Pairwise Alignments

Query, 936 a.a., 2-oxoglutarate dehydrogenase subunit E1 from Vibrio cholerae E7946 ATCC 55056

Subject, 943 a.a., 2-oxoglutarate dehydrogenase from Pseudomonas simiae WCS417

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 572/943 (60%), Positives = 712/943 (75%), Gaps = 8/943 (0%)

Query: 1   MHNGVMKAWLESSHLAGANATYVEDLYELYLSDPDLVSEEWKRVFDGLPAHPTNVVEQPH 60
           M   VM+    S +L+G NA YVE+LYELYL DP+ V EEW+  F  L +      +  H
Sbjct: 1   MQESVMQRMWNSGYLSGGNAAYVEELYELYLHDPNAVPEEWRTKFQTLSSDGNAATDVSH 60

Query: 61  SRVRDYFRRLAQETKH---YNVQVSDPEVDAKQVKVLQLINAYRFRGHEAAKLDPLGLWN 117
           + +RD F  LA+  +     +      E + KQV+VL+LI AYR RGH+AA+LDPLGLW 
Sbjct: 61  ATIRDQFVLLAKNQRRAQPVSAGSVSSEHEKKQVEVLRLIQAYRMRGHQAAQLDPLGLWK 120

Query: 118 RPEVAELNPSFHNLTQEDMEETFNVGSFAIGKDTMKLKDIYQSLQKIYCGSVGAEYMHIT 177
           RP  A+L+ + + LT  D++ TF  G   IGK+   L++I+++LQ+ YC ++GAE+ HIT
Sbjct: 121 RPAPADLSINHYGLTNADLDTTFRAGDLFIGKEEASLREIHEALQQTYCRTIGAEFTHIT 180

Query: 178 DTEQKRWIQQRLEPVVGTPVFSKEEKRTFLEELTAAEGLERYLGAKFPGAKRFSLEGGDA 237
           D+EQ+ W Q RLE V G PV S + +   LE +TAAEGLE+YLG K+PG KRF LEGG++
Sbjct: 181 DSEQRHWFQHRLEGVRGRPVLSADVRSHLLERVTAAEGLEKYLGTKYPGTKRFGLEGGES 240

Query: 238 LVPMTKEMIRHAGASGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGEGWGTGD 297
           L+PM  E+I+ +G+ G +E+VIGMAHRGRLN+LVN  GK P++LFDEF GK     G+GD
Sbjct: 241 LIPMLDELIQRSGSYGTKEIVIGMAHRGRLNVLVNTFGKNPRELFDEFEGKKKVELGSGD 300

Query: 298 VKYHQGFSADFATPGGDVHLALAFNPSHLEIVNPVVMGSVRARQDRLGDEDGSKVLPITI 357
           VKYHQGFS++  T GG+VHLA+AFNPSHLEIV+PVV GSVRARQDR  D  G KVLPI+I
Sbjct: 301 VKYHQGFSSNVMTTGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRNDTTGEKVLPISI 360

Query: 358 HGDSAIAGQGVVAETFNMSQARGFCVGGTVRIVVNNQVGFTTSNPRDTRSTMYCTDIAKM 417
           HGD+A AGQGVV ETF MSQ RGF  GGTV IV+NNQVGFT SNP D RST Y TD+AKM
Sbjct: 361 HGDAAFAGQGVVLETFQMSQTRGFKTGGTVHIVINNQVGFTISNPLDARSTEYATDVAKM 420

Query: 418 VQAPIFHVNSDDPEAVAFVTRLALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPLMY 477
           +QAPI HVN DDPEAV FVT+LA+DYR +FKRDVVIDLVCYRR GHNEADEP+ TQPLMY
Sbjct: 421 IQAPILHVNGDDPEAVLFVTQLAIDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMY 480

Query: 478 QKIKKHPTPRKLYADVLTERGECDLETATQLVNEYRDALDHGEVVVKEW--RPMAMHSVD 535
           Q+I K  T R+LYA+ LT+ G  D       V+EYR+ALD+G  VVK     P     VD
Sbjct: 481 QQITKQRTTRELYAESLTKAGVVDDARVQAKVDEYRNALDNGLHVVKSLVKEPNKELFVD 540

Query: 536 WSPYLGHDWHIPWNSEYAMERLQDLGRRVCQYPESHVLHSRVEKIYQDRLSMISGEKMLD 595
           W PYLGH W    ++ + ++ LQ+L  ++ + PE  V+  +V KIY+DR  M +G   ++
Sbjct: 541 WRPYLGHAWTARHDTSFDLKTLQELSAKLLEIPEGFVVQRQVAKIYEDRQKMQAGGLPIN 600

Query: 596 WGMAETLAYATLLDDGKRIRISGQDSGRGTFFHRHAVLHNQNDASTYIPLSQIHAGQGPF 655
           WG AET+AYATL  +G  IR++GQD GRGTF HRHAVLHNQ DA TYIPL  ++ GQ  F
Sbjct: 601 WGYAETMAYATLAFEGHPIRMTGQDIGRGTFSHRHAVLHNQKDAGTYIPLQNLYEGQPRF 660

Query: 656 EVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFANGAQVVIDQFISSGEQKWGRLC 715
           +++DS LSEEAVLAFEYGY+T  P+ L +WEAQFGDFANGAQVVIDQFI+SGE KWGRLC
Sbjct: 661 DLYDSFLSEEAVLAFEYGYSTTTPNALVIWEAQFGDFANGAQVVIDQFITSGEHKWGRLC 720

Query: 716 GLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVVVPSTPAQVYHMIRRQVVRPMRRP 775
           GLTMLLPHGYEGQGPEHSSARLERYLQLCAE N+QV VP+TPAQ+YH++RRQV+RP+R+P
Sbjct: 721 GLTMLLPHGYEGQGPEHSSARLERYLQLCAEHNIQVCVPTTPAQIYHLLRRQVIRPLRKP 780

Query: 776 LVVMSPKSLLRHPLCVSSMEDLAHGTFQPAIGEIDALNPSQVKRVVFCSGKVYYDLLEQR 835
           LVV++PKSLLRH L +S++EDLA G+FQ  I EIDAL+ ++V R+V CSGKVYYDLLE+R
Sbjct: 781 LVVLTPKSLLRHKLAISTLEDLADGSFQTVIPEIDALDAAKVTRLVLCSGKVYYDLLEKR 840

Query: 836 RANEQQDVAIVRIEQLYPFPLEEVQAAIANYTNVVDYVWCQEEPQNQGAWYSSQHNFRAA 895
           RA  ++D+AIVRIEQLYPFP +++  AIA YTN+ + VWCQEEP NQGAWYSSQH+ R +
Sbjct: 841 RAEGREDIAIVRIEQLYPFPEDDLMEAIAPYTNLTNVVWCQEEPMNQGAWYSSQHHLRRS 900

Query: 896 I---PAGADLKYAGRPASASPAVGYMSVHMKQQKALIEDALTL 935
           I        L+YAGR ASA+PA GY S+H +QQ+ L++DA T+
Sbjct: 901 IGNHNKALGLEYAGRDASAAPACGYASMHAEQQEKLLQDAFTV 943