Pairwise Alignments

Query, 1487 a.a., glutamate synthase large subunit from Vibrio cholerae E7946 ATCC 55056

Subject, 1585 a.a., Glutamate synthase [NADPH] large chain (EC 1.4.1.13) from Variovorax sp. SCN45

 Score = 1174 bits (3036), Expect = 0.0
 Identities = 657/1514 (43%), Positives = 913/1514 (60%), Gaps = 75/1514 (4%)

Query: 3    LYDPSLEKDNCGFGLIAHMEGQASHKLVRTAISALDRMTHRGGIAADGKTGDGCGLLLQK 62
            LY  + E D CG G +AH++G+ SH +V   +  L+ + HRG + AD   GDG G+L+Q 
Sbjct: 15   LYSGADEHDACGVGFVAHIKGEKSHAIVLQGLKILENLDHRGAVGADKLMGDGAGILIQL 74

Query: 63   PDSYLRLIAEEQHWKLSK--QYAIGMLFLSRDPHKAQLAQQIVNQELAKETLSVAGWRKV 120
            PD   R    +Q   L    +Y +GM+FL ++    +  +Q + + +  E   + GWR V
Sbjct: 75   PDHLYREEMAKQGVTLPPPGEYGVGMIFLPKEHASREACEQEMERAIKAEGQVLLGWRDV 134

Query: 121  PTNPKV-LGPIALDSLPDIQQVFISAPAGWRERD-VERRLYIARRRIEKQIT-----DDR 173
            P N  + + P   +  P ++QVFI        +D +ER+LY+ R+     I        +
Sbjct: 135  PVNRDMPMSPTVREKEPLLRQVFIGRGNDVIVQDALERKLYVIRKTASANIQRLKLKHSK 194

Query: 174  DFYICSLSTQVLVYKGLCMPADLPRFYLDLADLRMESAICLFHQRFSTNTQPRWPLAQPF 233
            ++Y+ S+S++ +VYKGL +   +  +YLDL D R  SA+ L HQRFSTNT P WPLA P+
Sbjct: 195  EYYVPSMSSRTVVYKGLLLADQVGTYYLDLQDKRCVSALGLVHQRFSTNTFPEWPLAHPY 254

Query: 234  RYLAHNGEINTIEGNRQWARARAYKFASPLL-PDLQSAAPFVNETGSDSSSLDNMLDLFL 292
            RY+AHNGEINT++GN  W +AR    +SP+L  DLQ   P      SD+++ DN L+L  
Sbjct: 255  RYVAHNGEINTVKGNYNWMKAREGVMSSPVLGADLQKLYPISFAGQSDTATFDNCLELLT 314

Query: 293  AGGMDIFRAMRMLVPPAWQNHPDMDPDLRAFYDFNSKHMEPWDGPAGIVLSDGRYAACNL 352
              G  I +A+ M++P  W+ H  MD   RAFY++++  +EPWDGPA IV +DGR     L
Sbjct: 315  MAGYPISQAVMMMIPEPWEQHATMDTRRRAFYEYHAAMLEPWDGPASIVFTDGRQIGATL 374

Query: 353  DRNGLRPARYVITKDKLITLASEVGIWDYAPDEVSEKGRVGPGELLVIDTRKGKIWQSSE 412
            DRNGLRP+RY +T D L+ +ASE G+      ++  K R+ PG++ +ID  +G++    E
Sbjct: 375  DRNGLRPSRYCVTDDDLVIMASESGVLPVPEQKIVRKWRLQPGKMFLIDLEQGRMIDDEE 434

Query: 413  IDNDLKSRHPYREWMENNVHKLTPFSQLPDDKVGERSFDADL----LKTYQKQFAMSNEE 468
            + ++L +  PY++W+EN   KL        D V      A L    L   Q+ F  + E+
Sbjct: 435  VKSNLANSKPYKQWIENLRIKL--------DSVKAEPVSAPLSQVALLDRQQAFGYTQED 486

