Pairwise Alignments

Query, 505 a.a., fumarate hydratase from Vibrio cholerae E7946 ATCC 55056

Subject, 548 a.a., class I fumarate hydratase from Escherichia coli ECRC62

 Score =  194 bits (492), Expect = 9e-54
 Identities = 155/513 (30%), Positives = 237/513 (46%), Gaps = 42/513 (8%)

Query: 7   QDVISSVADALQYISY--YHPLDFVKALEKAYQREESQAAKDSIA---------QILINS 55
           Q+++    +AL  ++   +H   F+  L  A+Q++ +   +D  A         Q L NS
Sbjct: 37  QEILKVAPEALTLLARQAFHDASFM--LRPAHQQQVADILRDPEASENDKYVALQFLRNS 94

Query: 56  RMSAEGHRPICQDTGIVTCFVNIGMGVQWDSTDMTVQQMVDEGVRQAYTNPDNPLRASVL 115
            ++A+G  P CQDTG        G  V     D   +  +  GV   Y   +     +  
Sbjct: 95  DIAAKGVLPTCQDTGTAIIVGKKGQRVWTGGGD---EAALARGVYNTYIEDNLRYSQNAP 151

Query: 116 MDPAGKRINTKDNTPAVVHINMVPGDKVDIQIAAKGGGSENKTKM-----VMLNPSDDIA 170
           +D   K +NT  N PA + +  V GD+      AKGGGS NKT +      +L P   + 
Sbjct: 152 LDMY-KEVNTGTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGK-LK 209

Query: 171 EWVEKTVPLMGAGWCPPGMLGIGIGGT-AEKAAVLAKEALMEHIDI--HELIERGPQNAE 227
            ++ + +  +G   CPP  +   IGGT AE      K A  ++ D    E  E G    +
Sbjct: 210 NYLVEKMRTLGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRD 269

Query: 228 EELRLDIFNRVNKLGIGAQGLGGLTTVVDVKIKSAPTHAASKPVCMIPNCAATRHVHFTL 287
            EL  ++      LG+GAQ  GG     D+++   P H AS PV M  +C+A R++   +
Sbjct: 270 VELEKELLIEAQNLGLGAQ-FGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKI 328

Query: 288 DGSGPAQLTPPKLEDWP------QITWEAGANTRRVNLDNITRE---EIQTWKTGETVLL 338
           +  G   +   KLE  P      ++         RV+L+   +E   ++  +     + L
Sbjct: 329 NRQG---IWIEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSL 385

Query: 339 SGKILTGRDAAHKRIQTMLQKGEKLPDSVDLKDKFIYYVGPVDAVGDEVVGPAGPTTSTR 398
           +G I+ GRD AH +++  +  GE LP  +  KD  IYY GP         G  GPTT+ R
Sbjct: 386 NGTIIVGRDIAHAKLKERMDNGEGLPQYI--KDHPIYYAGPAKTPEGYASGSLGPTTAGR 443

Query: 399 MDKFTDMMLEEVGVMGMIGKAERGPATVESIKKHKAVYLMAVGG-AAYLVAKAIKKARVV 457
           MD + D +  + G M M+ K  R     ++ KKH   YL ++GG AA L   +IK    V
Sbjct: 444 MDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECV 503

Query: 458 AFEDLGMEAIYEFEVEDMPVTVAVDSTGANAHQ 490
            + +LGMEAI++ EVED P  + VD  G +  Q
Sbjct: 504 EYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536