Pairwise Alignments
Query, 922 a.a., insulinase family protein from Vibrio cholerae E7946 ATCC 55056
Subject, 914 a.a., Predicted Zn-dependent peptidases from Kangiella aquimarina DSM 16071
Score = 100 bits (248), Expect = 5e-25
Identities = 184/912 (20%), Positives = 348/912 (38%), Gaps = 92/912 (10%)
Query: 37 LPNGLTYHLYPDSEQE-VSIRLYVHAGSMQETAQQAGYAHFIEHMAFNGTRHYQHNDVIR 95
L NGL L+PD QE +++ + H GS E + G AH +EH+ F GT +++
Sbjct: 43 LDNGLQVLLFPDPTQESITVNITYHVGSKHENYGETGMAHLLEHLVFKGTPDHKN----- 97
Query: 96 MFEQSGAQFGADFNALTGYDRT-VYQLDLPNAQNIDKALLWFADIADGLAFDADEVEKEK 154
Q ++ GA+ N T DRT Y+ N++ AL +D ++++ E
Sbjct: 98 -IPQELSERGAEPNGTTWLDRTNYYETFAATEDNLNWALDLESDRMINSFIAKEDLDSEM 156
Query: 155 GVILGEFRASRTENMSLEQQFYLHQIQGTSYADRDPLGSRELVQAATPDSLKAFYQQWYQ 214
V+ E M + Q + + +G+R ++ +L+AFY+++YQ
Sbjct: 157 TVVRNELENGENSPMRVLMQRLMSVAYDWHNYGKSTIGARSDLENVDIKNLQAFYKKYYQ 216
Query: 215 PQLAELVITGNFTLEQGQQWVENYFSSWKKGSTEKPASIYHQALNNQDLVAPV-TAGESP 273
P A L+I G E + V+ YF KK P + + + + + G+
Sbjct: 217 PDNATLIIAGKIDEESTIKKVDKYFGDIKKPKRILPELYTEEPIQDGERKVIIRRTGDVQ 276
Query: 274 SLTLIFPQGSAAIKDYASQQEFWRDDVGEQLLHTRLVAAFNDAAQAITGIYATHYEIEGQ 333
+ ++ + DYA+ Q + Q R D A A G +A G
Sbjct: 277 VVGGLYKTPAGPHADYAAVQILSQIMGDSQTGRLRKELVEKDLA-ASAGGFAFQLAEPG- 334
Query: 334 RYTLISVGFAAEQRE--KVQALLLETLASMRDYGVTKNELD----IILRGYREHLTFLQE 387
L+ + A+ ++ K +A ++ + + + +T+ E++ +L+G L+F
Sbjct: 335 --ALLFMAQVAKDKDLAKTEAAFVDVIEGVANNPITEEEVERAKTKLLKGI--ELSFNNT 390
Query: 388 DREAITPASHANQKVYSIVFDTPIQATLDYQASLSEFIASATPEMINRHIQQQLSQNPVW 447
A+ + ++F + + T E + + ++ L +
Sbjct: 391 QSVALQLTEWVGMGDWRLLFLN------------RDRLEKVTAEDVQKAAEEYLVNDNRT 438
Query: 448 VVGVAATEDAQALNKALPQWRNDLAQPGNQPIDQQIDSPFTQQFTA-GEVVKQLDINDDP 506
V A + + P + +A+ ++ I + ++ ++ A GE N D
Sbjct: 439 V--------ALFIPEEKPDRADSIARLNSEDIQKMLEGYTGREAVAQGEDFDASYDNIDA 490
Query: 507 QVTYWQLDNGIDVYYLRNIEAKDRVFVQYASSGGQFALPADLLPAAEIATAVQTRSGLDT 566
+ L NG V YL + V + G DL A + + + T
Sbjct: 491 RSERTTLSNGAKVVYLPKKTRGESVVMTINLDIGNL---DDLRNAGVVPSLTSSMLMRGT 547
Query: 567 LN------GSQFDRYLRQKDIGFYSYIASTSHGFEANSKAQELPELLEILHLLSTQVKVS 620
N ++FDR + +TS G + + LP++LE++ + Q
Sbjct: 548 ENFTREELQAEFDRLKANVSVSG----GATSTGVRIQTVKENLPKVLELVEEVLKQPAFD 603
Query: 621 PDQLNSVKTEFTQNRSAYFDSPIGAFFRTVTNQSFIETSP----YRIRTPEQIAQVTAQQ 676
+L +K + P F + NQ P Y + EQI + A +
Sbjct: 604 QKELEVLKKQQIVALEQQKQQPQTQVFLQL-NQHLNPYDPSHPLYSMSIDEQIEAIKAVE 662
