Pairwise Alignments

Query, 312 a.a., siroheme synthase from Vibrio cholerae E7946 ATCC 55056

Subject, 457 a.a., fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase from Escherichia coli BL21

 Score =  143 bits (361), Expect = 7e-39
 Identities = 88/266 (33%), Positives = 145/266 (54%), Gaps = 5/266 (1%)

Query: 1   MRYFPLFLDLTNKPVLVVGGGEVACRKIDALLRADAKVTVISPQVAPALQAWIEQGKCHW 60
           M + P+F  L ++  L+VGGG+VA RK   LL A A++TV +    P   AW + G    
Sbjct: 1   MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTL 60

Query: 61  IQHFYSSHWLDKRYVQVWATTDNPELNHQVYKDAKEQGILVNVVDDQPYCDFITPSMIER 120
           ++  +    LD  ++ + A TD+  LN +V + A+ + I  NVVD      FI PS+I+R
Sbjct: 61  VEGPFDESLLDTCWLAI-AATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDR 119

Query: 121 GRIQLAISSGGASPVLIRNIRETLEAVLAQNLALLADFGASKRNSIKDFLPSVDLRRQFW 180
             + +A+SSGG SPVL R +RE LE++L  +L  +A +    R  +K    ++  RR+FW
Sbjct: 120 SPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFW 179

Query: 181 ERFFAHPEVKNA---QDRESLERIYIHLLTQSTDKVSATTWIEFG-ADVELLSLKALRYM 236
           E+ F +  +  +    D++++      L+ +  D       +  G  D  LL+LK L+ +
Sbjct: 180 EKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQI 239

Query: 237 QQAELVLHTQDCPFVFVDLCRRDAQR 262
           QQA++V++ +      ++L RRDA R
Sbjct: 240 QQADVVVYDRLVSDDIMNLVRRDADR 265