Pairwise Alignments

Query, 922 a.a., insulinase family protein from Vibrio cholerae E7946 ATCC 55056

Subject, 962 a.a., protease III from Escherichia coli BL21

 Score = 74.3 bits (181), Expect = 3e-17
 Identities = 141/717 (19%), Positives = 263/717 (36%), Gaps = 54/717 (7%)

Query: 19  LQQTNRALQPDQR-WVTQTLPNGLTYHLYPDSEQEVSIR-LYVHAGSMQETAQQAGYAHF 76
           +Q+T R    D R +    L NG+   L  D +   S+  L V  GS+++     G AH+
Sbjct: 30  IQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHY 89

Query: 77  IEHMAFNGTRHYQHNDVIRMFEQSGAQFGADFNALTGYDRTVYQLDLPNAQNIDKALLWF 136
           +EHM+  G++ Y   D +  + +     G   NA T   RT + L++ N   +  A+   
Sbjct: 90  LEHMSLMGSKKYPQADSLAEYLK---MHGGSHNASTAPYRTAFYLEVEN-DALPGAVDRL 145

Query: 137 ADIADGLAFDADEVEKEKGVILGEFRASRTENMSLEQQFYLHQIQGTSYADRDPLGSREL 196
           AD       D    E+E+  +  E   +RT +     Q     I       +   G+ E 
Sbjct: 146 ADAIAEPLLDKKYAERERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLET 205

Query: 197 VQ----AATPDSLKAFYQQWYQPQLAELVITGNFTLEQGQQWVENYFSSWKKGSTEKPAS 252
           +          +LK F++++Y   L + VI  N  L +  +   + F       ++KP  
Sbjct: 206 LSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEI 265

Query: 253 IYHQALNNQDLVAPVTAGESPSLTLIFPQGSAAIKDYASQQEFWRDDVGEQLLHTRLVAA 312
                 + Q     +     P+L     +    I + +++     D++   L+  R    
Sbjct: 266 TVPVVTDAQ---KGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGT 322

Query: 313 FNDAAQ---AITGIYATHYEIEGQRYTLISVGFA-----AEQREKVQALLLETLASMRDY 364
            +D  Q    + GI A    I      ++++  +        R++V A +   L  +R+ 
Sbjct: 323 LSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREK 382

Query: 365 GVTKNELDIILRGYREHLTFLQEDREAITPASHANQKVYSIVFDTPIQATLDYQASLSEF 424
           G+ K   D +      ++  +     +IT      + +   +   P++ TLD       +
Sbjct: 383 GIDKQYFDEL-----ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRY 437

Query: 425 IASATPEMINRHIQQQLSQNPVWVVGVAATEDAQALNKALPQWRNDL-----AQPGNQPI 479
            A A  E +     Q      +W +      +  A     P   + +     A    +  
Sbjct: 438 DAKAVKERLAMMTPQNAR---IWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAA 494

Query: 480 DQQIDSPFTQQFTAGE--VVKQLDINDDPQVTYWQLDNGIDVYYLRNIEAKDRVFVQYAS 537
           D  +  P    +   +  ++K     D P++        +D   LR + A  R F     
Sbjct: 495 DIALSLPELNPYIPDDFSLIKSDKKYDHPELI-------VDESNLRVVYAPSRYFASEPK 547

Query: 538 SGGQFALPADLLPAAEIATAVQTRSGL-DTLNGSQFDRYLRQKDIGFYSYIASTSHGF-- 594
           +     L     P A  +   Q    L D L G   D+   Q  +G  S+  + ++G   
Sbjct: 548 ADVSLILRN---PKAMDSARNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMV 604

Query: 595 EANSKAQELPELLEILHLLSTQVKVSPDQLNSVKTEFTQNRSAYFDSPIGAFFRTVTNQS 654
            AN   Q LP+L + L         + DQL   K+ + Q   +       AF + +    
Sbjct: 605 NANGYTQRLPQLFQALLEGYFSYTATEDQLEQAKSWYNQMMDSAEKGK--AFEQAIMPAQ 662

Query: 655 FIETSPYRIRTPEQ--IAQVTAQQIEQVHQRLFSEGRNNTLVIVGDIERSQITPMLR 709
            +   PY  R   +  +  +T +++      L S G     +++G++  +Q T + R
Sbjct: 663 MLSQVPYFSRDERRKILPSITLKEVLAYRDALKS-GARPEFMVIGNMTEAQATTLAR 718