Query: 677 IE--QVHQRLFSEGRNNTLVIVGDIER----SQITPMLRQYVASIPLSKGTLSPMTSQLI 730
++ + F + + +VGD ER Q+ +L + A + + S + I
Sbjct: 663 VDNLKAFHSNFIGAKEADIAVVGDFERDSLHKQLDSILGNWDADVEYKRIERSVADVEAI 722
Query: 731 K-----------PVAPRLELALNNENSTQYSLRLISETQPRTAKTVFIDDMLQRIATQRL 779
A +L L++++ +L++ +E +F L RL
Sbjct: 723 NKFIDTPDKAGAAFAAMTKLELSDQHPDYAALKMANE--------IFGGGFL----NSRL 770
Query: 780 LAEVREHQGLDYTPQVIPYVVDGDILNDWVLSALVDPKSEPQV-AKVMHEVARELAQGVT 838
+R+ GL Y D + A+ P++ P+V E+ R L G T
Sbjct: 771 ATRLRQKDGLSYGAGSFFSASSYDENATFGAYAIAAPENLPRVEVGFKEELERALKDGFT 830
Query: 839 QQELDVVKQKFLIDMKPLNKSPEQQAYFMLRYAIH-HYGVETIYKVEELTKSITLDDINQ 897
Q+ELD + L + + +++S + + L ++ +E + EE K++TL D+N
Sbjct: 831 QEELDKARDGVLQNNR-IDRSKDARLVSSLAGSLDLERTMEWSKEYEEKLKALTLKDVND 889
Query: 898 RAQTLFGKDTMS 909
+ D +S
Sbjct: 890 AFRRHIKMDNIS 901
Score = 38.9 bits (89), Expect = 2e-06
Identities = 85/439 (19%), Positives = 173/439 (39%), Gaps = 42/439 (9%)
Query: 29 DQRWVTQTLPNGLTYHLYPDSEQEVSIRLYVHA--GSMQETAQQAGYAHFIEHMAFNGTR 86
D R TL NG P + S+ + ++ G++ + M GT
Sbjct: 489 DARSERTTLSNGAKVVYLPKKTRGESVVMTINLDIGNLDDLRNAGVVPSLTSSMLMRGTE 548
Query: 87 HYQHNDVIRMFEQSGAQFGADFNALTGYDRTVYQLDLPNAQNIDKALLWFADIADGLAFD 146
++ ++ F++ A+ + G T ++ +N+ K L ++ AFD
Sbjct: 549 NFTREELQAEFDR----LKANVSVSGGATSTGVRIQTVK-ENLPKVLELVEEVLKQPAFD 603
Query: 147 ADEVE---KEKGVILGEFRASRTENMSLEQQFYLHQIQGTSYADRDPLGSR------ELV 197
E+E K++ V L + + + L+ +L+ Y PL S E +
Sbjct: 604 QKELEVLKKQQIVALEQQKQQPQTQVFLQLNQHLNP-----YDPSHPLYSMSIDEQIEAI 658
Query: 198 QAATPDSLKAFYQQWYQPQLAELVITGNFTLEQGQQWVENYFSSWKKGSTEK--PASIYH 255
+A D+LKAF+ + + A++ + G+F + + +++ +W K S+
Sbjct: 659 KAVEVDNLKAFHSNFIGAKEADIAVVGDFERDSLHKQLDSILGNWDADVEYKRIERSVAD 718
Query: 256 QALNNQDLVAPVTAGES-PSLTLIFPQGSAAIKDYASQQEFWRDDVGEQLLHTRLVAAF- 313
N+ + P AG + ++T + + S DYA+ + + G L++RL
Sbjct: 719 VEAINKFIDTPDKAGAAFAAMTKL--ELSDQHPDYAA-LKMANEIFGGGFLNSRLATRLR 775
Query: 314 -NDAAQAITGIY--ATHYEIEGQRYTLISVGFAAEQREKVQALLLETLASMRDYGVTKNE 370
D G + A+ Y+ E + ++ A E +V+ E L G T+ E
Sbjct: 776 QKDGLSYGAGSFFSASSYD-ENATFGAYAIA-APENLPRVEVGFKEELERALKDGFTQEE 833
Query: 371 LDIILRGYREHLTFLQEDREAITPASHANQKVYSIVFDTPIQATLDYQASLSEFIASATP 430
LD G LQ +R S + V S+ ++ T+++ E + + T
Sbjct: 834 LDKARDG------VLQNNR---IDRSKDARLVSSLAGSLDLERTMEWSKEYEEKLKALTL 884
Query: 431 EMINRHIQQQLSQNPVWVV 449
+ +N ++ + + + ++
Sbjct: 885 KDVNDAFRRHIKMDNISII 903