Pairwise Alignments

Query, 951 a.a., formate dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 715 a.a., formate dehydrogenase alpha subunit (EC 1.2.1.2) from Enterobacter asburiae PDN3

 Score =  246 bits (629), Expect = 3e-69
 Identities = 162/516 (31%), Positives = 267/516 (51%), Gaps = 41/516 (7%)

Query: 66  TICSHCSVGCGIYAEVQNGVWTGQEPAFDHPFNAGGHCAKGAALREHGHGER----RLKY 121
           T+C +C+ GC I+  V NG     E A     N G  C KG    +  +  +    RLK 
Sbjct: 6   TVCPYCASGCKIHLVVDNGKIVRAEAA-QGKTNQGTLCLKGYYGWDFINDTQILTPRLKT 64

Query: 122 PM--KLEGGKWKKISWEQAINEIGDKALKIREESGPDSVYFLGSAKHS-NEQAYLFRKMA 178
           PM  +  GGK + +SW +A++ +  +   I+ + GPD++   GS++ + NE  Y+ +K A
Sbjct: 65  PMIRRERGGKLEAVSWSEALDYVATRLSAIKAKYGPDAIQTTGSSRGTGNETNYVMQKFA 124

Query: 179 -SLWGTNNVDHQARICHSTTVAGVANTWGYGAMTNSFNDMHNCKSMLFIGSNPAEAHPVA 237
            ++ GTNNVD  AR+ H  +VAG+  + G GAM+N+ N++ N   +   G NPA++HP+ 
Sbjct: 125 RAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNAINEIDNTDLVFIFGYNPADSHPIV 184

Query: 238 MQHILIAKEKNSCKIVVADPRRTRTAAKADYFVSLRPGSDVAFIWGVLWHVFKNNWEDKE 297
             H++ AK+ N  KI+V DPR+  TA  AD  ++L+ GS++A +  +   + + N  D+ 
Sbjct: 185 ANHVIRAKQ-NGAKIIVCDPRKIETARIADMHIALKNGSNIALLNAMGHVIIEENLYDQA 243

Query: 298 YIRQRVFGMDEIRAEVAKWTPAEVERVTGVSEEEVYNTAKTLAENRPGCVVWCMGGTQHT 357
           ++  R  G +E R  V  +TP  VE +TGVS +E+   A+  A  +   ++W MG TQ  
Sbjct: 244 FVATRTEGFEEYRKIVEGYTPESVETITGVSAQEIRQAARMYAGAKTAAILWGMGVTQFY 303

Query: 358 TGNNNTRAYCILELALGNIGKSGGGANIFRGHDNVQGATDLGVLSDTLPGY-YGLTEGSW 416
            G    R+   L +  GN+GK+  G N  RG +NVQGA D+G L DT PGY Y     + 
Sbjct: 304 QGVETVRSLTSLAMLTGNLGKAHVGVNPVRGQNNVQGACDMGALPDTYPGYQYVKFPENR 363

Query: 417 KHWASVWGVDFEWIKNRFDQGTYNGALPMETPGIPVSRWIDGVLENKDNLQQRENIRAMF 476
           + +A  WGV+               +LP  T G  +S           +      +RA +
Sbjct: 364 EKFAKAWGVE---------------SLPEHT-GYRIS--------ELPHRAAHGEVRAAY 399

Query: 477 YWGH-AVNSQTRGVEMKKAMQKLDMMVIVDPYPTVAAVMNDRTDGVYLLPATTQFETYGS 535
             G   + +      ++K  + L+++++ D + T  A   D      +LP+T+  E  G 
Sbjct: 400 IMGEDPLQTDAELSAVRKGFEDLELVIVQDIFMTKTAAAAD-----VILPSTSWGEHEGV 454

Query: 536 VTASNRSIQWRDQVIEPLFESKPDHEIMYLLSQKLG 571
            TA++R  Q   + +EP ++ K D +I+  ++ ++G
Sbjct: 455 YTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMG 490



 Score = 43.9 bits (102), Expect = 4e-08
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 814 EYPIILTSGRLVEYEGGGEETRSNPWLAELQQEM-FVEVNPKDANDLGFMDGDMVWVEGA 872
           EYP++L++ R V +      T +   LA L  E  + ++N  DA  LG  D  +VWV  +
Sbjct: 572 EYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTADAERLGIEDEALVWV-NS 630

Query: 873 EKGRIKVKAMVTRRVKPGMAFLPFHF 898
            KGRI  +A V+ R   G  ++ + +
Sbjct: 631 RKGRIITRAQVSDRPNKGAVYMTYQW 656