Pairwise Alignments

Query, 469 a.a., bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase from Vibrio cholerae E7946 ATCC 55056

Subject, 452 a.a., N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) from Escherichia coli BW25113

 Score =  534 bits (1376), Expect = e-156
 Identities = 278/456 (60%), Positives = 336/456 (73%), Gaps = 6/456 (1%)

Query: 16  MAQVLVKIVNDKYQWIEERKAKQPLASFHPLLTRSERDFYQALSGDNTVFILECKKASPS 75
           M  VL KIV DK  W+E RK +QPLASF   +  S R FY AL G  T FILECKKASPS
Sbjct: 1   MQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPS 60

Query: 76  KGLIREEFDLDYIASVYGEYASAISVLTDEKYFQGRFEFLPQVRAQVAQPVLCKDFMVDP 135
           KG+IR++FD   IA++Y  YASAISVLTDEKYFQG F FLP V     QP+LCKDF++DP
Sbjct: 61  KGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPIVSQIAPQPILCKDFIIDP 120

Query: 136 YQVYLARHYQADAILLMLSVLNDDQYRELAAVAHDLGMGVLTEVSNEQELKRAVDLQAKV 195
           YQ+YLAR+YQADA LLMLSVL+DDQYR+LAAVAH L MGVLTEVSNE+E +RA+ L AKV
Sbjct: 121 YQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGVLTEVSNEEEQERAIALGAKV 180

Query: 196 IGINNRNLRDLTTDLNRTKQLAPLIPQGTIIISESGIYTHQQVRDLAEFANGFLIGSSLM 255
           +GINNR+LRDL+ DLNRT++LAP +     +ISESGI T+ QVR+L+ FANGFLIGS+LM
Sbjct: 181 VGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFANGFLIGSALM 240

Query: 256 AQSNLELAVRKIVLGEHKVCGLTHPDDAVKAYQAGSVFGGLIFVEKSKRFVDVEQARLTM 315
           A  +L  AVR+++LGE+KVCGLT   DA  AY AG+++GGLIFV  S R V+VEQA+  M
Sbjct: 241 AHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVM 300

Query: 316 SGAPLQYVGVFQNHPAAQVADIATKLGLFAVQLHGEEDSAYVSELRASLPESIEIWKAYG 375
           + APLQYVGVF+NH  A V D A  L L AVQLHG E+  Y+  LR +LP  + IWKA  
Sbjct: 301 AAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLHGNEEQLYIDTLREALPAHVAIWKALS 360

Query: 376 VSDALPELLPEHIDRHLLDAKVGEQSGGTGRSFDWRLLPKHS--DLMLAGGLSAENVAQA 433
           V + LP    +H+D+++LD       GG+G+ FDW LL   S  +++LAGGL A+N  +A
Sbjct: 361 VGETLPAREFQHVDKYVLD----NGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEA 416

Query: 434 AQLGCRGLDFNSGVESAPGKKDANQLQQVFQQLRNY 469
           AQ GC GLDFNS VES PG KDA  L  VFQ LR Y
Sbjct: 417 AQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY 452