Pairwise Alignments

Query, 1331 a.a., hybrid sensor histidine kinase/response regulator from Vibrio cholerae E7946 ATCC 55056

Subject, 918 a.a., hybrid sensory histidine kinase, in two-component regulatory system with UvrY (NCBI) from Escherichia coli BW25113

 Score =  341 bits (874), Expect = 2e-97
 Identities = 230/693 (33%), Positives = 359/693 (51%), Gaps = 26/693 (3%)

Query: 554  GVQREMLVYEASFSDRADKVNGIVGILLDMTERKEMED-ELRKAKEAADAMSQAKGDFLA 612
            G+    +   A   +    ++     L +  E+ E+++ EL  AK+ A   ++ K +FLA
Sbjct: 239  GINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLA 298

Query: 613  NMSHEIRTPMNAILGMAHLALNTPLDTTQRKYVTRINESAKNLLGIINDILDFSKMEAGK 672
            NMSHE+RTP+N ++G   L L T L  TQR ++  I  SA NLL IIND+LDFSK+EAGK
Sbjct: 299  NMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGK 358

Query: 673  LNVERIDFNLDDVLDNVTAVVSLKAQEKGIEFLMDIDPHIPLGLIGDPLRLGQVMVNLCG 732
            L +E I F L   LD V  +++  + +KG+E  ++I   +P  +IGDPLRL Q++ NL G
Sbjct: 359  LILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVG 418

Query: 733  NAVKFTSQGEIVLSARVSQLNEQQVTLRFAVKDTGIGIAQDKLDDLFDAFSQADNSITRQ 792
            NA+KFT  G I +      L+  +V +   ++DTGIGI +     LF AF QAD SI+R+
Sbjct: 419  NAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRR 478

Query: 793  YGGTGLGLSISKQLVELMGGQITVHSEEGKGSTFEFSVVCGLQDAKMRDISQPVHGLADK 852
            +GGTGLGL I+++LV  MGG I+ HS+  +GSTF F +   L    + +       LA K
Sbjct: 479  HGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIE-GPSTQCLAGK 537

Query: 853  RVLVVDDNDSARHILDSLLTAMRFNVVTVSNGFEALSEIQQKPFDMLFVDWNMPGMNGIE 912
            R+  V+ N +A      +L+     VV  S  F AL       +DM+ +   +       
Sbjct: 538  RLAYVEPNSAAAQCTLDILSETPLEVV-YSPTFSALPPAH---YDMMLLGIAVTFRE--P 591

Query: 913  LLTRVKTLGLRGHMKSFLVTAYGREINLDGENSKL--VDALIVKPVNPSNLLDAIVTSYG 970
            L  + + L     M  FL+ A      ++ E  K   + A ++KP+ P+ LL A+     
Sbjct: 592  LTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALT---- 647

Query: 971  IEHVRHKTNEAHHNSRPNFAGQSLLLVEDNEVNQEVALGLLQDTGLNVVVANHGQEALER 1030
             E   HK N     +  +    +++ V+DN  N ++   LL+D   +V + + G +A+ER
Sbjct: 648  -EFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVER 706

Query: 1031 LEHADFDLVLMDMQMPVMDGITATEHIRANPRWHSLPIVAMTANAMAIDIERCLQAGMND 1090
             +   FDL+LMD+QMP MDGI A E I   P     P++A+TA+AMA   E+ L AGM+D
Sbjct: 707  AKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSD 766

Query: 1091 HLSKPIEVDKFYQVLRHFLQVSDEQSFSSHSPNKPSASKPAMNALLDLPQLTGVDLEQAI 1150
            +L+KPIE ++ + +L  +   S   S             P +N ++  P  T +D + A+
Sbjct: 767  YLAKPIEEERLHNLLLRYKPGSGISS---------RVVTPEVNEIVVNPNAT-LDWQLAL 816

Query: 1151 FRIGGNQQRYFEILRHFIDSQVDELNSVTGLIEAQDWSSATRVAHTLKGSAANLGLEALA 1210
             +  G      ++L+  +D   +  N V   +  ++      + H L GS    G+  + 
Sbjct: 817  RQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMK 876

Query: 1211 QLAAEMEQSLEQQVLPSFELLQQAQSLLTQVDD 1243
             L   +EQ L        +L  +   LL ++D+
Sbjct: 877  NLCQLIEQQLRSGTKEE-DLEPELLELLDEMDN 908