Pairwise Alignments

Query, 461 a.a., class II fumarate hydratase from Vibrio cholerae E7946 ATCC 55056

Subject, 465 a.a., Fumarate hydratase class II (EC 4.2.1.2) from Variovorax sp. SCN45

 Score =  371 bits (952), Expect = e-107
 Identities = 203/456 (44%), Positives = 284/456 (62%), Gaps = 6/456 (1%)

Query: 6   RIEKDSMGEVKVPADALYQAQTQRAVDNFTLSRYTMPSAFIAALAYIKQAAAMTNAQLGH 65
           R E+D+ G + VPAD L+ AQTQR++ NF +S    P   I ALA +K+A+A+ N  LG 
Sbjct: 8   RAERDTFGPIDVPADKLWGAQTQRSLQNFDISGEQQPREIIKALAQVKRASAVVNHALGL 67

Query: 66  LEGDIAQAIANASQAVIDGQYAKQFPIDVFQTGSGTSSNMNANEVIATLASRELG----- 120
            +     AI  A+  VI G++  +FP+ V+QTGSGT +NMN NEV+A  AS  LG     
Sbjct: 68  QDEKKTGAIVAAADEVIAGKHPGEFPLVVWQTGSGTQTNMNVNEVLANRASELLGGERGE 127

Query: 121 -YAVSPNDHVNMGQSSNDVIPTAIQVSAAINIEQQLLPALAHLSQTLADKQSELADVVKT 179
              V PND VN  QSSNDV PTA+ V+A   I  +LLPA+A L  TL  K  + AD+VK 
Sbjct: 128 GRLVHPNDDVNRSQSSNDVFPTAMHVAAVEAITHKLLPAIAKLRGTLEQKSKDFADIVKI 187

Query: 180 GRTHLMDAMPVTFAQELGGWKSQIDHAAQGISHALSPIKALAQGGTAVGTGINADPRFAR 239
           GRTHL DA P+T  QE  G+ +Q+ +    +  AL  +  LA GGTAVGTG+NA   +A 
Sbjct: 188 GRTHLQDATPLTLGQEFSGYVAQLANGEAHVRAALPHLSELALGGTAVGTGLNAPKGYAE 247

Query: 240 IFADNLSQLSHVAFQPSDNFFYNLSSQDCVVGLSGQLKTAAVALMKIANDLRWMNSGPLA 299
             A  L++++ + F  + N F  ++S D +V   G LKT A ++ KIAND+RW+ SGP +
Sbjct: 248 QVAAELAKITGLPFVTAPNKFEAMASVDALVHAHGALKTLAASMNKIANDVRWLASGPRS 307

Query: 300 GLGEIELQGLQPGSSIMPGKVNPVIPEAVTMVAAQVIGNDTTITVAGQSGNFQLNVMLPV 359
           G+GE+ +   +PGSSIMPGKVNP   EAVTM+AAQV GND  I + G SGNF+LNV  P+
Sbjct: 308 GIGELSIPENEPGSSIMPGKVNPTQSEAVTMLAAQVFGNDVAINIGGASGNFELNVFRPM 367

Query: 360 IAHNLLESIELLTNACHALADKAIATFKVRHDNLEKALAKNPILVTALNPVIGYLKAADI 419
           +AHN L+S+ LL +   +  D      +   + + + + ++ +LVTALN  IGY K+A I
Sbjct: 368 VAHNFLQSVRLLADGMVSFNDHCAVGIEPNRERITELVQRSLMLVTALNTHIGYDKSAYI 427

Query: 420 AKKAYQQGRAILDVAAEETDLDRATLEALLDPKKLT 455
           AKKA+++G ++ + A     L     +A + P+ +T
Sbjct: 428 AKKAHKEGTSLREAAIASGHLTAEQFDAWVVPENMT 463