Pairwise Alignments

Query, 457 a.a., multidrug resistance protein NorM from Vibrio cholerae E7946 ATCC 55056

Subject, 457 a.a., multidrug efflux MATE transporter MdtK from Escherichia coli ECRC62

 Score =  500 bits (1288), Expect = e-146
 Identities = 254/458 (55%), Positives = 339/458 (74%), Gaps = 2/458 (0%)

Query: 1   MHRYKKEASNLIKLATPVLIASVAQTGMGFVDTIMAGGVSAIDMAAVSIAASIWLPSILF 60
           + +Y  EA  L+ LA PV++A +AQT MGFVDT+MAGG SA DMAAV+I  SIWLP+ILF
Sbjct: 1   VQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILF 60

Query: 61  GVGLLMALVPVVAQLNGAGRQHKIPFEVHQGLILALLVSVPIIAVLFQTQFIIRFMD-VE 119
           G GLL+AL PV+AQLNG+GR+ +I  +V QG  LA  VSV I+ VL+   +IIR M+ ++
Sbjct: 61  GHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENID 120

Query: 120 EAMATKTVGYMHAVIFAVPAYLLFQALRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVY 179
            A+A K VGY+ A+++  P YL FQ  R+  +G++ TKP MV+GFIGLL+NIP+N+IF+Y
Sbjct: 121 PALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIY 180

Query: 180 GKFGAPELGGVGCGVATAIVYWIMLLLLLFYIVTSKRLAHVKVFETFHKPQPKELIRLFR 239
           G FG PELGGVGCGVATA VYW+M L ++ YI  ++ +  ++  +   KP P  + RL +
Sbjct: 181 GHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQ 240

Query: 240 LGFPVAAALFFEVTLFAVVALLVAPLGSTVVAAHQVALNFSSLVFMFPMSIGAAVSIRVG 299
           LG P+A ALFFEVTLFAVVALLV+PLG   VA HQ+ALNFSSL+F+ PMS+ AAV+IRVG
Sbjct: 241 LGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVG 300

Query: 300 HKLGEQDTKGAAIAANVGLMTGLATACITALLTVLFREQIALLYTENQVVVALAMQLLLF 359
           ++LG+  T  A  AA  GLM G+  A +TA+ TV  REQIALLY +N  VV LA  L+L 
Sbjct: 301 YRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLL 360

Query: 360 AAIYQCMDAVQVVAAGSLRGYKDMTAIFHRTFISYWVLGLPTGYILGMTNWLTEQPLGAK 419
           AA+YQ  D++QV+ +G LRGYKD  +IF+ TF +YWVLGLP+GYIL +T+ L  +P+G  
Sbjct: 361 AAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTD-LVVEPMGPA 419

Query: 420 GFWLGFIIGLSAAALMLGQRLYWLQKQSDDVQLHLAAK 457
           GFW+GFIIGL++AA+M+  R+ +LQ+    + L  A++
Sbjct: 420 GFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR 457