Pairwise Alignments

Query, 738 a.a., GTP diphosphokinase from Vibrio cholerae E7946 ATCC 55056

Subject, 707 a.a., bifunctional GTP diphosphokinase/guanosine-3' 5'-bis pyrophosphate 3'-pyrophosphohydrolase from Erwinia amylovora T8

 Score =  394 bits (1011), Expect = e-113
 Identities = 230/689 (33%), Positives = 366/689 (53%), Gaps = 55/689 (7%)

Query: 64  ILITLSMDRPTLVAALLFPIATSGVLDNESLEEGYGREVVKLIHGVEEMAAIGQLNVTMH 123
           IL  + +D  TL+AALL  +        + +E+ +G+ V +L+ GV +      L+    
Sbjct: 55  ILAEMKLDHETLMAALLHDVIEDTPATYQDMEQLFGQTVAELVEGVSK------LDKLKF 108

Query: 124 GSEASAQVDNVRRMLLAMVDDFRCVVIKLAERICNLREVKN-EPDEVRRVAAKECANIYA 182
             +  AQ +N R+M++AMV D R ++IKLA+R  N+R +    PD+ RR+A  E   IY+
Sbjct: 109 RDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGALRPDKKRRIAL-ETLEIYS 167

Query: 183 PLANRLGIGQLKWEIEDYAFRYQQPDTYKQIAKQLSERRIVREQYIRDFVSDLRAEMKQS 242
           PLA+RLGI  LK E+E+  F    P+ Y+ I + +   R  R++ I+  +S++   ++++
Sbjct: 168 PLAHRLGIHHLKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIDGRLEEA 227

Query: 243 GINAEVSGRPKHIYSIWRKMQKKSLAFDELFDVRAVRIIADKLQDCYAALGIVHTKYKHL 302
           GI   VSGR KH+YSI+ KM  K   F  + D+ A R+I   +  CY  LG +H  YK  
Sbjct: 228 GITRRVSGREKHLYSIYCKMHLKEQRFHSIMDIYAFRVIVRDVDTCYRVLGQMHNLYKPR 287

Query: 303 PNEFDDYVANPKPNGYQSIHTVILGPEGKTIEIQIRTKQMHEESELGVAAHWKYKEGSSA 362
           P    DY+A PK NGYQS+HT ++GP G  +E+QIRT+ M + +E+GVAAHW YKE   +
Sbjct: 288 PGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMGVAAHWAYKEQGES 347

Query: 363 ARSGYDEKITWLRKLLDWQEEMSDSGEMLDELRSQVFDDRVYAFTPKGDVVDLPMGATPL 422
             +       WL+ LL+ Q+    S E ++ ++S +F D +Y FTP+G +V+LP GATP+
Sbjct: 348 GTTAQIRAQRWLQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVELPAGATPV 407

Query: 423 DFAYHIHSEVGHRCIGAKVAGRIVPFTHKLQMGDQVEIITAKEPNPSRDWLNPSLGFVHS 482
           DFAY +H+++GH C+GA+V  +  P +  L  G  VEIITA    P+  WLN    FV S
Sbjct: 408 DFAYAVHTDIGHACVGARVDRQPYPLSQALTSGQTVEIITAPGARPNAAWLN----FVVS 463

Query: 483 GRARAKINAWFRKQSREKNLEAGREILEIELAKIGANLKHAE------AYALKRFNVNSV 536
            +ARAKI    +   R+ ++  GR +L   L   G + K AE       + L+R  + S+
Sbjct: 464 SKARAKIRQLLKNLKRDDSVSLGRRLLNHAL---GGSRKLAEIPPANVQHELERMKLASL 520

Query: 537 DEMYVGIGSGDLRINQIVNHINALVNKPTAEEEDKLALEKLQENKTLTPNRP-------- 588
           D++   IG G        N ++ +V K             LQ+N+   PN P        
Sbjct: 521 DDLLAEIGLG--------NAMSVVVAK------------NLQQNE---PNAPATGPASAG 557

Query: 589 -HKDAVVVEGVDNLMTHLARCCQPIPGDEIRGYITQGRGISVHRSDCEQLEELSLHAPER 647
             +  + ++G D ++   A+CC+PIPGD I  +++ G+G+ VH   C  +       PE+
Sbjct: 558 SSRSKLPIKGADGVLITFAKCCRPIPGDPIVAHVSPGKGLVVHHESCRNIRGYQ-KEPEK 616

Query: 648 IIDTVWGSGFVGSYLLTVRVEAMERSGLLKDITTLLANEKVKVASMKSRSDYKRQIIIMD 707
            +   W       ++  ++V+     G L ++T  +      + S+ +     R +    
Sbjct: 617 YMAVEWDKVTEQEFVAEIKVDMFNHQGALANLTAAINTAGSNIQSLNTEEKDGR-VYCAF 675

Query: 708 FDLEVNNVEALARVSKRIEQIKDVMLVKR 736
             L   +   LA + ++I  + DV+ V R
Sbjct: 676 IRLTARDRVHLANIMRKIRVMPDVIKVHR 704