Pairwise Alignments

Query, 635 a.a., pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase from Vibrio cholerae E7946 ATCC 55056

Subject, 423 a.a., Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex from Pseudomonas putida KT2440

 Score =  198 bits (504), Expect = 3e-55
 Identities = 137/431 (31%), Positives = 219/431 (50%), Gaps = 51/431 (11%)

Query: 212 VQVPDIGGD--EVTVTEIMVNVGDSISEEQSLITVEGDKASMEVPAPFAGTLKEIKVATG 269
           +++PDIG    +V + E  V VGD I+E+Q +  V  DKA++E+P+P +G +  +    G
Sbjct: 6   IKMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPG 65

Query: 270 DKVKTGSLIMVFEVAGAA-----PVAAPVQAAAAPAAA---PAQAATPAA-AAPATSGEF 320
           + +  GS ++  EV G+      P   PV+A AAP AA   P +   PA   APA     
Sbjct: 66  EVMAVGSELIRIEVEGSGNHVDVPQPKPVEAPAAPIAAKPEPQKDVKPAVYQAPA----- 120

Query: 321 QENHEYSH-----------ASPVVRRLAREFGVNLAKVKGSGRKNRILKEDVQNYVKEAL 369
             NHE +            ASP VR+ A + G+ L  V GSG   RIL ED+  ++ +  
Sbjct: 121 --NHEAAPIVPRQPGDKPLASPAVRKRALDAGIELRYVHGSGPAGRILHEDLDAFMSKP- 177

Query: 370 KRLESGAQAAASGKGDGAALGLLPWPKVDFSKFGDTEVQPLSRIKKISGANLHRNWVMIP 429
              +S A  A  G                ++K  D+E  P+  +++     +      + 
Sbjct: 178 ---QSNAGQAPDG----------------YAKRTDSEQVPVIGLRRKIAQRMQDAKRRVA 218

Query: 430 HVTQWDNADITELEKFRQEQNAMEAKRDTGMKITPLVFIMKAAAKALEAFPAFNSSLSDD 489
           H +  +  D+T LE  RQ+ N+     D+  K+T L F+++A   AL  FP  N++  D+
Sbjct: 219 HFSYVEEIDVTALEALRQQLNSKHG--DSRGKLTLLPFLVRALVVALRDFPQINATYDDE 276

Query: 490 GESLILKKYVNIGIAVDTPNGLVVPVFKDVNKKGIYELSKELAEVSKKARGGKLTAADMQ 549
            + +     V++GIA    NGL+VPV +      ++  + E++ ++  AR  K +  ++ 
Sbjct: 277 AQIITRHGAVHVGIATQGDNGLMVPVLRHAEAGSLWANAGEISRLANAARNNKASREELS 336

Query: 550 GGCFTISSLGGIGGTAFTPIVNAPEVAILGVSKSEMKPVWNGKEFAPRLQLPLSLSYDHR 609
           G   T++SLG +GG   TP+VN PEVAI+GV++   +PV    +   R  + LS S+DHR
Sbjct: 337 GSTITLTSLGALGGIVSTPVVNTPEVAIVGVNRMVERPVVIDGQIVVRKMMNLSSSFDHR 396

Query: 610 VIDGAEGARFI 620
           V+DG + A FI
Sbjct: 397 VVDGMDAALFI 407



 Score = 65.5 bits (158), Expect = 5e-15
 Identities = 38/100 (38%), Positives = 60/100 (60%), Gaps = 7/100 (7%)

Query: 112 VQVPDIGGD--EVEVTEIMVKVGDVVAEEQSLITVEGDKASMEVPAPFAGTVKEIKIAAG 169
           +++PDIG    +VE+ E  VKVGD++AE+Q +  V  DKA++E+P+P +G V  +    G
Sbjct: 6   IKMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPG 65

Query: 170 DKVSTGSLIMVFEVAGA-----APLAAPVQAAAPAAAAAP 204
           + ++ GS ++  EV G+      P   PV+A A   AA P
Sbjct: 66  EVMAVGSELIRIEVEGSGNHVDVPQPKPVEAPAAPIAAKP 105



 Score = 62.0 bits (149), Expect = 5e-14
 Identities = 38/100 (38%), Positives = 57/100 (57%), Gaps = 6/100 (6%)

Query: 11  IYVPDIGAD--EVEVTEILVKVGDKVAEEQSLITVEGDKASMEVPASQAGIVKEIKVVAG 68
           I +PDIG    +VE+ E  VKVGD +AE+Q +  V  DKA++E+P+  +G V  +    G
Sbjct: 6   IKMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPG 65

Query: 69  DKVSTGSLIMVFEAEGAA----AAAPAPAPQAAAPVAAAP 104
           + ++ GS ++  E EG+        P P    AAP+AA P
Sbjct: 66  EVMAVGSELIRIEVEGSGNHVDVPQPKPVEAPAAPIAAKP 105