Pairwise Alignments

Query, 666 a.a., NADPH-dependent 2,4-dienoyl-CoA reductase from Vibrio cholerae E7946 ATCC 55056

Subject, 662 a.a., 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) from Hydrogenophaga sp. GW460-11-11-14-LB1

 Score =  238 bits (606), Expect = 9e-67
 Identities = 200/706 (28%), Positives = 326/706 (46%), Gaps = 97/706 (13%)

Query: 2   YPNLFQPLDLGFTQLKNRVLMGSMHTGLEENKEGL--HKLAAFYEERAKGGVGLIVTGGF 59
           +P LF+P+ +G  ++KNR+ M  M      +  GL   +   ++ ERA+GGVGL++TG  
Sbjct: 5   FPKLFEPVRIGKVRMKNRIAMAPMGFPALSDFAGLPTQRYVDYFTERARGGVGLLLTGML 64

Query: 60  --------SPNLRGRLHPFSAEFSKTKHAKAHKVVTEAVHRHGAKIALQLLHAGRYAMHP 111
                   S   RG   P   EF      +    +TEA H  GAKI  QL     +   P
Sbjct: 65  KVEDNIEHSTRKRG---PIRDEF-----IRPFADLTEAAHALGAKIFGQLSAGFGHQARP 116

Query: 112 FSQSASAIRAP-IAKFAPSE-----MSTRQIRNTIQDFANSAELAQLAGYDGVEVMGSEG 165
            S     + A  I  F  +      ++T +++  ++ F N+AE+   AG DGVE+ G  G
Sbjct: 117 GSVRGGPVSASAIPNFGDTSVTCRALTTEEVQQLVKAFGNAAEIFARAGVDGVELHGHGG 176

Query: 166 YLINQFICKRTNMRYDEWGGSYQNRIRFPVEIVKAIREAVGKEFIIIFRLSML------- 218
           +L++QF     N R D++GG    R+RFP+E+++ I+  VG +F + +R  +        
Sbjct: 177 FLLDQFTTSLWNRRDDQYGGDLAARMRFPIEVLQEIKRRVGPDFPVTYRYGLKHYMKSFT 236

Query: 219 -------DLVEQGSTFEEVVVLAKALEEAGVTII----NTGIGWHEARIPTIATQVPRAA 267
                  + VE G   +E + +A+ L++AG   +     T  G + A  P          
Sbjct: 237 QAALPGENFVEVGRDIDEGLEMARRLQDAGFDALAVDAGTLAGHYWAHPPMYQKH---GC 293

Query: 268 FSWVTEKIKPYLKVPVVTCNRINTPEQAEKILASGQADMVSMARPFLADADFVRKAQEGQ 327
              +   +K  +++PV+   R++ P+ AE+ L  G+ADMVS+AR  LAD  +  K  +G+
Sbjct: 294 LLDMAAMVKEVVEIPVLAVGRLDIPDMAEQALVDGKADMVSLARGLLADPYWPTKVLQGR 353

Query: 328 SALINTCIGCNQACLDNVFRGKRASCLVNPRACYETEIVVKPAQ-SKKIAVVGAGPAGLA 386
              I  CIGC+QAC +     +  SC VNP A  E    ++PA+ ++ + VVG G AG+ 
Sbjct: 354 VDDIRPCIGCHQACTEAYNGREINSCTVNPAAGREKAYELRPAETARTVLVVGGGIAGME 413

Query: 387 FATTASERGHQVDLFERNDRIGGQFRLAMQIPGKEEFRETIRYFANRIDQTGVKLHLGCE 446
            A  ++ RGH V LFE+ D +GG    A     K++     +++  ++D+ GV + L  E
Sbjct: 414 AARVSATRGHAVTLFEKGDALGGHLLEAGVPDDKKDVERLNQWYLRQLDKLGVNVRLHTE 473

Query: 447 V--QFSDLRGYDEVVIATG---VTPRKIALAGLSESSKVVDYQTLIREKTPVGQKVAIVG 501
           V  +  +    + VV+A+G   V PR   L G+ +   +   + L+ EK P G +V +VG
Sbjct: 474 VTAELVERERPEVVVVASGSRDVVPR---LPGVHKPHVITTTEALL-EKKPTGARVVVVG 529

Query: 502 AGGIGVDVASMLTEPKDQTLDDWLYEWGIDKAIEHPGGLYPYPETTSEREVWLLQRRKGA 561
           AG  G + A             WL + G                    REV L++ +   
Sbjct: 530 AGENGCEAAL------------WLAKKG--------------------REVTLVEMQSRP 557

Query: 562 VGKGPGKTTGWIHKRTLEKRGVHLV----GGVQYQKIDEQGLHIERDGKSELIDADSVVI 617
           +     +         L+   +H +         + +D+  +  E+DG    ID D+VV+
Sbjct: 558 MAAPVARAN---KNMLLDSLALHQIPIRTDTTLMEVLDDAVMVKEQDGSLVRIDCDTVVL 614

Query: 618 CAGQESVRPFEAQ-WAELGDKLHVIGGADVAGELDAARAIRQGVEL 662
             G ++      Q    L   L+ IG  D     +  RAI +G E+
Sbjct: 615 AVGLKADDQLHQQLMGSLAAPLYAIG--DCQEPRNIMRAIWEGFEV 658