Pairwise Alignments

Query, 951 a.a., formate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 813 a.a., Formate dehydrogenase O alpha subunit (EC 1.2.1.2) @ selenocysteine-containing from Variovorax sp. SCN45

 Score =  163 bits (412), Expect = 5e-44
 Identities = 126/443 (28%), Positives = 193/443 (43%), Gaps = 91/443 (20%)

Query: 210 MTNSFNDMHNCKSMLFIGSNPAEAHPVAMQHILIAKEKNSCKIVVADPRRTRTAAKADYF 269
           MTN + D+ N   +L +G N AEAHP   + ++ AK++N  ++VV DPR TR+AA ADY+
Sbjct: 1   MTNHWQDIQNADVVLIMGGNAAEAHPCGFKWVIEAKKQNKARLVVVDPRFTRSAAMADYY 60

Query: 270 VSLRPGSDVAFIWGVLWHVFKNNWEDKEYIRQRV-------------------------- 303
             +R GSD+AF+ GV+ ++  N     EY+R                             
Sbjct: 61  APVRAGSDIAFLSGVINYLLSNEKIQMEYVRNYTNAPFIVGPDYKFEDGIFSGYNAEKRN 120

Query: 304 -------FGMDE-------------------IRAEVAKWTPAEVERVTGVSEEEVYNT-- 335
                  + +DE                   ++   A++TP  V R+TG  +++      
Sbjct: 121 YDPKSWNYALDEQGMAKVDMTMQDPQCVLQVMKRHYARYTPEMVSRITGTPQDKFLKVCE 180

Query: 336 --AKTLAENRPGCVVWCMGGTQHTTGNNNTRAYCILELALGNIGKSGGGANIFRGHDNVQ 393
             A T    R   +++ +G TQH+ G+   R   I++L LGNIG +GGG N  RGH N+Q
Sbjct: 181 YIASTSTSTRTMTIMYALGWTQHSQGSQMIRTGAIVQLLLGNIGVAGGGMNALRGHSNIQ 240

Query: 394 GATDLGVLSDTLPGYYGLTEGSWKHWASVWGVDFEWIKN-RFDQGTYNGALPMETPGIPV 452
           G TDLG+LS++LPGY  L   S +     +      +K  R +Q +Y    P     +  
Sbjct: 241 GLTDLGLLSNSLPGYMSLARDSEQTLDDYYKT--RALKPLRPNQMSYWQNYPKFFVSMQK 298

Query: 453 SRWIDGVLENKD-------------------NLQQRENIRAMFYWG-HAVNSQTRGVEMK 492
           S W D    + D                    L  +  +      G + V S     ++ 
Sbjct: 299 SWWGDAATADNDWAFHYLPKIDKLYDVLQAFELMNQGKLNGYICQGFNPVGSFPDKKKIV 358

Query: 493 KAMQKLDMMVIVDPYPTVAAVM------------NDRTDGVYLLPATTQFETYGSVTASN 540
             + KL  +V +DP  T  +               D    V+ LP+T   E  GS+T S+
Sbjct: 359 DGLSKLKFLVTIDPLVTETSEFWRNFGEFNDVKTADIQTTVFRLPSTCFAEEDGSLTNSS 418

Query: 541 RSIQWRDQVIEPLFESKPDHEIM 563
           R +QW  +  EP  E+K D EI+
Sbjct: 419 RWLQWHWKGAEPPGEAKGDIEIV 441



 Score = 40.0 bits (92), Expect = 6e-07
 Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 15/123 (12%)

Query: 814 EYPIILTSGRLVEYEGGGEETRSNPWLAELQQEMFVEVNPKDANDLGFMDGDMVWVEGAE 873
           ++P + TS RL E+      T++    A +Q + FVE+  + A + G   GDMV V  ++
Sbjct: 685 DFPYVATSYRLTEHFHYW--TKNVRTSAIIQPQQFVEIGEELAKEKGIGHGDMVKV-SSK 741

Query: 874 KGRIKVKAMVTRRV--------KPGMAFLPFHFGGKFQGEDLRPKYPEGTQPYVVGEAAN 925
           +G IK  A+VT+R+              LP H+G  F G   +P Y   T    VG+ AN
Sbjct: 742 RGYIKAVAVVTKRIVGLQVDGRTVHTVGLPNHWG--FVGV-AKPGYLVNTLTPFVGD-AN 797

Query: 926 TAT 928
           T T
Sbjct: 798 TQT 800