Pairwise Alignments

Query, 708 a.a., ribosomal RNA large subunit methyltransferase K/L from Vibrio cholerae E7946 ATCC 55056

Subject, 708 a.a., bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL from Dickeya dianthicola ME23

 Score =  812 bits (2097), Expect = 0.0
 Identities = 400/707 (56%), Positives = 514/707 (72%), Gaps = 5/707 (0%)

Query: 1   MNQYLAVTSNGLENLLVEELTQLGINDAKPVQAGVKFKATNEQIYRCCLWSRLASRFVRI 60
           MN   A T+ GLE LL  EL  LG      VQ GV F+  +  +Y+  +WSRLASR +  
Sbjct: 1   MNSLFASTARGLEELLKSELEALGAQQCTVVQGGVHFQGEDRLLYQSLMWSRLASRILLP 60

Query: 61  VAEFKCQNDLDLYLSTTSVNWVNYFHSSKKLVVDFNGTNREIRNSQYGAMKVKDAIVDCF 120
           + EFK  +DLDLYL   +V+W   F  +    V F GTN EIRNSQYGA+KVKDAIVD F
Sbjct: 61  LNEFKVYSDLDLYLGVQAVDWSAVFSVNHTFAVHFTGTNDEIRNSQYGALKVKDAIVDSF 120

Query: 121 TKKNLPRPSISKDLADLHIHVRLHKENALLGIDMVGSGLHARGYRTEAGKAPLRETLAAA 180
           ++K   RP +++   D+ I+V L +E A + +D+ G  LH RGYR  AG+APL+E+LAAA
Sbjct: 121 SRKTGQRPDVARQQPDIRINVFLQREKASVALDLSGESLHLRGYRDMAGQAPLKESLAAA 180

Query: 181 IILRSGWDASKPLLDPMCGSGTLLIEAAMMAANIAPGLQRKKWGFEALEDFEPELWASVK 240
           I+LRSGW+   P++DPMCGSGTLLIEAAMMAA+ APGL R+ WGF A +  +P LW SV 
Sbjct: 181 IVLRSGWEVGTPMVDPMCGSGTLLIEAAMMAADRAPGLHRQHWGFLAWQKHDPTLWKSVI 240

Query: 241 SEASVQGKRGVKKVETHFYGVDNDNRVLQTAKDNARRAGVEELISFTLGDAAKVKRP-EN 299
           +EA  + + G++   + F+G D D R+++ A  NARRAGV  LI F   DA ++K P   
Sbjct: 241 TEAQERAQAGLQATPSRFFGSDVDRRMVEIASSNARRAGVSSLIRFEATDATQLKNPLPQ 300

Query: 300 FAEGIVICNPPYGERLGTHPGLIALYTAFGAQLKAEFGGCHASIFSSSDELLSCLRMRAD 359
              G VI NPPYGERL + P LIAL+   G ++K+EFGG   S+FS+S ELLSCL++RAD
Sbjct: 301 GPTGTVISNPPYGERLESEPALIALHNLLGRKMKSEFGGWKLSLFSASPELLSCLQLRAD 360

Query: 360 KQFKLNNGALPCHQKNYTIAMREQNSVSNEGTQEILIAPDFANRLKKNFNKIGKWAKREG 419
           +QFK  NG L C QKNY +A +E  + +   T     A DFANRL+KN  K+ KWA ++G
Sbjct: 361 RQFKAKNGPLECVQKNYQLAEKEDGAENAAAT----FAEDFANRLRKNLRKLEKWAAQQG 416

Query: 420 LDCFRLYDADLPEYNVAIDVYQDHLMIQEYAAPKDIPEEKAKRRLTDIIRAAIQVLDVDA 479
           ++C+RLYDADLPEYNVA+D Y + ++IQEYA PK I  +KA++RL D+I A + VL + A
Sbjct: 417 IECYRLYDADLPEYNVAVDRYGERVVIQEYAPPKSIDAQKARQRLFDVINATLSVLALPA 476

Query: 480 NNVVLKVRERQKGTSQYEKLGQQAQTMQITEYGVKLIVNLYDYLDTGLFLDHKITRRRLG 539
           +++VLK RERQKG SQYEKLG++ + +Q++E+  KL VNL DYLDTGLFLDH+I RR LG
Sbjct: 477 SHLVLKTRERQKGNSQYEKLGEKGEFLQVSEFNAKLWVNLTDYLDTGLFLDHRIARRMLG 536

Query: 540 QMAQGKDFLNLFAYTGSATVHAACGGAKSTTTVDMSKTYLEWAKENMQLNGQVGRQHQYV 599
           +M+ GKDFLNLFAYT SA+VHA  GGA+STTTVDMS+TYLEWA++N++LNG  GRQH+ +
Sbjct: 537 EMSNGKDFLNLFAYTASASVHAGLGGARSTTTVDMSRTYLEWAEKNLRLNGLTGRQHRLI 596

Query: 600 QADCLQWLANAQSQYDLIFIDPPTFSNSKRMEQTFDVQRDHVTLMTNLKRLLRPEGTIVF 659
            ADCL W+   + Q+DLIFIDPPTFSNSKRM+++FDVQRDH+ LM  LKRLLRP GTI+F
Sbjct: 597 HADCLAWMRETREQFDLIFIDPPTFSNSKRMDESFDVQRDHLMLMAQLKRLLRPRGTILF 656

Query: 660 SNNKRHFKMDMEALHALGLNAQNISHQTLPLDFERNKQIHNCWLITH 706
           SNNKR F+MD+  L ALGL A+ I+ QTL  DF RN+QIHNCWL+ H
Sbjct: 657 SNNKRGFQMDLAGLAALGLEAKEITGQTLSQDFARNRQIHNCWLLKH 703