Pairwise Alignments

Query, 422 a.a., alcohol dehydrogenase from Vibrio cholerae E7946 ATCC 55056

Subject, 891 a.a., fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) from Escherichia coli BW25113

 Score =  112 bits (279), Expect = 6e-29
 Identities = 105/399 (26%), Positives = 172/399 (43%), Gaps = 31/399 (7%)

Query: 17  IIFGEGSLESSLSIISQYGYS-VLLVSGK---NAERYAPLTAYLQQQNMRYQ-HVVVSGE 71
           I F  GSL  +L  +   G+   L+V+ +   N      +T+ L+   +  +    V  +
Sbjct: 460 IYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEAD 519

Query: 72  PNITMVEEAAMLGRRFKPDMVIAIGGGSVLDMGKAVAAIIPNQGNVYDYVEVVGRSVPLK 131
           P +++V + A L   FKPD++IA+GGGS +D  K +  +  +    ++ + +    +  +
Sbjct: 520 PTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHFEELALRFMDIRKR 579

Query: 132 AKPLP-------FIAIPTTASSGSEVTRNAVLKSAQDRVKISLRSPEMLADVAIIDPTLT 184
               P        IA+ TT+ +GSEVT  AV+       K  L    +  D+AI+D  L 
Sbjct: 580 IYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLV 639

Query: 185 YGTDPVTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSRAMIAGCLRDDKK--A 242
                     G +DA TH MEAYV    +  +D    + L+ L   + A      K   A
Sbjct: 640 MDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVA 699

Query: 243 RSDLSFAAMLGGMATTNAKLGAAHGLASALGGKLDAPHSVITARLAPIVMRENID----- 297
           R  +  AA + G+A  NA LG  H +A  LG +   PH +  A L   V+R N +     
Sbjct: 700 RERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTK 759

Query: 298 --VAKEAGRSDILQRYKIVSRIL-----TGRKNAGVEDGILWVNMMLEKLSIP-NLTDFG 349
                +  R    +RY  ++  L       R  A +E  + W+  +  +L IP ++ + G
Sbjct: 760 QTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLAWLETLKAELGIPKSIREAG 819

Query: 350 VCATSF----ERVAADALKSTAIKGNPIPLTMERLTHIL 384
           V    F    ++++ DA        NP    +  L  IL
Sbjct: 820 VQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQIL 858