Pairwise Alignments

Query, 305 a.a., HTH-type transcriptional regulator MetR from Vibrio cholerae E7946 ATCC 55056

Subject, 317 a.a., DNA-binding transcriptional activator, homocysteine-binding (NCBI) from Escherichia coli BW25113

 Score =  349 bits (896), Expect = e-101
 Identities = 172/303 (56%), Positives = 224/303 (73%), Gaps = 4/303 (1%)

Query: 1   MIELKHLKTLISLRDTGSLTATATSLHLTQSALSHQIKDLEARIGGQLFLRKTRPVRFTA 60
           MIE+KHLKTL +LR+ GSL A A +LH TQSALSHQ  DLE R+G +LF+RK++P+RFT 
Sbjct: 1   MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTP 60

Query: 61  EGEILLRLADDILPKMSRAENELASLKEDVNGRLHMAIECHSCFQWLMPALREYQVSWPN 120
           +GEILL+LA+ +LP++S+A   L +  E    RL +AIECHSC QWL PAL  +  +WP 
Sbjct: 61  QGEILLQLANQVLPQISQA---LQACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQ 117

Query: 121 VALDFSSGFGFEPLPALLAGELDLVITSDILPRSEVHYEPLFDFEMRLITATNHPLADKA 180
           V +DF SG  F+P PAL  GELDLV+TSDILPRS +HY P+FD+E+RL+ A +HPLA K 
Sbjct: 118 VEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDYEVRLVLAPDHPLAAKT 177

Query: 181 GIEPQDLADQTMLTYPVQKQRLDVVKHFLQPAGVEPARWKQADNTLMLVQMVSAGLGVAA 240
            I P+DLA +T+L YPVQ+ RLDV +HFLQPAGV P+  K  DNTL+L+QMV+A +G+AA
Sbjct: 178 RITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPS-LKSVDNTLLLIQMVAARMGIAA 236

Query: 241 LPNWAISEFSRQGLITSKPLGKGLWRRLFAATRHSEKDKRYLQAFFATARQQCKSHLDGI 300
           LP+W +  F RQGL+ +K LG+GLW RL+AA R  E+ +   +AF  +AR     HL  +
Sbjct: 237 LPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQPVTEAFIRSARNHACDHLPFV 296

Query: 301 KMA 303
           K A
Sbjct: 297 KSA 299