Pairwise Alignments

Query, 886 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Vibrio cholerae E7946 ATCC 55056

Subject, 887 a.a., pyruvate dehydrogenase (acetyl-transferring), homodimeric type from Escherichia coli ECRC101

 Score = 1345 bits (3482), Expect = 0.0
 Identities = 647/883 (73%), Positives = 761/883 (86%), Gaps = 4/883 (0%)

Query: 6   HDVDALETQEWLAALESVVREEGVERAQYLLEQVLEKARLDGVDMPTGV-TTNYINTIPA 64
           +DVD +ET++WL A+ESV+REEGVERAQYL++Q+L +AR  GV++  G   +NYINTIP 
Sbjct: 7   NDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNYINTIPV 66

Query: 65  AQEPAYPGDTTIERRIRSIIRWNAIMIVLRASKKDLELGGHMASFQSSAAFYETCFNHFF 124
            ++P YPG+  +ERRIRS IRWNAIM VLRASKKDLELGGHMASFQSSA  Y+ CFNHFF
Sbjct: 67  EEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFF 126

Query: 125 RAPNEKDGGDLVYYQGHISPGIYARAFVEGRLTEEQLDNFRQEVDGKGLPSYPHPKLMPE 184
           RA NE+DGGDLVY+QGHISPG+YARAF+EGRLT+EQLDNFRQEV G GL SYPHPKLMPE
Sbjct: 127 RARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPHPKLMPE 186

Query: 185 FWQFPTVSMGLGPISAIYQARFLKYLNGRGLKDTTAQRVYAFLGDGEMDEPESRGAISFA 244
           FWQFPTVSMGLGPI AIYQA+FLKYL  RGLKDT+ Q VYAFLGDGEMDEPES+GAI+ A
Sbjct: 187 FWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESKGAITIA 246

Query: 245 AREKLDNLCFLINCNLQRLDGPVMGNGKIIQELEGLFRGAGWNVVKVIWGNGWDKLLAKD 304
            REKLDNL F+INCNLQRLDGPV GNGKII ELEG+F GAGWNV+KV+WG+ WD+LL KD
Sbjct: 247 TREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKD 306

Query: 305 TTGKLLQLMNETIDGDYQTFKAKDGAYVREHFFGKYPETAALVADMTDDEIFALKRGGHE 364
           T+GKL+QLMNET+DGDYQTFK+KDGAYVREHFFGKYPETAALVAD TD++I+AL RGGH+
Sbjct: 307 TSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHD 366

Query: 365 SSKLYAAFKNAQDTKGRPTVILAKTVKGYGMGDAAEGKNIAHQVKKMDMTHVLAMRNRLG 424
             K+YAAFK AQ+TKG+ TVILA T+KGYGMGDAAEGKNIAHQVKKM+M  V  +R+R  
Sbjct: 367 PKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFN 426

Query: 425 LQDLISDEEVKNLPYLKLEEGSKEFEYLHARRKALHGYTPQRLPNFTGEFIVPALEDFKP 484
           +   +SD +++ LPY+   EGS+E  YLHA+R+ LHGY P R PNFT +  +P+L+DF  
Sbjct: 427 VP--VSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGA 484

Query: 485 LLEEQSREISSTMAYVRSLNILLKDKNIGQNIVPIIADEARTFGMEGLFRQIGIYNPHGQ 544
           LLEEQS+EIS+T+A+VR+LN++LK+K+I   +VPIIADEARTFGMEGLFRQIGIY+P+GQ
Sbjct: 485 LLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQ 544

Query: 545 NYTPQDRDIVSYYKEATSGQVLQEGINELGAMSSWVAAATSYSTNNLPMIPFYIYYSMFG 604
            YTPQDR+ V+YYKE   GQ+LQEGINELGA  SW+AAATSYSTNNLPMIPFYIYYSMFG
Sbjct: 545 QYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFG 604

Query: 605 FQRVGDMAWMAGDQQARGFLLGATAGRTTLNGEGLQHEDGHSHILAGTVPNCISYDPTFA 664
           FQR+GD+ W AGDQQARGFL+G T+GRTTLNGEGLQHEDGHSHI + T+PNCISYDP +A
Sbjct: 605 FQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYA 664

Query: 665 YEVAVILQDGIRRMYGE-QENVFYYLTLMNESYAHPAMPAGAEEGIRKGIYKLETHAGNK 723
           YEVAVI+ DG+ RMYGE QENV+YY+T +NE+Y  PAMP GAEEGIRKGIYKLET  G+K
Sbjct: 665 YEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSK 724

Query: 724 AKVQLMSSGTIMNEVRKAAQILSEEYGVASDVYSVTSFNELARDGQACDRFNMLHPEAEV 783
            KVQL+ SG+I+  VR+AA+IL+++YGV SDVYSVTSF ELARDGQ C+R+NMLHP    
Sbjct: 725 GKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETP 784

Query: 784 KVPYIAQVMGTEPAIAATDYMKNYADQVRAFIPAQSYKVLGTDGFGRSDSRENLRRHFEV 843
           +VPYIAQVM   PA+A+TDYMK +A+QVR ++PA  Y+VLGTDGFGRSDSRENLR HFEV
Sbjct: 785 RVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEV 844

Query: 844 NAGYVVVAALNELAKRGEVEKSVVAAAIKKFDIDTEKTNPLYA 886
           +A YVVVAAL ELAKRGE++K VVA AI KF+ID +K NP  A
Sbjct: 845 DASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNPRLA 887