Pairwise Alignments

Query, 894 a.a., DNA topoisomerase (ATP-hydrolyzing) subunit A from Vibrio cholerae E7946 ATCC 55056

Subject, 906 a.a., DNA gyrase subunit A from Agrobacterium fabrum C58

 Score =  799 bits (2063), Expect = 0.0
 Identities = 439/934 (47%), Positives = 598/934 (64%), Gaps = 96/934 (10%)

Query: 17  LRSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMNVLGNDWNKAYKKSARVVGDVIGK 76
           ++ SYLDYAMSVIV RALPDVRDGLKPVHRR+L+ M+ LG DWNK Y K ARV GDV+GK
Sbjct: 1   MQRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYGMSELGIDWNKKYVKCARVTGDVMGK 60

Query: 77  YHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEVRMSKIAHELLA 136
           +HPHG+SA+YD + RMAQ +SLR  L+DGQGNFGSIDGD  AA RYTE R+ K AH LL 
Sbjct: 61  FHPHGNSAIYDALARMAQDWSLRLPLIDGQGNFGSIDGDPPAAERYTECRLEKAAHSLLD 120

Query: 137 DLDKETVDYVPNYDGTEQIPAVLPTKIPNLLINGASGIAVGMATNIPPHNLGEVIDGCLA 196
           DLDKETVD+  NYDGT Q P V+P K PNLL+NGA GIAVGMATNIPPHNL EVIDGC+A
Sbjct: 121 DLDKETVDFRDNYDGTLQEPVVVPAKFPNLLVNGAGGIAVGMATNIPPHNLSEVIDGCVA 180

Query: 197 YIDNEAITIDELMDYIPGPDFPTAALISGRKGIIDAYKTGRGKVYMRSKAEIETDKNGKE 256
            I+N AI + E+M  IPGPDFPT ALI GR GI  AY+TGRG V MR  A IE  +  +E
Sbjct: 181 LIENPAIELPEMMQIIPGPDFPTGALIMGRSGIRSAYETGRGSVIMRGVATIEPMRGDRE 240

Query: 257 TIIVSEIPYQVNKARLIEKIAELVKEKKVEGISALRDESDKDGMRIVIECKRDAVGEVVL 316
            II++E+PYQVNKA +IEK+AELVKEK++EGIS LRDESD+ G R+VIE KRDA  EV+L
Sbjct: 241 QIIITEVPYQVNKASMIEKMAELVKEKRIEGISDLRDESDRQGYRVVIELKRDANAEVIL 300

Query: 317 NNLYANTQLQTTFGINMVALDNGQPKLFNLKEMLKCFVDHRREVVTRRTIFELRKARERA 376
           N LY  T LQT+FG NMVAL+ G+P+   L +ML+ FV  R +VV+RRT + LRKAR+RA
Sbjct: 301 NQLYRYTPLQTSFGCNMVALNGGKPEQMTLLDMLRAFVSFREDVVSRRTKYLLRKARDRA 360

Query: 377 HILEGLALALANIDEIIELIRRAATPAEAKEGLIARGWDLGNVAAMLERAGTDAARPEWL 436
           H+L GLA+++ANIDE+I +IR A  PA A+E L+ R W   +V +++             
Sbjct: 361 HVLVGLAISVANIDEVIRVIRHAPDPASAREQLMTRRWPAQDVESLIRLID--------- 411

Query: 437 EPQYGI-RDGKYFLTEQQAQAILDLRLHKLTGLEHEKILDEYKQLLEEIAALMHILASTE 495
           +P++ I  DG Y L+E+QA+AIL+LRL +LT L  ++I DE  ++  EI+  + IL+S  
Sbjct: 412 DPRHRINEDGTYNLSEEQARAILELRLARLTALGRDEIGDELNKIGAEISEYLDILSSRV 471

Query: 496 RLMEVIREELEAIRAGFSDARRTEITAATHDIDMEELIAREDVVVTLSHEGYVKYQLLSD 555
           R+ +++++EL +IR  F   RR++I     D+D E+LIARED+VVT+SH GY+K   L+ 
Sbjct: 472 RIQQIVKDELVSIRDEFGTPRRSQIVEGGPDMDDEDLIAREDMVVTVSHLGYIKRVPLTT 531

Query: 556 YEAQRRGGKGKSATKMKEEDYIERLLVANTHDNILLFSTRGKTYRMKVYQLPLASRTARG 615
           Y AQRRGGKG+S    ++ED++ RL VANTH  +L FS+RG  Y+ KV++LP+ +  ++G
Sbjct: 532 YRAQRRGGKGRSGMATRDEDFVNRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSKG 591

Query: 616 KPIVNLLPLEENERITAILPVTEFS---EDKFIFMATGDGTVKKTSLDQFANVRANGLIA 672
           K ++N+LPLE  ERIT I+P+ E     E   +  +T  GTV++  L  F  V  NG IA
Sbjct: 592 KALINMLPLEPGERITTIMPLPEDETAWETLDVMFSTTRGTVRRNKLGDFVQVNRNGKIA 651

Query: 673 LNLRDE-DSLIGVDITDGESEIMLFSKFGKVVRFKESEETAVVDENGQPVLDENGQPEIK 731
           + L +E D ++ V+      +++L +  G+ +RF              PV D        
Sbjct: 652 MKLDEEGDEILSVETCTDRDDVLLTTALGQCIRF--------------PVDD-------- 689

Query: 732 FKGVRPM-GRTAAGVRGMKLADGDQVVSLIV-------------------------PKTE 765
              VR   GR + GVRG+ +A+GD+++S+ +                            E
Sbjct: 690 ---VRVFAGRNSVGVRGINMAEGDRIISMTIVGHVEAEPWERAAYLKRSATERRAAGVDE 746

Query: 766 GDVLTVTE----------------------------NGYGKRTSLSEYPTKGRGTQGVVS 797
            D+  V E                             G+GKR+S  ++ T GRG +G+ +
Sbjct: 747 EDIALVGEEVTEEGELSEERYQELKAREEFVLTVSVKGFGKRSSSYDFRTSGRGGKGIRA 806

Query: 798 IKVSERN--GSVVGAVQVAEGDEFMMITNAGTLVRTRVAEVSQVGRNTQGVTLIRTSEGE 855
              ++ N  G +V A  V EGD+ M++++ G L+R  V  +    R T+GVT+  T++ E
Sbjct: 807 TDTAKTNEIGELVAAFPVEEGDQIMLVSDGGQLIRVPVNGIRIASRATKGVTIFSTAKDE 866

Query: 856 SVVGLQRIDEIE-ESELPEGEEALVENDAPVAQD 888
            VV ++RI+E E + E   G +   +++ P A +
Sbjct: 867 KVVSVERINEPEGDDEAENGNDDEADDNLPDAPE 900