Pairwise Alignments

Query, 886 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Vibrio cholerae E7946 ATCC 55056

Subject, 881 a.a., Pyruvate dehydrogenase E1 component from Pseudomonas putida KT2440

 Score = 1079 bits (2791), Expect = 0.0
 Identities = 536/882 (60%), Positives = 673/882 (76%), Gaps = 9/882 (1%)

Query: 7   DVDALETQEWLAALESVVREEGVERAQYLLEQVLEKARLDGVDMPTGVTTNYINTIPAAQ 66
           D+D +ETQEWL ALESV+ +EG +RA YL+ ++ E A   G  +P  +TT Y NTIP   
Sbjct: 3   DLDPIETQEWLDALESVLDKEGEDRAHYLMTRMGELATRSGSQLPYAITTPYRNTIPVTH 62

Query: 67  EPAYPGDTTIERRIRSIIRWNAIMIVLRASKKDLELGGHMASFQSSAAFYETCFNHFFRA 126
           E   PGD  +ERRIRS++RWNA+ +V+R + KD +LGGH++SF SSA  Y+  FN+FF+A
Sbjct: 63  EARMPGDLFMERRIRSMVRWNALAMVMRTNLKDSDLGGHISSFASSATLYDIGFNYFFQA 122

Query: 127 PNEKDGGDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPKLMPEFW 186
           P E+ GGDL+++QGH SPG+YARAF+EGR++E+Q++NFRQEVDG GL SYPHP LMP+FW
Sbjct: 123 PTEEHGGDLIFFQGHASPGVYARAFMEGRISEDQMNNFRQEVDGNGLSSYPHPWLMPDFW 182

Query: 187 QFPTVSMGLGPISAIYQARFLKYLNGRGLKDTTAQRVYAFLGDGEMDEPESRGAISFAAR 246
           QFPTVSMGLGPI AIYQARF+KYL  RG      Q+V+ F+GDGE DEPES GAI+ A R
Sbjct: 183 QFPTVSMGLGPIQAIYQARFMKYLEARGFIPAGKQKVWCFMGDGECDEPESLGAIALAGR 242

Query: 247 EKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKLLAKDTT 306
           EKLDNL F+INCNLQRLDGPV GNGKIIQELEG+FRG GWNV KV+WG  WD LLAKDT 
Sbjct: 243 EKLDNLIFVINCNLQRLDGPVRGNGKIIQELEGVFRGGGWNVNKVVWGRFWDPLLAKDTN 302

Query: 307 GKLLQLMNETIDGDYQTFKAKDGAYVREHFFGKYPETAALVADMTDDEIFALKRGGHESS 366
           G L + M+E IDG+YQ +KAKDGAYVREHFF   PE  A+V D++D+EI+ L RGGH+  
Sbjct: 303 GALQRRMDEVIDGEYQNYKAKDGAYVREHFFNT-PELKAMVEDLSDEEIWKLNRGGHDPY 361

Query: 367 KLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMRNRLGLQ 426
           K+YAA+  A + K +PTVILAKT+KGYG G A E KN AH  KK+D+  +   R+R  + 
Sbjct: 362 KVYAAYHQAVNHKEQPTVILAKTIKGYGTG-AGEAKNTAHNTKKVDVDSLRHFRDRFDIP 420

Query: 427 DLISDEEVKNLPYLKLEEGSKEFEYLHARRKALHGYTPQRLPNFTGEFIVPALEDFKPLL 486
             + D +++NLP+ K EEGS E +YL  RR AL G+ PQR    +     P LE  K +L
Sbjct: 421 --VKDADLENLPFFKPEEGSAEAKYLAERRAALGGFVPQRRAK-SFSVPTPPLETLKAIL 477

Query: 487 E-EQSREISSTMAYVRSLNILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYNPHGQN 545
           +    REIS+TMA+VR L  L+KDK+IGQ IVPII DEARTFGMEG+FRQ+GIY+  GQ 
Sbjct: 478 DGSGDREISTTMAFVRILAQLVKDKDIGQRIVPIIPDEARTFGMEGMFRQLGIYSSVGQL 537

Query: 546 YTPQDRDIVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYIYYSMFGF 605
           Y P D+D V +Y+E   GQ+L+EGINE GAMSS++AA TSYS +N PM+PFYI+YSMFGF
Sbjct: 538 YEPVDKDQVMFYREDKKGQILEEGINEAGAMSSFIAAGTSYSCHNQPMLPFYIFYSMFGF 597

Query: 606 QRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCISYDPTFAY 665
           QR+GD+AW AGD + RGFL+G TAGRTTLNGEGLQHEDGHSH++AGT+PNC +YDPT+ Y
Sbjct: 598 QRIGDLAWAAGDSRTRGFLIGGTAGRTTLNGEGLQHEDGHSHMMAGTIPNCRTYDPTYGY 657

Query: 666 EVAVILQDGIRRMYGEQENVFYYLTLMNESYAHPAMPAGAEEGIRKGIYKLETHAGNKA- 724
           E+AVI+QDG+++M  EQ+++FYY+T+MNESY  PAMPAG EEGI KG+Y LE      A 
Sbjct: 658 ELAVIIQDGMKKMTEEQQDIFYYITVMNESYQQPAMPAGVEEGIIKGMYLLEEDTREAAH 717

Query: 725 KVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNMLHPEAEVK 784
            VQLM SGTI+ EVR+AA+IL EE+ V +DV+SVTSFNEL RDG A +R N L P  + +
Sbjct: 718 HVQLMGSGTILREVREAAKILREEFNVGADVWSVTSFNELRRDGLAVERANRLKPGQKPQ 777

Query: 785 VPYIAQVMGTE--PAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSDSRENLRRHFE 842
             Y+ Q +     P IA+TDYMK +A+Q+R ++P++ +KVLGTDG+GRSDSR+ LR  FE
Sbjct: 778 QTYVEQCLNGRKGPVIASTDYMKLFAEQIRQWVPSKEFKVLGTDGYGRSDSRKKLRHFFE 837

Query: 843 VNAGYVVVAALNELAKRGEVEKSVVAAAIKKFDIDTEKTNPL 884
           V+  +VV+AAL  LA RGE+E  VVA AI KF ID +K NPL
Sbjct: 838 VDRHFVVLAALEALADRGEIEPKVVADAIVKFGIDPDKRNPL 879