Pairwise Alignments

Query, 363 a.a., 3-isopropylmalate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 363 a.a., 3-isopropylmalate dehydrogenase (VIMSS) from Escherichia coli BW25113

 Score =  554 bits (1427), Expect = e-162
 Identities = 274/357 (76%), Positives = 308/357 (86%)

Query: 4   RDYKIAVLPGDGIGPEVMAQAHKVLDAIEQKHGIRFSREEHDVGGIAIDNHGCPLPESTL 63
           ++Y IAVLPGDGIGPEVM QA KVLDA+  +  +R +   +DVGG AIDNHG PLP +T+
Sbjct: 3   KNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATV 62

Query: 64  RACEEADAVLFGSVGGPKWEHLPPNEQPERGALLPLRKHFQLFCNLRPAQIHQGLEAFSP 123
             CE+ADAVLFGSVGGPKWEHLPP++QPERGALLPLRKHF+LF NLRPA+++QGLEAF P
Sbjct: 63  EGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCP 122

Query: 124 LRADISARGFDIVVVRELTGGIYFGQPKGREGEGAHEKAFDTEVYHRFEIERIARIAFES 183
           LRADI+A GFDI+ VRELTGGIYFGQPKGREG G +EKAFDTEVYHRFEIERIARIAFES
Sbjct: 123 LRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFES 182

Query: 184 ARLRRKKVCSIDKANVLQSSILWREVVSEIAKEYPDVSLSHMYIDNATMQLIKDPAQFDV 243
           AR RR KV SIDKANVLQSSILWRE+V+EIA EYPDV L+HMYIDNATMQLIKDP+QFDV
Sbjct: 183 ARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDV 242

Query: 244 MLCSNIFGDILSDECAMITGSMGMLPSASMNESKFGLYEPAGGSAPDIAGKNIANPVAQI 303
           +LCSN+FGDILSDECAMITGSMGMLPSAS+NE  FGLYEPAGGSAPDIAGKNIANP+AQI
Sbjct: 243 LLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQI 302

Query: 304 LSAALMLRYSLGEEAAARDIENAVSQALAAGELTADLAGSKPALSTSAMGDKIASYI 360
           LS AL+LRYSL  + AA  IE A+++AL  G  T DLA    A+ST  MGD IA Y+
Sbjct: 303 LSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYV 359