Query: 469  IDQILRVLGDMAQEAVGSMGDDTPMAVLSSKERLISDYFRQKFAQVTNPPIDPLREKHVM 528
            I  ++  +    +E +GSMG+D+P+AVLSSK + + +YF+Q FAQVTNPPIDP+RE  VM
Sbjct: 487  IKFLMSPMAQAGEEGIGSMGNDSPLAVLSSKNKPLYNYFKQLFAQVTNPPIDPIREAIVM 546

Query: 529  SLATSIGQEMNVF-CETDGHAHRVTFDSPILLYSDMQQLLTL---SDQHYRNTILDINFD 584
            SL + IG + N+          R+    PIL ++DM +L  +   +   +++ +LDI + 
Sbjct: 547  SLVSFIGPKPNLLDINQVNPPMRLEVSQPILDFADMAKLRDIGKYTQGKFKSYVLDITYP 606

Query: 585  PQ--EKNLKQAVLDLCDKAEQVVREGTVLVVLSDRALTADRLPIPAAMAVGAVQARLVEA 642
                ++ ++  +  LC +A   ++ G  ++++SDR ++  ++ IPA +A+ AV   LV  
Sbjct: 607  LAWGDEGVEAKLASLCAEAVDAIKGGHNILIISDRGVSPTQVAIPAVLALSAVHQYLVRE 666

Query: 643  NLRCDANIIIETGAARDPHHFAVLIGFGATAVYPYLAYETLGKMIDDGALQKSYREVMQN 702
             LR  A +++ETG+AR+ HHF VL G+GA AV+PYLA ETL  M  D     S  + + N
Sbjct: 667  GLRTTAGLVVETGSAREVHHFGVLAGYGAEAVHPYLAMETLTAMHADLPGDLSADKAVYN 726

Query: 703  YQYGINKGLYKIMSKMGISTVASYRCSQLFEAVGLHRDVVDLCFKGVTTRIQGANFDDFE 762
            Y   I KGL KIMSKMG+ST  SY  +QLFEA+GL+ + V+  F G  +R++G    +  
Sbjct: 727  YVKAIGKGLSKIMSKMGVSTYMSYCGAQLFEAIGLNSETVNKYFTGTASRVEGIGVFEIA 786

Query: 763  QDLFNLSRKAWAK----RKPLEHGGLLKYVHGGEYHAYNPDVVGTLQKAVKSGEIMDYRE 818
            ++   + + A+         L+ GG   +   GE H + PD +  LQ + ++     Y+E
Sbjct: 787  EEAIRMHKAAFGDDPVLANMLDAGGEYAWRTRGEEHMWTPDAIAKLQHSTRANNWNTYKE 846

Query: 819  FAQQVN--QRPVAMLRDLLRLKTSD-KPLPLEHIEPASDLYKRFDSAAMSIGALSPEAHE 875
            +AQ +N   R    LR L   K    K +P++ +E AS++ KRF + AMS+G++S EAH 
Sbjct: 847  YAQLINDQNRRHLTLRGLFEFKIDPAKAIPVDEVEAASEIVKRFATGAMSLGSISTEAHS 906

Query: 876  ALATAMNRLGGYSNSGEGGEDPRRF--------------------------------GTE 903
             LA AMNR+GG SN+GEGGEDP R+                                G  
Sbjct: 907  VLAVAMNRIGGKSNTGEGGEDPARYRNELKGIPIKQGDTLKSVIGAANVEVDMPLRDGDS 966

Query: 904  RNSRIKQVASGRFGVTPHYLTNADVLQIKVAQGAKPGEGGQLPGHKVTAEIAKLRYSVPG 963
              SRIKQVASGRFGVT  YL +AD +QIK+AQGAKPGEGGQLPG KVT  I K RY+VPG
Sbjct: 967  LRSRIKQVASGRFGVTAEYLHSADQIQIKMAQGAKPGEGGQLPGGKVTEYIGKQRYAVPG 1026

