Pairwise Alignments

Query, 444 a.a., UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase from Vibrio cholerae E7946 ATCC 55056

Subject, 706 a.a., UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase (EC 6.3.2.9) from Variovorax sp. SCN45

 Score =  189 bits (479), Expect = 3e-52
 Identities = 139/416 (33%), Positives = 198/416 (47%), Gaps = 49/416 (11%)

Query: 73  ADLVVTNPGIALATPEIQQVLAAGIPVVGDIELFAWHVDTP-VIAITGSNGKSTVTDLSG 131
           A+L  TNP  A    E  Q     + +   +E  A    TP V+AITG+NGK+TVT L+G
Sbjct: 280 AELSATNPASAAVEEESPQ-----LELAPPVEPEAPKGYTPSVLAITGTNGKTTVTSLTG 334

Query: 132 VLANAAGVKAAVGGNIGVPALDLISPDVE------LYVLELSSFQLETTSSLKLKAAAFL 185
            L    G   AV GNIG   LD +   ++      ++VLELSSFQL+     +  AA  L
Sbjct: 335 QLVERGGKTVAVAGNIGPTLLDTLWAHIDADTLPDVWVLELSSFQLDGVQDFEPTAATVL 394

Query: 186 NLSEDHMDRYQGMEDYRQAKLRIFDHAETAVVNADDTQTFPDHAAHLQV----------V 235
           NL++DH+D +  M  Y  AK RIF      ++N DD        A ++V          V
Sbjct: 395 NLTQDHLDWHGDMSAYAAAKARIFGARGLMILNRDDAGVMAMLPAPVKVKLQRPQIRTHV 454

Query: 236 TFGVE---QAAQFSLAQHQGREYLFARDEA--------------------VMACAELSLV 272
           TFG     +   + + +  G  +L    EA                    +M    L + 
Sbjct: 455 TFGAAMPLRPGDYGIERVNGMAWLVRALEADETQKRKRGAVVEEEIFLQRLMPADALRIR 514

Query: 273 GRHNVANVLTVLALLDSAGVNFRLALDALKSYTGLTHRCQVVADNHGIKWVNDSKATNVA 332
           GRHN  N L  LAL  +AG      L  L+ Y G  HR + +A    +++ +DSK TNV 
Sbjct: 515 GRHNAMNALAALALASAAGCPLGPMLYGLREYHGEPHRVEPIAIVDEVEYFDDSKGTNVG 574

Query: 333 STLAALSGLKIEGQLYLLVGGVGKGADFTPLAPVLATLPVQLCCFGVDGH----QFMPLH 388
           +T+AAL+GL  E ++ +++GG GKG DF PLA  +      +   G D            
Sbjct: 575 ATVAALAGLGEERRVVVILGGEGKGQDFEPLAAPVRQYARAVVLIGRDASIIEAALASTG 634

Query: 389 PSARFYDSMESIIRSIRPQLKSGDMVLLSPACASFDQFKNFMARGDIFAQLARQYA 444
            S     SME  +++   +   GD VLLSPACASFD F+++  R D+F +  + +A
Sbjct: 635 VSLMHAGSMEEAVQAAAARANPGDAVLLSPACASFDMFRDYEHRADVFREAVQSWA 690



 Score = 45.1 bits (105), Expect = 7e-09
 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 9/102 (8%)

Query: 13  HVVVVGLGITGLSVVNYLRKYHPSVTVQVIDTREAPPGQEQLSS---DVALHRSGWNLEW 69
           HV+++GLG +GL++  +  ++   VT  V DTREAP     L +   +VA     +    
Sbjct: 8   HVLILGLGASGLAMARWCARHGAVVT--VADTREAPASLATLKAEWPEVAFVGGPFTAAL 65

Query: 70  LLNADL--VVTNPGIALAT--PEIQQVLAAGIPVVGDIELFA 107
           +    +  V  +PG++ AT  P      A G+PV G+++LFA
Sbjct: 66  VEGTPIRAVYRSPGLSPATIAPVADAARAMGLPVGGELDLFA 107