Pairwise Alignments

Query, 708 a.a., ribosomal RNA large subunit methyltransferase K/L from Vibrio cholerae E7946 ATCC 55056

Subject, 754 a.a., 50S rRNA methyltransferase from Pseudomonas simiae WCS417

 Score =  588 bits (1517), Expect = e-172
 Identities = 324/742 (43%), Positives = 439/742 (59%), Gaps = 50/742 (6%)

Query: 11  GLENLLVEELTQLGINDAKPVQAGVKFKATNEQIYRCCLWSRLASRFVRIVAEFKCQNDL 70
           GLE LL+EE   LG+ +A+   + V+  A  E  YR CLWSRLA+R + ++  F  ++  
Sbjct: 14  GLEGLLIEEAVGLGLEEAREHTSAVRGMADMETAYRLCLWSRLANRVLLVLKRFPMKDAE 73

Query: 71  DLYLSTTSVNWVNYFHSSKKLVVDFNGTNREIRNSQYGAMKVKDAIVDCFTKKNLPRPSI 130
           DLY     + W ++      L V+F+G    I N+ +GA+KVKDAIVD        RPSI
Sbjct: 74  DLYHGVLDIEWADHMVPDGTLAVEFSGHGSGIDNTHFGALKVKDAIVDKLRTPTGERPSI 133

Query: 131 SKDLADLHIHVRLHKENALLGIDMVGSGLHARGYRTEAGKAPLRETLAAAIILRSGWDA- 189
            K   DL IH+RL +  A+L +D+ G  LH RGYR + G APL+E LAAAI++R+GW   
Sbjct: 134 DKINPDLRIHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAILIRAGWPRI 193

Query: 190 ---SKPLLDPMCGSGTLLIEAAMMAANIAPGLQRKKWGFEALEDFEPELWASVKSEASVQ 246
                 L DPMCG GT L+E AM+AA++AP L R+ WGF       P LW  + +EA+ +
Sbjct: 194 AAEGGALSDPMCGVGTFLVEGAMIAADMAPNLNRELWGFTTWLGHVPALWKKLHAEAAER 253

Query: 247 GKRGVKKVETHFYGVDNDNRVLQTAKDNARRAGVEELISFTLGDAAKVK-RPENFAEGIV 305
              G+ K      G + D R++Q A++N  RAG+   I    G+    + RP+   +G+V
Sbjct: 254 AAVGMNKPPLWIRGYEADPRLIQPARNNIERAGLSHWIKVYQGEVGTFEPRPDQNQKGLV 313

Query: 306 ICNPPYGERLGTHPGLIALYTAFGAQLKAEFGGCHASIFSSSDELLSCLRMRADKQFKLN 365
           ICNPPYGERLG    L+ LY   G +L+    G  A++F+ + +L   + +R+ KQ+   
Sbjct: 314 ICNPPYGERLGDEASLLYLYQNLGERLRQACMGWEAAVFTGAPDLGKRMGIRSHKQYSFW 373

Query: 366 NGALPC---------------------------HQKNYTIAMRE-QNSVSNEGTQEILIA 397
           NGALPC                            Q  Y  A  E Q    N+    I  A
Sbjct: 374 NGALPCKLLLIKVNPDQFVTGERRTPEQRQAEREQAAYDQAPAEPQERQYNKNGNPIKPA 433

Query: 398 PD--------------FANRLKKNFNKIGKWAKREGLDCFRLYDADLPEYNVAIDVYQDH 443
           P               FANRL+KN   +GKWAKREG+DC+R+YDAD+PEY++AID+Y D 
Sbjct: 434 PAPVVEQARLSEGGQMFANRLQKNLKLLGKWAKREGVDCYRVYDADMPEYSMAIDLYHDW 493

Query: 444 LMIQEYAAPKDIPEEKAKRRLTDIIRAAIQVLDVDANNVVLKVRERQKGTSQYEKLGQQA 503
           + +QEYAAPK I  EKA  R+ D + A  Q L++D + VV+K RERQ GT QYE+   Q 
Sbjct: 494 VHVQEYAAPKSIDPEKASARMFDALAAIPQALNIDKSRVVVKRRERQSGTKQYERQSAQG 553

Query: 504 QTMQITEYGVKLIVNLYDYLDTGLFLDHKITRRRLGQMAQGKDFLNLFAYTGSATVHAAC 563
           +  +++E GVKL+VNL DYLDTGLFLDH+  R R+ + A GK FLNL+ YT +A+VHAA 
Sbjct: 554 KFTEVSEGGVKLLVNLTDYLDTGLFLDHRPMRLRIQKEAAGKRFLNLYCYTATASVHAAK 613

Query: 564 GGAKSTTTVDMSKTYLEWAKENMQLNGQVGRQHQYVQADCLQWLANAQSQYDLIFIDPPT 623
           GGA+STT+VD+SKTYL+WA+ N  LNG    +++  Q D + WL  ++ ++DLIFIDPPT
Sbjct: 614 GGARSTTSVDLSKTYLDWARRNFSLNG-FSDKNRLEQGDVMAWLETSRDEFDLIFIDPPT 672

Query: 624 FSNSKRMEQTFDVQRDHVTLMTNLKRLLRPEGTIVFSNNKRHFKMDMEALHALGLNAQNI 683
           FSNSKRME  FDVQRDHV L+      L P G + FSNN R F ++        +  + I
Sbjct: 673 FSNSKRMEGIFDVQRDHVQLLDLAMARLAPGGVLYFSNNFRKFALEDNLSERYAV--EEI 730

Query: 684 SHQTLPLDFERNKQIHNCWLIT 705
           S +T+  DF RN +IH  W IT
Sbjct: 731 SDKTIDPDFARNAKIHRAWKIT 752