Pairwise Alignments

Query, 388 a.a., mannose-6-phosphate isomerase, class I from Vibrio cholerae E7946 ATCC 55056

Subject, 391 a.a., mannose-6-phosphate isomerase (VIMSS) from Escherichia coli BW25113

 Score =  345 bits (885), Expect = 1e-99
 Identities = 189/390 (48%), Positives = 254/390 (65%), Gaps = 7/390 (1%)

Query: 1   MTNPIQNYAWGSKTALQQLFELENPNDDPQAELWMGAHPNGCSGIA-INGKIVQLSDFIA 59
           + N +QNYAWGSKTAL +L+ +ENP+  P AELWMGAHP   S +    G IV L D I 
Sbjct: 4   LINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKSSSRVQNAAGDIVSLRDVIE 63

Query: 60  QNPNLILGEYTARQFGELPYLFKILAAEKALSIQVHPNKQQAERGFAQEEQLGIALTAAQ 119
            + + +LGE  A++FGELP+LFK+L A + LSIQVHPNK  +E GFA+E   GI + AA+
Sbjct: 64  SDKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNKHNSEIGFAKENAAGIPMDAAE 123

Query: 120 RNYKDPNHKPELVYALTEYQAMNGFRANQEILNYFIELSIDEIQPLVNVFQSNPTEQGLR 179
           RNYKDPNHKPELV+ALT + AMN FR   EI++    ++     P +  F   P  + L 
Sbjct: 124 RNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQPVA--GAHPAIAHFLQQPDAERLS 181

Query: 180 DFFSGLLSLQGEAKNRALEALMAQAKQIDLPLFQLIVELENQYPNDIGLFAPLMLNVITL 239
           + F+ LL++QGE K+RAL  L +         +Q I  +   YP D GLF+PL+LNV+ L
Sbjct: 182 ELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIRLISEFYPEDSGLFSPLLLNVVKL 241

Query: 240 QPGEAMFLDAETPHAYLHGTGLEIMANSDNVLRAGLTPKYMDIDELVACTQFKHKPLEQL 299
            PGEAMFL AETPHAYL G  LE+MANSDNVLRAGLTPKY+DI ELVA  +F+ KP  QL
Sbjct: 242 NPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAGLTPKYIDIPELVANVKFEAKPANQL 301

Query: 300 RLKPEVIEGCE-QYPIPVADFKFAIIPPTTQQ-TIGVKSAEVVLPLDSSMILRHANGEQC 357
             +P V +G E  +PIPV DF F++   + ++ TI  +SA ++  ++    L     +Q 
Sbjct: 302 LTQP-VKQGAELDFPIPVDDFAFSLHDLSDKETTISQQSAAILFCVEGDATL-WKGSQQL 359

Query: 358 LVRKGQSVFIPAYAEQYTIECNGRVARAFS 387
            ++ G+S FI A     T++ +GR+AR ++
Sbjct: 360 QLKPGESAFIAANESPVTVKGHGRLARVYN 389