Pairwise Alignments

Query, 953 a.a., valine--tRNA ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 938 a.a., Isoleucyl-tRNA synthetase (EC 6.1.1.5) from Enterobacter asburiae PDN3

 Score =  125 bits (315), Expect = 1e-32
 Identities = 163/802 (20%), Positives = 288/802 (35%), Gaps = 162/802 (20%)

Query: 41  PPNVTGSLHMGHAFQDTIMDTLIRCQRMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGK 100
           PP   GS+H+GH+    + D +++ + + G ++ +  G D  G+     +E K+  E GK
Sbjct: 57  PPYANGSIHIGHSVNKILKDIIVKSKGLTGYDSPYVPGWDCHGLP----IELKVEQEFGK 112

Query: 101 TKHDYGRDAFIDKIWEWKAESGGTITKQLRRLGASVDWDRERFTMDDGFYKAVQEVFVRL 160
               +    F  K  E+ A           RLG   DW     TMD      +     ++
Sbjct: 113 PGEKFTAAEFRAKCREYAATQVDGQRADFIRLGVLGDWSHPYLTMDFKTEANIIRALGKI 172

Query: 161 YKDDLIYRGKRLVNWDPKLHTAISDLEVENKETKGHMWHFRYPLAD--------GVKTAD 212
             +  +++G + V+W     +A+++ EVE  +         +   D        GV + +
Sbjct: 173 IGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFHAVDQDAVKAKFGVSSVN 232

Query: 213 GKDYIVVATTRPETMLGDTGVAVNPE-DPRYKDLIGKEIIL------------------- 252
           G   +V+ TT P T+  +  ++++ E +     + G+ +IL                   
Sbjct: 233 GPISLVIWTTTPWTLPANRAISLSGEFEYALVQIDGQAVILAKDLVESVLKRAHITDYTV 292

Query: 253 ----------------PIVGRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHQLP 296
                           P +   +P +  +H  +E GTG V     H  +DY +  ++ L 
Sbjct: 293 LGTLKGDALELMRFKHPFLDFDVPAILGDHVTLEAGTGAVHTAGGHGPDDYNISLKYGLE 352

Query: 297 MINILTFDANIRDAAEVFNSNGEASNAYGTEIPAKY---QGMERFAARKAIVAEFEELGL 353
           + N +  D                    G+ +P  Y    G+  F A   IV      G 
Sbjct: 353 IANPVGPD--------------------GSYLPGTYPALDGINVFKANDIIVDMLRTSGA 392

Query: 354 LQEIKDHDLTVPYGDRGGVVIEPMLTDQWYVRAGILAKPAVEAVENGDIQFVPKQYENMY 413
           L  ++    + P   R    I    T QW+V             E   +Q++P   +   
Sbjct: 393 LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLREQSLKEIKGVQWIPDWGQARI 452

Query: 414 FSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVFVGRNEEEVRAEN-NIAADVALRQD--- 469
            S + +  DWCISRQ  WG  +P       ++FV +  +E+      +  +VA R +   
Sbjct: 453 ESMVANRPDWCISRQRTWG--VPM------SLFVHKETQELHPNTLELMEEVAKRVEVDG 504

Query: 470 -----------------------DDVLDTWFSSALWTFGTLGWPEKTPELKVFHPTDVLV 506
                                   D LD WF S       +   +  PE    H  D+ +
Sbjct: 505 IQAWWDLDSRDILGADADNYEKVPDTLDVWFDSGSTHSSVV---DVRPEF-AGHAADMYL 560

Query: 507 TGFDIIFFWVARMIMMTMHFCKDEDGKAQVPFKTVYVTGLIRDENGDKMSKSKGNVLDPI 566
            G D    W    +M++         K + P++ V   G   D  G KMSKS GN + P 
Sbjct: 561 EGSDQHRGWFMSSLMISTAM------KGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQ 614

Query: 567 DMIDGIDLESLVAKRTGNMMQPQLAAKIEKNTRKTFENGIEAYGTDSLRFTLAAMASTGR 626
           D+++ +                                     G D LR  +A+   TG 
Sbjct: 615 DVMNKL-------------------------------------GADILRLWVASTDYTGE 637

Query: 627 DINWD--MKR-LEGYRNFCNKLWNASRYVLMNTEEQDCGFAAGAELEYSLADKWIESQFE 683
               D  +KR  + YR    ++ N +R++L N    D         E  + D+W     +
Sbjct: 638 MAVSDEILKRAADSYR----RIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAK 693

Query: 684 LAAKEFNGHIDNFRLDMAANTLYEFIWNQFCDWYLELTKPVLW--KGTEAQQRATRRTLI 741
            A ++     +++        L  F   +   +YL++ K   +  K     +R+ +  L 
Sbjct: 694 AAQEDILKAYESYDFHEVVQRLMRFCSIEMGSFYLDIIKDRQYTAKADSVARRSCQTALF 753

Query: 742 TVLEKTLRLAHPVIPYITETIW 763
            + E  +R   P++ +  + IW
Sbjct: 754 HIAEALVRWMAPIMSFTADEIW 775