Pairwise Alignments

Query, 467 a.a., 3-isopropylmalate dehydratase large subunit from Vibrio cholerae E7946 ATCC 55056

Subject, 473 a.a., 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) from Variovorax sp. SCN45

 Score =  586 bits (1510), Expect = e-172
 Identities = 302/471 (64%), Positives = 355/471 (75%), Gaps = 7/471 (1%)

Query: 4   AKTLYEKIYDAHVVVAAPGETPILYIDRHLVHEVTSPQAFDGLREKGRPVRQVSKTFATM 63
           A+TLY+KI+D HVV      T ILYIDRHLVHEVTSPQAF+GLRE GR + ++S   AT 
Sbjct: 2   ARTLYDKIWDEHVVHTEEDGTAILYIDRHLVHEVTSPQAFEGLREAGRKLWRISSVVATA 61

Query: 64  DHNVSTTTKDINASG---EMARIQMQTLSKNCEEFGVT-LYDINHKYQGIVHVMGPELGI 119
           DHN  TT  +    G     ++ Q+ TL  N  EFG    +    K QGIVHV+GPE G 
Sbjct: 62  DHNTPTTGWERGYEGIADPTSKEQVTTLDHNIAEFGAAAFFPFLSKRQGIVHVIGPESGA 121

Query: 120 TLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEVRGKVAPG 179
           TLPGMT+VCGDSHT+THGAFG+LA GIGTSEVEHV+ATQTL   +AK M ++V GK+  G
Sbjct: 122 TLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVMATQTLLGKKAKNMLVKVDGKLPLG 181

Query: 180 ITAKDIVLAIIGKTTAAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIELGAKAGLIAPDA 239
            TAKDIVLAIIGK   AGGTGY +EF G AIRDLSMEGRMTVCNMAIE GA+AGL+A D 
Sbjct: 182 CTAKDIVLAIIGKIGTAGGTGYTIEFAGSAIRDLSMEGRMTVCNMAIEAGARAGLVAVDE 241

Query: 240 TTFNYIKGRKFAPQGSDWDAAVDYWQTLKTDEDAQFDAVVTLEASEIKPQVTWGTNPGQV 299
            T +Y+KGR  AP G +WD AV YW+TL++D  A+FDAVV L+A+ I PQVTWGT+P  V
Sbjct: 242 KTISYVKGRPLAPTGVEWDQAVSYWRTLQSDPGAKFDAVVELDAATIPPQVTWGTSPEMV 301

Query: 300 IAVDEPIPSPSQFADPVERSSAEKALAYMGLEAGKMLSDYKVDKVFVGSCTNSRIEDMRA 359
           + ++  +P P +  D  +R + E+AL YMGLE  K ++D  +DKVF+GSCTNSRIEDMR 
Sbjct: 302 VEINGRVPDPDKEKDANKRGAIERALVYMGLEPNKAMNDIFIDKVFIGSCTNSRIEDMRE 361

Query: 360 AAAVAK--GKKVASHVQ-ALIVPGSEQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMN 416
           AAAV K  G+KVA +V+ A++VPGS  VK QAE EGLD IF  AGFEWR PGCSMCLAMN
Sbjct: 362 AAAVVKKLGQKVAKNVKLAMVVPGSGVVKEQAEREGLDVIFKAAGFEWREPGCSMCLAMN 421

Query: 417 NDRLGPGERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRQF 467
            DRL PGERCASTSNRNFEGRQG  GRTHLVSPAMAAAAA+ GHFVD+R F
Sbjct: 422 ADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVHGHFVDVRTF 472