Pairwise Alignments

Query, 936 a.a., 2-oxoglutarate dehydrogenase subunit E1 from Vibrio cholerae E7946 ATCC 55056

Subject, 958 a.a., 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) from Variovorax sp. SCN45

 Score =  994 bits (2569), Expect = 0.0
 Identities = 497/937 (53%), Positives = 645/937 (68%), Gaps = 13/937 (1%)

Query: 8   AWLESSHLAGANATYVEDLYELYLSDPDLVSEEWKRVFDGLPAHP----TNVVEQPHSRV 63
           A+  +++L G NA YVE++YE YLS+P  V + W+  FD L   P    TN  + PH  V
Sbjct: 12  AYQGNTYLFGGNAPYVEEMYENYLSNPGSVPDNWRSYFDALQNVPAADGTNTRDVPHLPV 71

Query: 64  RDYFRRLAQE--TKHYNVQVSDPEVDAKQVKVLQLINAYRFRGHEAAKLDPLGLWNRPEV 121
            + F   A++  TK      +D E+  K+  V QLI AYR  G   A LDPL    RP +
Sbjct: 72  INAFAERAKQGTTKVVQASGADSELGRKRTSVQQLIAAYRNVGARWADLDPLKRAERPAI 131

Query: 122 AELNPSFHNLTQEDMEETFNVGSFAIGKDTMKLKDIYQSLQKIYCGSVGAEYMHITDTEQ 181
            EL PSF+     D+E  FN  +   GK+TM L+D+  +L++ YCG++GAEYM+ TD   
Sbjct: 132 PELEPSFYGFADADLETVFNTSNTFFGKETMSLRDLLNALRETYCGTMGAEYMYTTDQNH 191

Query: 182 KRWIQQRLEPVVGTPVFSKEEKRTFLEELTAAEGLERYLGAKFPGAKRFSLEGGDALVPM 241
           KRW QQRLE     P  S E+K+  L  LTAAEGLER+L  K+ G KRFSLEGG++ +  
Sbjct: 192 KRWWQQRLESARTNPKLSAEQKKHVLNRLTAAEGLERFLHTKYVGQKRFSLEGGESFIVA 251

Query: 242 TKEMIRHAGASGMREVVIGMAHRGRLNMLVNVLGKKPQDLFDEFAGKHGEGWGTGDVKYH 301
             E+I  AG  G++E+VIGMAHRGRLN+LVN LGK P DLF EF     E   +GDVKYH
Sbjct: 252 MDELINQAGVKGVQEIVIGMAHRGRLNVLVNSLGKMPADLFAEFDHTAPEDLPSGDVKYH 311

Query: 302 QGFSADFATPGGDVHLALAFNPSHLEIVNPVVMGSVRARQDRLGDEDGSKVLPITIHGDS 361
           QGFS+D  TPGG VHL+LAFNPSHLEIVNPVV GSVRAR DR GD  G +VLP+ +HGD+
Sbjct: 312 QGFSSDVTTPGGPVHLSLAFNPSHLEIVNPVVEGSVRARMDRRGDPLGKQVLPVIVHGDA 371

Query: 362 AIAGQGVVAETFNMSQARGFCVGGTVRIVVNNQVGFTTSNPRDTRSTMYCTDIAKMVQAP 421
           A AGQGVV ET  +++ RG+  GGTV IV+NNQ+GFTTS+PRD+RST+YC+DI KM++AP
Sbjct: 372 AFAGQGVVMETLALAETRGYSTGGTVHIVINNQIGFTTSDPRDSRSTLYCSDIVKMIEAP 431

Query: 422 IFHVNSDDPEAVAFVTRLALDYRNEFKRDVVIDLVCYRRHGHNEADEPNATQPLMYQKIK 481
           + HVN DDPEAV   T++ALD+R EF++DVV+D++C+R+ GHNE D P+ TQPLMY+KI 
Sbjct: 432 VLHVNGDDPEAVVLATQIALDFRMEFQKDVVVDIICFRKLGHNEQDTPSLTQPLMYKKIA 491

Query: 482 KHPTPRKLYADVLTERGECDLETATQLVNEYRDALDHGEVVVKE--WRPMAMHSVDWSPY 539
           +HP  RKLYAD L  +G  D      +V   R A D G+  V        + ++VDWSPY
Sbjct: 492 QHPGTRKLYADKLAAQGLGD-TLGDDMVKAQRAAFDEGKNTVDPVLTNFKSKYAVDWSPY 550

Query: 540 LGHDWHIPWNSEYAMERLQDLGRRVCQYPESHVLHSRVEKIYQDRLSMISGEKMLDWGMA 599
           L   W    ++       + L  ++   P+   +H  V+K+  DR +M  G+  +DWGM 
Sbjct: 551 LNKKWTDAGDTAIPSSEWKRLAEKITAVPQGFTVHPLVKKVLDDRAAMGRGDVNIDWGMG 610

Query: 600 ETLAYATLLDDGKRIRISGQDSGRGTFFHRHAVLHNQN----DASTYIPLSQIHAGQGPF 655
           E +A+A+L+  G  +R+SG+DSGRGTF HRHAVLH+QN    D  TY PL  +   Q PF
Sbjct: 611 EHMAFASLVASGYPVRLSGEDSGRGTFTHRHAVLHDQNREKFDTGTYTPLQNVADNQAPF 670

Query: 656 EVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFANGAQVVIDQFISSGEQKWGRLC 715
            V DS+LSEEAVLAFEYGYA+ +P+ L +WEAQFGDF NGAQVVIDQFI+SGE KWGR+ 
Sbjct: 671 VVIDSILSEEAVLAFEYGYASNDPNTLVIWEAQFGDFVNGAQVVIDQFIASGEVKWGRVN 730

Query: 716 GLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVVVPSTPAQVYHMIRRQVVRPMRRP 775
           GLTM+LPHGYEGQGPEHSSARLER++QL A+ NMQVV P+T +Q++H++RRQ+VR +R+P
Sbjct: 731 GLTMMLPHGYEGQGPEHSSARLERFMQLSADTNMQVVQPTTASQIFHVLRRQMVRNLRKP 790

Query: 776 LVVMSPKSLLRHPLCVSSMEDLAHGTFQPAIGEIDALNPSQVKRVVFCSGKVYYDLLEQR 835
           L++++PKSLLR+    S + +   G+FQ  I +   L   +VKR++ CSGKVYYDL ++R
Sbjct: 791 LIILTPKSLLRNKDATSPLSEFTKGSFQTVIPDSKGLKADKVKRLIACSGKVYYDLAKKR 850

Query: 836 RANEQQDVAIVRIEQLYPFPLEEVQAAIANYTNVVDYVWCQEEPQNQGAWYSSQHNFRAA 895
                +DVAI+R+EQLYPFP +   A I  Y N+VD VWCQ+EPQNQGAW+  QH     
Sbjct: 851 EELGNEDVAIIRVEQLYPFPHKAFAAEIKKYPNLVDVVWCQDEPQNQGAWFFVQHYIHEN 910

Query: 896 IPAGADLKYAGRPASASPAVGYMSVHMKQQKALIEDA 932
           +  G  L Y+GR ASASPAVGY  +H +QQKAL++ A
Sbjct: 911 MQDGQKLGYSGRAASASPAVGYSHLHQEQQKALVDGA 947