Pairwise Alignments

Query, 425 a.a., malate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 759 a.a., NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase from Escherichia coli ECRC100

 Score =  457 bits (1176), Expect = e-133
 Identities = 237/411 (57%), Positives = 302/411 (73%), Gaps = 2/411 (0%)

Query: 12  EEQFRQRALDYHAYPTAGKIGIALTKPADSAADLALAYSPGVAEPVREIAQNVDNVYKYT 71
           ++Q +Q ALD+H +P  GKI ++ TKP  +  DLALAYSPGVA P  EI ++    YKYT
Sbjct: 2   DDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVAAPCLEIEKDPLKAYKYT 61

Query: 72  AKGNTVAVISNGTAILGLGNLGPMASKPVMEGKALLFKRFAGLDSIDIEVKHRTIDEFID 131
           A+GN VAVISNGTA+LGLGN+G +A KPVMEGK +LFK+FAG+D  DIEV     D+FI+
Sbjct: 62  ARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFAGIDVFDIEVDELDPDKFIE 121

Query: 132 TVANIADTFGGINLEDIKAPDCFEIERRLIERCDVPVFHDDQHGTAIVTAAGMLNALELQ 191
            VA +  TFGGINLEDIKAP+CF IE++L ER ++PVFHDDQHGTAI++ A +LN L + 
Sbjct: 122 VVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFHDDQHGTAIISTAAILNGLRVV 181

Query: 192 GKQLKDCIIVCLGAGAAAVACMELLIKCGAMREKIYMLDRKGVIHTRRD-DLNEYKALFA 250
            K + D  +V  GAGAAA+ACM LL+  G  +  I + D KGVI+  R+ ++ E KA +A
Sbjct: 182 EKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVVCDSKGVIYQGREPNMAETKAAYA 241

Query: 251 NNTD-KRTLEDVIAGADLFLGVSGPNLLPADALKLMADKPVVFACSNPDPEIKPEIAHQV 309
              D KRTL+DVI GAD+FLG SGP +L  + +K MA  P++ A +NP+PEI P +A +V
Sbjct: 242 VVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKKMARAPMILALANPEPEILPPLAKEV 301

Query: 310 RNDMIMGTGRSDYPNQVNNVLCFPFIFRGALDVRASEINDQMKLAAVEAIRQLAKEPVPA 369
           R D I+ TGRSDYPNQVNNVLCFPFIFRGALDV A+ IN++MKLAAV AI +LA      
Sbjct: 302 RPDAIICTGRSDYPNQVNNVLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQSE 361

Query: 370 EVLAAAGVDKLSFGIDYIIPKPMDPRLLPRVARAVAEAAVESGVARIPMPE 420
            V +A G   LSFG +YIIPKP DPRL+ ++A AVA+AA+ESGVA  P+ +
Sbjct: 362 VVASAYGDQDLSFGPEYIIPKPFDPRLIVKIAPAVAKAAMESGVATRPIAD 412