Pairwise Alignments

Query, 562 a.a., NAD-dependent malic enzyme from Vibrio cholerae E7946 ATCC 55056

Subject, 565 a.a., NAD-linked malate dehydrogenase (malic enzyme) (VIMSS) from Escherichia coli BW25113

 Score =  807 bits (2085), Expect = 0.0
 Identities = 390/557 (70%), Positives = 461/557 (82%)

Query: 5   KRPLYISYAGPALLSTPLLNKGSAFSAEERASFNLEGLLPEATETIQEQVVRAYQQYRGF 64
           +R LYI YAGP LL  PLLNKGSAFS EER +FNL GLLPE  ETI+EQ  RA+ QY+GF
Sbjct: 8   QRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGF 67

Query: 65  ESDMDKHIYLRNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFI 124
           ++++DKHIYLRNIQDTNETLFYRLV NH+ EMMP+IYTPTVGAACE FS IYRR RG+FI
Sbjct: 68  KTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFI 127

Query: 125 SYANRDRIDDLLNNAANHNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISP 184
           SY NR  +DD+L N  NHN+KVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISP
Sbjct: 128 SYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISP 187

Query: 185 AYTLPVVLDVGTNNPQRLADPMYMGWRHPRITGPDYDNFVEEFMQAVQRRWPDALIQFED 244
           AYTLPVVLDVGTNN Q L DP+YMGWR+PRIT  +Y  FV+EF+QAV++RWPD L+QFED
Sbjct: 188 AYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFED 247

Query: 245 FAQKNAMPLLERYKNRVCCFNDDIQGTAAVTVGSLLAACKAAGSQLSQQRITFLGAGSAG 304
           FAQKNAMPLL RY+N +C FNDDIQGTAAVTVG+L+AA +AAG QLS+++I FLGAGSAG
Sbjct: 248 FAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAG 307

Query: 305 CGIAEAIIAQMVSEGISDEQARSQVYMVDRWGLLEEGMPNLLDFQQRLVQKKANTQHWTT 364
           CGIAE II+Q   EG+S+E AR +V+MVDR+GLL + MPNLL FQ +LVQK+ N   W T
Sbjct: 308 CGIAEMIISQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDT 367

Query: 365 ENNGYSLHDVIRNAKPTVLVGVSGAPGLFSEEIIKEMHQHCPRPIVFPLSNPTSRVEALP 424
           +++  SL DV+RN KP +L+GVSG  GLF+EEII+EMH+HCPRPIV PLSNPTSRVEA P
Sbjct: 368 DSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATP 427

Query: 425 SDIIRWTNGEALVATGSPFDPVLHEGKTYPIVQCNNSYIFPGIGLGVLAANARRVTDEML 484
            DII WT G ALVATGSPF+PV+ + K YPI QCNN++IFPGIGLGV+A+ A R+TDEML
Sbjct: 428 QDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEML 487

Query: 485 MESSRALASCSPLAINGHGPLLPPLESIHSVSKKIAFAVAKKAIEQGVAPEVTDEALEAS 544
           M +S  LA  SPL +NG G +LP L+ I  VS+ IAFAV K A +QGVA + + EAL+ +
Sbjct: 488 MSASETLAQYSPLVLNGEGMVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQA 547

Query: 545 IEQHFWQPVYRRYKRTA 561
           I+ +FWQ  YR Y+RT+
Sbjct: 548 IDDNFWQAEYRDYRRTS 564