Pairwise Alignments

Query, 819 a.a., bifunctional aspartate kinase/homoserine dehydrogenase I from Vibrio cholerae E7946 ATCC 55056

Subject, 820 a.a., Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) from Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

 Score = 1025 bits (2650), Expect = 0.0
 Identities = 512/820 (62%), Positives = 640/820 (78%), Gaps = 1/820 (0%)

Query: 1   MRVLKFGGSSLADPERFLRAADIIANNAQQEEVAVVLSAPGKTTNKLVAVIESALRQGEV 60
           MRVLKFGG+S+A+ ERFLR ADI+ +NA+Q +VA VLSAP K TN LVA+IE  +   + 
Sbjct: 1   MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA 60

Query: 61  EAQIVELESSFYALLDGIKAQLPNLDDSAYQQQVHSSMTQLRQFVHGITLLGMCPDNVNA 120
              I + E  F  LL G+ +  P    +  +  V     Q++  +HGI+LLG CPD++NA
Sbjct: 61  LPNISDAERIFSDLLAGLASAQPGFPLARLKMVVEQEFAQIKHVLHGISLLGQCPDSINA 120

Query: 121 RIISKGERVSIQLMKAVMEAKGLPANLVDPVKYLLAKGDHLEAMVDVEISTQRFRQAPLP 180
            +I +GE++SI +M  ++EA+G    ++DPV+ LLA G +LE+ VD+  ST+R   + +P
Sbjct: 121 ALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASQIP 180

Query: 181 QQHVNIMPGFTAGNAQGELVCLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYNCDPRLV 240
             H+ +M GFTAGN +GELV LGRNGSDYSAAVLAACLRADCCEIWTDVDGVY CDPR V
Sbjct: 181 ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV 240

Query: 241 DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFQIPCLIKNSFNPQGAGTLIGQDTG 300
            DARLLKS+SYQEAMELSYFGA VLHP+TI PIAQFQIPCLIKN+ NPQ  GTLIG  + 
Sbjct: 241 PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASSD 300

Query: 301 EDKLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSAADVSIVLITQSSSEYSISF 360
           +D L +KGI+ L+N+ M +VSGPGMKGM+GMA+RVF AMS A +S+VLITQSSSEYSISF
Sbjct: 301 DDNLPVKGISNLNNMAMFSVSGPGMKGMIGMAARVFAAMSRAGISVVLITQSSSEYSISF 360

Query: 361 CIEAQHKALAQQALADAFELELKDGLLEPVEFVDNVAIITLVGDGMRTSRGVASQFFSSL 420
           C+     A A++A+ D F LELK+GLLEP+   + +AII++VGDGMRT RG++++FF++L
Sbjct: 361 CVPQSDCARARRAMQDEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL 420

Query: 421 AEVHVNVIAIAQGSSERAISAVIPDDKISEAIKACHENLFNSKHFLDVFVVGVGGVGGEL 480
           A  ++N++AIAQGSSER+IS V+ +D  +  ++  H+ LFN+   ++VFV+GVGGVGG L
Sbjct: 421 ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL 480

Query: 481 VDQIQRQQAKLAEKGIMMRVCGLANSKGMLLDSQGLPLEQWRDRMINADQAFSLENLVAL 540
           ++Q++RQQ  L  K I +RVCG+ANSK +L +  GL L+ W+  +  A+  F+L  L+ L
Sbjct: 481 LEQLKRQQTWLKNKHIDLRVCGVANSKALLTNVHGLNLDNWQAELAQANAPFNLGRLIRL 540

Query: 541 VQRNHIINPVLVDCTSSDEIANQYADFLAAGFHVVTPNKKANTASMSYYHQLRNVARHSR 600
           V+  H++NPV+VDCTSS  +A+QYADFL  GFHVVTPNKKANT+SM YYHQLR  A  SR
Sbjct: 541 VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRFAAAQSR 600

Query: 601 RKLMYETTVGAGLPVIENLQNLIAAGDELEKFSGILSGSLSFIFGKLDEGMTLSQATQLA 660
           RK +Y+T VGAGLPVIENLQNL+ AGDEL+KFSGILSGSLSFIFGKL+EGM+LSQAT LA
Sbjct: 601 RKFLYDTNVGAGLPVIENLQNLLNAGDELQKFSGILSGSLSFIFGKLEEGMSLSQATALA 660

Query: 661 KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELSDVDVEQALPAGFDASGSVEEFMA 720
           +E G+TEPDPRDDLSGMDVARKLLILARE G ELELSD+ +E  LP  FDASG V  FMA
Sbjct: 661 REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPNEFDASGDVTAFMA 720

Query: 721 RLAQADAAFAERVAQAKAEGKVLRYVAQI-VDGQCQVRIVAVDENDPMFKVKEGENALAF 779
            L Q D AFA RVA+A+ EGKVLRYV  I  DG C+V+I  VD NDP+FKVK GENALAF
Sbjct: 721 HLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLFKVKNGENALAF 780

Query: 780 YSRYYQPIPLVLRGYGAGSEVTAAGVFSDVMRTLGWKLGV 819
           YS YYQP+PLVLRGYGAG++VTAAGVF+D++RTL WKLGV
Sbjct: 781 YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV 820