +   IW+DV GVY+AD
Sbjct: 177 VPTDGSEFLVMPGFVAANEAGEKVTLGRNGSDYSAAILAACIDANCCEIWTDVDGVYNAD 236

Query: 232 PRIVSDACLLPLLRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPESGSTRIE 291
           P  V  A LL  L   EA EL+   A VLH +T+ P+AQ  +   +R +  P +  T I 
Sbjct: 237 PNQVEGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQHHIPCLIRNTLNPAAPGTLIS 296

Query: 292 RVLAS-GRGAKIITSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQPDQY 350
              +      K I+ LD+V +  ++         +   V + +    +          +Y
Sbjct: 297 NEKSEVWTSVKGISQLDNVTMFNVAGPGLKGMVGMASRVFEVMSNANISISLITQSSSEY 356

Query: 351 RLRLAYTAEIAPGAFAALQDA-AFEAE------IKLKEGYDLIAAVGAGVTKNPNHCYGF 403
            +     ++ A  A   L+DA A E +      I+++    ++  VG G+ +       F
Sbjct: 357 SISFCIQSKDASRALTLLEDAFALELQNQLLDPIEVRHDLAIVTLVGDGMRQTKGLAARF 416

Query: 404 YQQLNALPVEFISASESSL--SLVAVLRQTPIHSLVNAIHKQLFQAQKHVAIALCGKGNI 461
           +  L    V  ++ ++ S   S+  V+        V  IH+  F  +  + + L G GN+
Sbjct: 417 FNSLAQARVNNVAIAQGSSERSISTVIESKRAKKAVKVIHQNFFSDRHTIDVFLVGCGNV 476

Query: 462 GSSWLKLFAEQKEKLEQRHGMNFELVAVVDSQTYWFNEQGINPN---QVATHFQDEALPN 518
           G+  L    +Q+  L +R+ +   +  + +S+    N QGI+ +   + A     E L  
Sbjct: 477 GTELLGQIEKQQPALLKRN-VQLRVYGIANSRKLLLNSQGIDLSGDWKAALESVSEGLSV 535

Query: 519 QEQSWLKKLGALEGYDEAVVIDVTASEELAEQYLDIAEHGLHLISANKVAGSAAGNYYYQ 578
           +    L +          V++D T+ E +A+QY+D+ E G H+++ NK A ++A +YY +
Sbjct: 536 ER---LHQFANDNSLVNPVIVDCTSHEAIAQQYVDMMESGFHVVTPNKKANTSAMSYYRK 592

Query: 579 VKDAFHKIGRHWLYNATVGAGLPINHTVRDLRESGDDIMALSGIFSGTLSWLFQQYDGSL 638
           ++       R +LY  TVGAGLP+   ++ L  +GD +    GI SG+LS++F + +  +
Sbjct: 593 LRKTAQSTNRQYLYETTVGAGLPVIDNLQKLFSAGDTLHRFEGILSGSLSYVFGKLEEGM 652

Query: 639 PFSELVDLAWQQGLTEPDPRCDLDGSDVMRKLVILARESGLEIEPQNVKVESLVPAEL-R 697
             S+    A   G TEPDPR DL G DV RKL+I+ARE+ L +E  ++++ES++P     
Sbjct: 653 SLSQATQTAKDNGFTEPDPRDDLSGMDVARKLLIMAREADLALELSDIEIESVLPEGFAE 712

Query: 698 SVSLDDFLDNSKLLNEQLAERLARAQKQGKVLRYVARLEKNGKASVGVEALEQDHPLANL 757
             S+D+F+     L+    E++  A+ +GKVLRY+  +E +GK  V ++A+   +PL+ +
Sbjct: 713 DCSIDEFMQQLPELDASFGEKVEAAKAEGKVLRYIGSIE-DGKCRVSIQAVPASNPLSQV 771

Query: 758 LPCDNIFAIESKWYRDNPLVIRGPGAGREVTAGAIQSDL 796
              +N  AI S +Y   P VIRG GAG  VTA  + +D+
Sbjct: 772 KDGENALAINSDYYSPIPYVIRGYGAGGTVTAAGVFADI 810