Query: 964  VTLISPPPHHDIYSIEDLAQLIFDLKQINPKALVSVKLVSEPGVGTIATGVAKAYADLIT 1023
            V LISPPPHHDIYSIEDLAQLI DLK   P A +SVKLVSE GVGTIA GVAK  +D + 
Sbjct: 1027 VGLISPPPHHDIYSIEDLAQLIHDLKNTAPHASISVKLVSEIGVGTIAAGVAKCKSDHVV 1086

Query: 1024 ISGYDGGTAASPLTSVKYAGSPWELGLAETQQALVANGLRHKIRLQVDGGLKTGLDVIKG 1083
            I+G+DGGT ASP +S+K+AGSPWE+GLAETQQ LV N LR +IR+Q DG +KTG DV  G
Sbjct: 1087 IAGHDGGTGASPWSSIKHAGSPWEIGLAETQQTLVLNRLRSRIRVQADGQMKTGRDVAIG 1146

Query: 1084 AILGAESFGFGTAPMVAMGCKFLRICHLNNCATGVATQDETLRKDYFKGLPEMVMNYFKG 1143
            A+LGA+ FGF TAP+V  GC  +R CHLN C  GVATQD  LRK  F G PE V+NYF  
Sbjct: 1147 ALLGADEFGFATAPLVVEGCIMMRKCHLNTCPVGVATQDPILRKK-FSGKPEHVVNYFFF 1205

Query: 1144 LAEEVRGYLAELGVEKLTDLIGRTDLLEVVEGMTA-KQSKLDLSDLLEAPVSPQNLPLYC 1202
            +AEEVR  +A+LG+ K  DLIGR DLL++ +G+   K S LD S L   P  P ++  + 
Sbjct: 1206 VAEEVRQIMAQLGIRKFDDLIGRADLLDMRKGIEHWKASGLDFSRLFALPNVPADVARFH 1265

Query: 1203 TEPNTPFDKGALNQKIVEDALAAVENQQSLELYYNVINTDRSIGARLSGEIAKRYGNLGV 1262
             E        AL+ K++E +  A++  + ++      N +RS+GA LSG + K +   G+
Sbjct: 1266 VENQDHGLDKALDVKLIEKSRPAIDKGEKVQFIEVARNVNRSVGAMLSGALTKVHPQ-GL 1324

Query: 1263 ATSPIKVVLNGTAGQSFGVWNAGGLELYLTGDANDYVGKGMAGGKIVIRPHQGTAFVCNE 1322
                I++ L GT GQSFG + A G+ LYL GDANDY GKG++GG++V+RP          
Sbjct: 1325 PDDSIRIQLEGTGGQSFGAFLARGITLYLIGDANDYTGKGLSGGRVVVRPSLDFRGEAVR 1384

Query: 1323 ATIIGNTCLYGATGGKLFAAGKAGERFAVRNSGTIAVIEGAGDNACEYMTGGIVAILGAT 1382
             TI+GNT LYGAT G+ +  G AGERFAVR SG  AVIEG GD+ CEYMTGG VA+LG T
Sbjct: 1385 NTIVGNTALYGATTGEAYLCGVAGERFAVRLSGATAVIEGTGDHGCEYMTGGTVAVLGKT 1444

Query: 1383 GVNFGAGMTGGFAYVLDENGDFQGRVNDESVEAVALTDLYIHQEHLRGLIAE--HLEETG 1440
            G NF AGM+GG A+V DE+G F  R N   +  V+L  +    E    +  +  H  ET 
Sbjct: 1445 GRNFAAGMSGGVAFVYDEDGQFASRCN---LAMVSLDKVLTSAEQTASVHRKIWHGGETD 1501

Query: 1441 SAHAERILANFDEW 1454
             A  +++L +   W
Sbjct: 1502 EAQLKKLLEDHHRW 1515