Pairwise Alignments

Query, 761 a.a., ribonucleoside-diphosphate reductase subunit alpha from Vibrio cholerae E7946 ATCC 55056

Subject, 714 a.a., ribonucleotide-diphosphate reductase alpha subunit (NCBI) from Escherichia coli BW25113

 Score =  162 bits (411), Expect = 4e-44
 Identities = 169/719 (23%), Positives = 292/719 (40%), Gaps = 67/719 (9%)

Query: 65  SAADLISEETPDYQYLAARLAVFHLRKKAYGQYEPPTLLAHVTK---------------- 108
           + A+ +++ET DY  L A L ++    +     +   + A +                  
Sbjct: 4   TTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQQRL 63

Query: 109 --MVEKGKYDKHLLEDYTREELELMDQFIDHRRDLDFSYAAVKQLEGKYFVQNRVTGQIY 166
             +V +G YD+ +L  Y+R+    +     H     F +   +   G +      T + +
Sbjct: 64  NWLVNEGYYDESVLNRYSRD---FVITLFTHAHTSGFRF---QTFLGAWKFYTSYTLKTF 117

Query: 167 ESAQFLY-----ILVAACLFAKYPKETRLDYIKRFYDATSTFKISLPTPIMSGVRTPTRQ 221
           +  ++L      + + A   A+  +   L         +  F+ + PT +  G +    +
Sbjct: 118 DGKRYLEDFADRVTMVALTLAQGDETLALQLTDEML--SGRFQPATPTFLNCG-KQQRGE 174

Query: 222 FSSCVLIECGDSLDSINATASSIVRYVSQRAGIGINAGRIRALGSEIRGGEAFHTGCIPF 281
             SC L+   D+++SI    +S ++   +  G+      +R  G+ I+  E   +G IP 
Sbjct: 175 LVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPV 234

Query: 282 YKYFQTAVKCCSQGGVRGGAATVFYPLWHGEAESLLVLKNNRGVEENRVRHMDYGVQLNK 341
            K  + A    +Q G R GA  V+    H +    L  K     E+ R++ +  GV +  
Sbjct: 235 MKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPD 294

Query: 342 LMYKRLVEGGNITLFSPSDVPGLYDAFFQDQDEFERLYVKYENDPSIKKKTVKALEIFTL 401
           + +    E   + LFSP DV  +Y   F D     + Y +   D  I+KK + A + F  
Sbjct: 295 ITFHLAKENAQMALFSPYDVERVYGKPFADV-AISQHYDELVADERIRKKYLNARDFFQR 353

Query: 402 LMQERASTGRIYIQNVDHCNTHSPFDAAVAPVRQSNLCLEIALPTSPLANVED----ESG 457
           L + +  +G  YI   D  N  +P       +  SNLC EI    S     E+     +G
Sbjct: 354 LAEIQFESGYPYIMYEDTVNRANPI---AGRINMSNLCSEILQVNSASEYDENLDYTRTG 410

Query: 458 EIALCTLSAFNLGAIESLDDFEELSDLVVRALDALLDYQDY-PLPAARRSSMNRRTLGVG 516
               C L + N+       DF    +  VR L A+ D      +P+    +     +G+G
Sbjct: 411 HDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLG 470

Query: 517 VINYAYYLAKNGVKYSDGSANGLTHRTFEAMQYHLLRASMKLAKEQGRC-PLFHETNYAK 575
            +N   YLA+ G+ Y    A   T+  F A+ +H LR SM LA+E+G     F ++ YA 
Sbjct: 471 QMNLHGYLAREGIAYGSPEALDFTNLYFYAITWHALRTSMLLARERGETFAGFKQSRYAS 530

Query: 576 GLMPIDTYKKDIDLVCAE------------PLHYDWDKLRHEIMEHGLRNSTLTALMPSE 623
           G       + +     A+            P    W +LR ++M +G+ N  L A+ P+ 
Sbjct: 531 GEYFSQYLQGNWQPKTAKVGELFTRSGITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTG 590

Query: 624 TSSQISNATNGIEPPRGYVSV-KASKDGILKQVVPEFTRLKEN---YELLWNIGSNDGYL 679
           + S I++AT+ I P    V + K  K G +    P  T   EN   Y+  + IG+ +  +
Sbjct: 591 SISYINHATSSIHPIVAKVEIRKEGKTGRVYYPAPFMT--NENLALYQDAYEIGA-EKII 647

Query: 680 HLVGIMQKFVDQAISANTNYDPSNFDSGKVPMKKLLQDLLTAYKFGVKTLYYHNTRDGA 738
                  + VDQ +S         F       + + +  + A++ G+KTLYY   R  A
Sbjct: 648 DTYAEATRHVDQGLSLTL------FFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMA 700