Pairwise Alignments

Query, 562 a.a., NAD-dependent malic enzyme from Vibrio cholerae E7946 ATCC 55056

Subject, 775 a.a., NADP-dependent malic enzyme (EC 1.1.1.40) from Hydrogenophaga sp. GW460-11-11-14-LB1

 Score = 87.4 bits (215), Expect = 2e-21
 Identities = 116/457 (25%), Positives = 187/457 (40%), Gaps = 106/457 (23%)

Query: 97  MPIIYTPTVGAACENFS----NIYRRGRGLFISYANRDRIDDLLNNAANHNVKVIVVTDG 152
           + + Y+P V A CE       N Y+        Y +R  +             V V+T+G
Sbjct: 44  LALAYSPGVAAPCEEIVADPVNAYK--------YTSRGNL-------------VAVITNG 82

Query: 153 ERILGLGDQG-IGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTN--NPQRLADPMYMG 209
             +LGLGD G +    +  GK  L+    G+        V D+  N  +P +L + +   
Sbjct: 83  TAVLGLGDIGPLAAKPVMEGKGVLFKKFAGVD-------VFDIEINEKDPAKLVEVI--- 132

Query: 210 WRHPRITGPDYDNFVEEFMQAVQRRWPDALIQFEDFAQKNAMPLLERYKNRVCCFNDDIQ 269
                   P +     E ++A     PD      +  ++  +P+          F+DD  
Sbjct: 133 ----AALEPTFGAINLEDIKA-----PDCFYVERELRKRLKIPV----------FHDDQH 173

Query: 270 GTAAVTVGSLLAACKAAGSQLSQQRITFLGAGSAGCGIAEAIIAQMVSEGISDEQARSQV 329
           GTA     ++L   K AG  + Q ++   GAG+A    A A +  ++  G+     R  V
Sbjct: 174 GTAITVAAAMLNGLKVAGKDIGQVKLVTSGAGAA----ALACLNLLLKVGLK----RENV 225

Query: 330 YMVDRWGLLEEGMPNLLDFQQRLVQKKANTQHWTTENNGYSLHDVIRNAKPTVLVGVSGA 389
           ++ D  G++ EG   L+D  +R   +K + +          L +VI  A   V +G+S A
Sbjct: 226 FVTDLAGVVYEGREELMDDDKRQYMQKTDKR---------KLAEVIVGA--DVFLGLS-A 273

Query: 390 PGLFSEEIIKEMHQHCPRPIVFPLSNPTSRVEALPSDIIRWTNGEALVATGSPFDPVLHE 449
            G+   E++  M     RP++F L+NP   +    +  +R    + ++ATG         
Sbjct: 274 GGVLKPEMVASM---AARPVIFALANPNPEIAPEDAHAVR---NDIIMATGR-------- 319

Query: 450 GKTYPIVQCNNSYIFPGIGLGVLAANARRVTDEMLMESSRALASCSPLAIN--------- 500
              YP  Q NN   FP I  G L A A  +TDEM + +  A+A  +    +         
Sbjct: 320 -TDYP-NQVNNVLCFPYIFRGALDAGASTITDEMEIAAVHAIAELAQAEQSEVVAAAYAG 377

Query: 501 ---GHGP-LLPPLESIHSVSKKIAFAVAKKAIEQGVA 533
                GP  L P      +  KIA AVA+ A++ GVA
Sbjct: 378 EKLAFGPEYLIPKPFDPRLMMKIAPAVAQAAVDSGVA 414